Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Pierre Sonigo"'
Autor:
Olivier Delelis, Vincent Parissi, Hervé Leh, Gladys Mbemba, Caroline Petit, Pierre Sonigo, Eric Deprez, Jean-François Mouscadet
Publikováno v:
PLoS ONE, Vol 2, Iss 7, p e608 (2007)
BACKGROUND: HIV-1 integrase (IN) catalyses the retroviral integration process, removing two nucleotides from each long terminal repeat and inserting the processed viral DNA into the target DNA. It is widely assumed that the strand transfer step has n
Externí odkaz:
https://doaj.org/article/22e2c5e08bc8405293a92f5115fcfafc
Publikováno v:
Virologie (Montrouge, France).
Publikováno v:
Journal of AOAC INTERNATIONAL. 92:1095-1104
iQ-Check E. coli O157:H7 (Bio-Rad Laboratories, Hercules, CA) is a real-time PCR kit for detection of E. coli O157:H7 from selected foods. Specific fluorescent oligonucleotide probes are used to detect target DNA during the amplification, by hybridiz
Autor:
Annick Lesne, Pierre Sonigo
Publikováno v:
Natures Sciences Sociétés. 15:53-56
Ce texte discute les enjeux des approches interdisciplinaires, par opposition a une specialisation accrue, face aux grandes questions de la biologie actuelle et aux defis que posent l'analyse et l'interpretation de donnees experimentales de plus en p
Publikováno v:
Journal of General Virology
Journal of General Virology, Microbiology Society, 2005, 86 (9), pp.2495-2506. ⟨10.1099/vir.0.80469-0⟩
Journal of General Virology, Microbiology Society, 2005, 86 (9), pp.2495-2506. ⟨10.1099/vir.0.80469-0⟩
Live-attenuated viruses have typically been generated from pathogenic viruses by genetic modifications that modified their replicative capacity. The present study investigated whether modification of the antigenic properties of live-attenuated viruse
Autor:
Pierre Sonigo
Publikováno v:
Current Sociology. 53:311-322
Biology has long been under the influence of the animal-machine metaphor. Today’s reference machine is no longer a clock but a robot. Accordingly, living cells are but individual parts in charge of the smooth functioning of the robot. Now, what if
Autor:
Audrey Brussel, Pierre Sonigo
Publikováno v:
Journal of Virology. 77:10119-10124
A novel Alu -long terminal repeat (LTR)-based real-time nested-PCR assay was developed to quantify integrated human immunodeficiency virus type 1 (HIV-1) DNA in infected cells with both accuracy and high sensitivity (six proviruses within 50,000 cell
Autor:
Jacques Leibowitch, Pierre Sonigo, Caroline Petit, Cyrille Barthélémy, Robert K. Naviaux, Dominique Mathez, Thierry Leste-Lasserre
Publikováno v:
Journal of Acquired Immune Deficiency Syndromes
Journal of Acquired Immune Deficiency Syndromes, Lippincott, Williams & Wilkins, 2003, 33 (4), pp.461-469. ⟨10.1097/00126334-200308010-00006⟩
Journal of Acquired Immune Deficiency Syndromes, Lippincott, Williams & Wilkins, 2003, 33 (4), pp.461-469. ⟨10.1097/00126334-200308010-00006⟩
To investigate the impact of antiretroviral treatment on the mitochondrial DNA (mtDNA) content of peripheral blood mononuclear cells (PBMCs) from HIV-1-infected patients.As absolute mtDNA copy numbers widely differ between individuals, we performed a
Autor:
Sophie Broche-Pierre, Audrey Brussel, Pierre Sonigo, Rémi Lancar, Dominique Mathez, Jacques Leibowitch, Thierry Calvez
Publikováno v:
AIDS. 17:645-652
Objective: To evaluate the potential use of 2-long terminal repeats (LTR) HIV circular DNA quantification for the monitoring of ongoing virus replication in treated HIV-1-infected patients. Design and methods: In a longitudinal setting, where the nat
Publikováno v:
Biochemical Journal. 358:505-510
Insertional mutagenesis of the Escherichia coli thymidylate synthase (TS) was used to address substrate recognition of HIV-1 protease in a well characterized structural context. By modifying the TS conformation while maintaining its enzymic activity,