Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Pierre Therizols"'
Autor:
Sarah Tessier, Omar Ferhi, Marie-Claude Geoffroy, Román González-Prieto, Antoine Canat, Samuel Quentin, Marika Pla, Michiko Niwa-Kawakita, Pierre Bercier, Domitille Rérolle, Pierre Therizols, Emmanuelle Fabre, Alfred C. O. Vertegaal, Hugues de Thé, Valérie Lallemand-Breitenbach
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Here the authors identify novel PML-partners and demonstrate that PML NBs control their sumoylation and that PML-controlled sumoylation of transcriptional regulators maintains the embryonic stem cell transcriptome and transposable element silencing.
Externí odkaz:
https://doaj.org/article/5fa232a562fb4fdfab6f62d5a90021c8
Autor:
Sarah Tessier, Omar Ferhi, Marie-Claude Geoffroy, Román González-Prieto, Antoine Canat, Samuel Quentin, Marika Pla, Michiko Niwa-Kawakita, Pierre Bercier, Domitille Rérolle, Marilyn Tirard, Pierre Therizols, Emmanuelle Fabre, Alfred C. O. Vertegaal, Hugues de Thé, Valérie Lallemand-Breitenbach
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/43bf9cc247ef4f48ab070961d4555b8d
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 6, p e1004987 (2016)
Characterizing the link between small-scale chromatin structure and large-scale chromosome folding during interphase is a prerequisite for understanding transcription. Yet, this link remains poorly investigated. Here, we introduce a simple biophysica
Externí odkaz:
https://doaj.org/article/17f4d515900c4af3b6a740c7aba4ff82
Autor:
Marie-Claude Geoffroy, Sarah Tessier, Domitille Rérolle, Alfred C.O. Vertegaal, Pierre Bercier, Marika Pla, Román González-Prieto, Omar Ferhi, Emmanuelle Fabre, Valérie Lallemand-Breitenbach, Antoine Canat, Samuel Quentin, Pierre Therizols, Michiko Niwa-Kawakita
SummaryMembrane-less organelles are condensates formed by phase separation whose functions often remain enigmatic. Upon oxidative stress, PML scaffolds Nuclear Bodies (NBs) to regulate senescence or metabolic adaptation, but their role in pluripotenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::613ff069cce079371be051846bcc34fe
https://doi.org/10.1101/2021.06.29.450368
https://doi.org/10.1101/2021.06.29.450368
Autor:
Antoine Canat, Adeline Veillet, Renaud Batrin, Clara Dubourg, Robert Illingworth, Emmanuelle Fabre, Pierre Therizols
Genomes comprise a large fraction of repetitive sequences folded into constitutive heterochromatin to protect genome integrity and cell identity.De novoformation of heterochromatin during preimplantation development is an essential step for preservin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::615d561a368c4b87a88f344c7b1e45fe
https://doi.org/10.1101/2021.04.28.441827
https://doi.org/10.1101/2021.04.28.441827
Autor:
Sarah, Tessier, Omar, Ferhi, Marie-Claude, Geoffroy, Román, González-Prieto, Antoine, Canat, Samuel, Quentin, Marika, Pla, Michiko, Niwa-Kawakita, Pierre, Bercier, Domitille, Rérolle, Pierre, Therizols, Emmanuelle, Fabre, Alfred C O, Vertegaal, Hugues, de Thé, Valérie, Lallemand-Breitenbach
Publikováno v:
Nature communications. 13(1)
Membrane-less organelles are condensates formed by phase separation whose functions often remain enigmatic. Upon oxidative stress, PML scaffolds Nuclear Bodies (NBs) to regulate senescence or metabolic adaptation. PML NBs recruit many partner protein
Publikováno v:
Briefings in functional genomics. 19(2)
The spatial organization of the genome contributes to essential functions such as transcription and chromosome integrity maintenance. The principles governing nuclear compartmentalization have been the focus of considerable research over the last dec
Autor:
Graeme R. Grimes, Nezha S. Benabdallah, Dipta Sengupta, Iain Williamson, Robert S. Illingworth, Pierre Therizols, Lauren Kane, Shelagh Boyle, Wendy A. Bickmore
Publikováno v:
Molecular Cell
Benabdallah, N S, Williamson, I, Illingworth, R S, Kane, L, Boyle, S, Sengupta, D, Grimes, G R, Therizols, P & Bickmore, W A 2019, ' Decreased enhancer-promoter proximity accompanying enhancer activation ', Molecular Cell, vol. 76, no. 3, pp. 473-484.e7 . https://doi.org/10.1016/j.molcel.2019.07.038
Benabdallah, N S, Williamson, I, Illingworth, R S, Kane, L, Boyle, S, Sengupta, D, Grimes, G R, Therizols, P & Bickmore, W A 2019, ' Decreased enhancer-promoter proximity accompanying enhancer activation ', Molecular Cell, vol. 76, no. 3, pp. 473-484.e7 . https://doi.org/10.1016/j.molcel.2019.07.038
Summary Enhancers can regulate the promoters of their target genes over very large genomic distances. It is widely assumed that mechanisms of enhancer action involve the reorganization of three-dimensional chromatin architecture, but this is poorly u
Autor:
Shelagh Boyle, Pierre Therizols, Robert S. Illingworth, Iain Williamson, Nezha S. Benabdallah, Wendy A. Bickmore, Graeme R. Grimes
Enhancers are critical regulators of gene expression and can be located far from their target gene. It is widely assumed that mechanisms of enhancer action involve reorganization of three-dimensional chromatin architecture, but this is poorly underst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbaff66e50b723bca4dbb732989fab93
https://doi.org/10.1101/155325
https://doi.org/10.1101/155325
Publikováno v:
Journal of Biological Chemistry. 282:7690-7699
Fnr is a regulator that controls the expression of a variety of genes in response to oxygen limitation in bacteria. To assess the role of Fnr in photosynthesis in Rubrivivax gelatinosus, a strain carrying a null mutation in fnrL was constructed. It w