Zobrazeno 1 - 2
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pro vyhledávání: '"Pierre Souillac"'
Publikováno v:
Journal of pharmaceutical sciences. 110(5)
Lipoprotein lipase (LPL) is an essential enzyme that hydrolyzes triglycerides in chylomicrons and very low-density lipoprotein into glycerol and fatty acids. One major hurdle in using LPL as a therapeutic has been its poor solubility/stability after
Autor:
Vladimir N, Uversky, Jie, Li, Pierre, Souillac, Ian S, Millett, Sebastian, Doniach, Ross, Jakes, Michel, Goedert, Anthony L, Fink
Publikováno v:
The Journal of biological chemistry. 277(14)
The pathological hallmark of Parkinson's disease is the presence of intracellular inclusions, Lewy bodies, and Lewy neurites, in the dopaminergic neurons of the substantia nigra and several other brain regions. Filamentous alpha-synuclein is the majo