Zobrazeno 1 - 10
of 272
pro vyhledávání: '"Pierre Soubeyran"'
Autor:
P. A. L. Seghers, Shabbir M. H. Alibhai, Nicolò Matteo Luca Battisti, Ravindran Kanesvaran, Martine Extermann, Anita O’Donovan, Sophie Pilleron, Anna Rachelle Mislang, Najia Musolino, Kwok-Leung Cheung, Anthony Staines, Charis Girvalaki, Pierre Soubeyran, Johanneke E. A. Portielje, Siri Rostoft, Marije E. Hamaker, Dominic Trépel, Shane O’Hanlon
Publikováno v:
Global Health Research and Policy, Vol 8, Iss 1, Pp 1-8 (2023)
Abstract Most cancers occur in older people and the burden in this age group is increasing. Over the past two decades the evidence on how best to treat this population has increased rapidly. However, implementation of new best practices has been slow
Externí odkaz:
https://doaj.org/article/c937b0a9ea1845edaec3eb6349dd25d1
Autor:
Mylène Annonay, MD, Lisa Gauquelin, MD, Romain Geiss, MD, Mony Ung, MD, Laurence Cristol-Dalstein, MD, Marie-Ange Mouret-Reynier, MD PHD, Anthony Goncalves, MD PHD, Sophie Abadie-Lacourtoisie, MD, Eric Francois, MD, Christophe Perrin, MD, Johan Le Fel, MD, Véronique Lorgis, MD, Véronique Servent, MD, Lionel Uwer, MD, Christelle Jouannaud, MD, Marianne Leheurteur, MD, Florence Joly, MD PHD, Loic Campion, MD, Coralie Courtinard, MPH, Olivier Villacroux, MD, Thierry Petit, MD PHD, Pierre Soubeyran, MD, Catherine Terret, MD, Carine Bellera, PHD, Etienne Brain, MD PHD, Suzette Delaloge, MD MPH
Publikováno v:
Breast, Vol 60, Iss , Pp 138-146 (2021)
Background: Treatment and outcomes of patients with HER2-positive (HER2+) metastatic breast cancer (MBC) have dramatically improved over the past 20 years. This work evaluated treatment patterns and outcomes according to age. Methods: Women who initi
Externí odkaz:
https://doaj.org/article/ade3e6c3b78e4adab88c10f438f12991
Autor:
Clément Bodineau, Mercedes Tomé, Sarah Courtois, Ana S. H. Costa, Marco Sciacovelli, Benoit Rousseau, Elodie Richard, Pierre Vacher, Carlos Parejo-Pérez, Emilie Bessede, Christine Varon, Pierre Soubeyran, Christian Frezza, Piedad del Socorro Murdoch, Victor H. Villar, Raúl V. Durán
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
The metabolism of amino acids and the cellular energy sensor AMPK are both connected to mTORC1, but the pathway details have not been well defined. Here, the authors show that glutamine metabolism and mTORC1 have two regulatory connections with relev
Externí odkaz:
https://doaj.org/article/4b6d4a30886f478a8c8fe16da840f895
Publikováno v:
Cancers, Vol 14, Iss 17, p 4129 (2022)
Cancer is a disease associated with aging, with patients over 70 accounting for 50% of newly diagnosed malignancies and 70% of all cancer deaths [...]
Externí odkaz:
https://doaj.org/article/d97a3f82b603484bb6e1e14576dd1938
Publikováno v:
Cancers, Vol 14, Iss 6, p 1386 (2022)
Therapeutic challenges regarding the population of elderly cancer patients and their heterogeneity lead to the need to implement person-centered approaches in order to optimize care strategies and adapt oncology treatments to each pattern of aging. T
Externí odkaz:
https://doaj.org/article/8730e9b2ec8944c6bfb3ae040936f226
Autor:
Florent Guerville, Isabelle Bourdel-Marchasson, Julie Déchanet-Merville, Isabelle Pellegrin, Pierre Soubeyran, Victor Appay, Maël Lemoine
Publikováno v:
Cancers, Vol 14, Iss 7, p 1622 (2022)
Aging is associated with chronic low-grade inflammation, cancer incidence and mortality. As inflammation contributes to cancer initiation and progression, one could hypothesize that age-associated chronic low-grade inflammation contributes to the inc
Externí odkaz:
https://doaj.org/article/61fa572b167845d0bf708eb78bc6fc12
Autor:
Petronella A. L. (Nelleke) Seghers, Jolina A. Kregting, Lieke H. van Huis-Tanja, Pierre Soubeyran, Shane O'Hanlon, Siri Rostoft, Marije E. Hamaker, Johanneke E. A. Portielje
Publikováno v:
Cancers, Vol 14, Iss 5, p 1123 (2022)
The treatment of cancer can have a significant impact on quality of life in older patients and this needs to be taken into account in decision making. However, quality of life can consist of many different components with varying importance between i
Externí odkaz:
https://doaj.org/article/3fe0adc20be04c3d89f41583a0cd1ceb
Autor:
Petronella A. L. (Nelleke) Seghers, Anke Wiersma, Suzanne Festen, Mariken E. Stegmann, Pierre Soubeyran, Siri Rostoft, Shane O’Hanlon, Johanneke E. A. Portielje, Marije E. Hamaker
Publikováno v:
Cancers, Vol 14, Iss 5, p 1147 (2022)
For physicians, it is important to know which treatment outcomes are prioritized overall by older patients with cancer, since this will help them to tailor the amount of information and treatment recommendations. Older patients might prioritize other
Externí odkaz:
https://doaj.org/article/feb85e4e5f8e469ea37e7c83d7e6f620
Autor:
Nadia Oubaya, Pierre Soubeyran, Nicoleta Reinald, Marianne Fonck, Mylène Allain, Sonia Zebachi, Damien Heitz, Marie Laurent, Cécile Delattre, Philippe Caillet, Jérôme Dauba, Sylvie Bastuji-Garin, Gilles Albrand, Michael Bringuier, Muriel Rainfray, Etienne Brain, Thomas Grellety, Elena Paillaud, Simone Mathoulin-Pélissier, Carine Bellera, Florence Canouï-Poitrine
Publikováno v:
Cancers, Vol 13, Iss 24, p 6154 (2021)
Background: The prognostic assessment of older cancer patients is complicated by their heterogeneity. We aimed to assess the prognostic value of routine inflammatory biomarkers. Methods: A pooled analysis of prospective multicenter cohorts of cancer
Externí odkaz:
https://doaj.org/article/141f339c33aa47b5a097736750cbb791
Autor:
Mélanie Dos Santos, Idlir Licaj, Carine Bellera, Laurent Cany, Giulia Binarelli, Pierre Soubeyran, Florence Joly
Publikováno v:
Cancers, Vol 13, Iss 24, p 6171 (2021)
Older cancer patients are vulnerable to chemotherapy-related cognitive impairment. We prospectively evaluated cognitive impairment and its predictive factors during first-line chemotherapy in elderly cancer patients (≥70 years). Cognitive function
Externí odkaz:
https://doaj.org/article/619252c84fac40ac8ceb1057dc0e9e8b