Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Pierre Tufféry"'
Autor:
Pierre Tufféry, Philippe Derreumaux
Publikováno v:
Frontiers in Bioinformatics, Vol 3 (2023)
Introduction: Peptides carry out diverse biological functions and the knowledge of the conformational ensemble of polypeptides in various experimental conditions is important for biological applications. All fast dedicated softwares perform well in a
Externí odkaz:
https://doaj.org/article/353a32142a63445780e3d3ffdd7a9b38
Autor:
Pierre Tufféry, Sjoerd de Vries
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 1790-1799 (2020)
Protein engineering or candidate therapeutic peptide optimization are processes in which the identification of relevant sequence variants is critical. Starting from one amino-acid sequence, the choice of the substitutions must meet the objective of n
Externí odkaz:
https://doaj.org/article/408ec15d068849518462e3ca9fd34710
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 2228-2236 (2020)
For three decades now, knowledge-based scoring functions that operate through the “potential of mean force” (PMF) approach have continuously proven useful for studying protein structures. Although these statistical potentials are not to be confus
Externí odkaz:
https://doaj.org/article/9716b687bc5c4a338707338c97df862c
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
In silico assessment of protein receptor interactions with small ligands is now part of the standard pipeline for drug discovery, and numerous tools and protocols have been developed for this purpose. With the SeamDock web server, we propose a new ap
Externí odkaz:
https://doaj.org/article/bf858e73b1054d9ab563ac6c421e9f4b
Autor:
Pierre Tufféry, Philippe Derreumaux
Introduction: Peptides carry out diverse biological functions and the knowledge of the conformational ensemble of polypeptides in various experimental conditions is important for biological applications. All fast dedicated softwares perform well in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5668d4953556751fb1caa898d60ebe5c
https://doi.org/10.1101/2022.12.20.521219
https://doi.org/10.1101/2022.12.20.521219
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2405
Amyloid fibril formation is an intrinsic property of short peptides, non-disease proteins, and proteins associated with neurodegenerative diseases. Aggregates of the Aβ and tau proteins, the α-synuclein protein, and the prion protein are observed i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7a525b18db758c1c80a88af5cf4bdc62
https://pubmed.ncbi.nlm.nih.gov/35298810
https://pubmed.ncbi.nlm.nih.gov/35298810
Autor:
Yasaman Karami, Samuel Murail, Julien Giribaldi, Benjamin Lefranc, Florian Defontaine, Olivier Lesouhaitier, Jérôme Leprince, Sjoerd J. de Vries, Pierre Tufféry
Backbone head-to-tail cyclization is one effective strategy to stabilize the conformation of bioactive peptides, preventing enzymatic degradation and improving their bioavailibility. However, very little is known about the requirements to rationally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72014cd095919246d45cad2f8e0d4aec
https://doi.org/10.1101/2022.01.05.475045
https://doi.org/10.1101/2022.01.05.475045
Publikováno v:
Methods in Molecular Biology ISBN: 9781071618547
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2547c4d673d8af20645d6dbd17b88c7e
https://doi.org/10.1007/978-1-0716-1855-4_5
https://doi.org/10.1007/978-1-0716-1855-4_5
Publikováno v:
Methods in Molecular Biology ISBN: 9781071617519
Methods for isolation of human primary cells is an important tool to be able to test the effect of several drugs for the treatment of diseases. Protocols have been described for the isolation of healthy and tumoral hepatocytes; however, the quality a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62a4656db030e593370c85ce037960eb
https://doi.org/10.1007/978-1-0716-1752-6_26
https://doi.org/10.1007/978-1-0716-1752-6_26
Autor:
Lorena Simón-Gracia, Eric Savier, Olivier Scatton, Frédéric Charlotte, Tambet Teesalu, Angelita Rebollo, Pierre Tufféry
Publikováno v:
Pharmaceutics
Pharmaceutics, MDPI, 2021, 13 (10), pp.1631. ⟨10.3390/pharmaceutics13101631⟩
Volume 13
Issue 10
Pharmaceutics, 2021, 13 (10), pp.1631. ⟨10.3390/pharmaceutics13101631⟩
Pharmaceutics, Vol 13, Iss 1631, p 1631 (2021)
Pharmaceutics, MDPI, 2021, 13 (10), pp.1631. ⟨10.3390/pharmaceutics13101631⟩
Volume 13
Issue 10
Pharmaceutics, 2021, 13 (10), pp.1631. ⟨10.3390/pharmaceutics13101631⟩
Pharmaceutics, Vol 13, Iss 1631, p 1631 (2021)
International audience; Background: The interfering peptides that block protein–protein interactions have been receiving increasing attention as potential therapeutic tools. Methods: We measured the internalization and biological effect of four bi-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33874811fd73e30986d36f14fd640f46
https://hal.sorbonne-universite.fr/hal-03405487/file/pharmaceutics-13-01631-v2.pdf
https://hal.sorbonne-universite.fr/hal-03405487/file/pharmaceutics-13-01631-v2.pdf