Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Pierre Romero"'
Autor:
Pierre Romero, Laia Richart, Setareh Aflaki, Ambre Petitalot, Megan Burton, Audrey Michaud, Julien Masliah-Planchon, Frédérique Kuhnowski, Samuel Le Cam, Carlos Baliñas-Gavira, Céline Méaudre, Armelle Luscan, Abderaouf Hamza, Patricia Legoix, Anne Vincent-Salomon, Michel Wassef, Daniel Holoch, Raphaël Margueron
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Mutations in chromatin regulators are widespread in cancer. Among them, the histone H3 lysine 27 methyltransferase Polycomb Repressive Complex 2 (PRC2) shows distinct alterations according to tumor type. This specificity is poorly understood
Externí odkaz:
https://doaj.org/article/1b39f7921f8b45b382015dc3a19b069d
Publikováno v:
International Journal of Health Science. 2:2-8
Autor:
Pierre Romero, Laia Richart, Setareh Aflaki, Megan Burton, Audrey Michaud, Julien Masliah-Planchon, Frédérique Kuhnowski, Céline Méaudre, Armelle Luscan, Abderaouf Hamza, Patricia Legoix, Anne Vincent-Salomon, Michel Wassef, Daniel Holoch, Raphaël Margueron
Mutations in chromatin regulators or their histone substrates are widespread in cancer and often play decisive roles in tumorigenesis. These include Polycomb Repressive Complex 2 (PRC2), a histone H3 lysine 27 methyltransferase that shows distinct al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cccdbebd006a04c359ddf5872a66b82
https://doi.org/10.1101/2023.01.02.522460
https://doi.org/10.1101/2023.01.02.522460
Autor:
Elisabetta Marangoni, Elodie Manié, Nadège Gruel, Gaëtan MacGrogan, Ivan Bièche, Laetitia Fuhrmann, Cécile Laurent, Dominique Stoppa-Lyonnet, Marc-Henri Stern, Roman Rouzier, Caterina Marchiò, Jaydutt Bhalshankar, Pierre Romero, Sophie Vacher, Gabrielle Deniziaut, Fabien Reyal, Frédérique Berger, Tatiana Popova, Anne Vincent-Salomon, Vanessa Benhamo, Olivier Delattre
Publikováno v:
The American Journal of Pathology. 188:2378-2391
Medullary breast carcinoma (MBC) is a rare subtype of triple-negative breast cancer with specific genomic features within the spectrum of basal-like carcinoma (BLC). In this study of 19 MBCs and 36 non-MBC BLCs, we refined the transcriptomic and geno
Autor:
Céline Fargeas, Alain Beauchet, T. Clerici, Elisa Funck-Brentano, Ute Zimmermann, Iman Aouidad, Philippe Saiag, V. Chaussade, J.-F. Sei, Pierre Romero
Publikováno v:
Journal of The American Academy of Dermatology
Journal of The American Academy of Dermatology, Elsevier, 2019, 80, pp.1150-1152. ⟨10.1016/j.jaad.2018.10.036⟩
Journal of The American Academy of Dermatology, Elsevier, 2019, 80, pp.1150-1152. ⟨10.1016/j.jaad.2018.10.036⟩
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2856f79506c3dce992e070e193191a6b
https://hal.archives-ouvertes.fr/hal-03486720
https://hal.archives-ouvertes.fr/hal-03486720
Autor:
Michel Wassef, Pierre-Alexandre Just, Setareh Aflaki, H. Irem Baymaz, Anne Vincent-Salomon, Nicolas Servant, Raphaël Margueron, Sébastien Jacques, Michel Vidaud, Mikael Hivelin, Pascal W.T.C. Jansen, Margaret R. Wallace, Carole Kersouani, Eric Pasmant, Armelle Luscan, Dina Zielinski, Aude Battistella, Pierre Romero, Olivier Kosmider, Michiel Vermeulen
Publikováno v:
Proceedings of the National Academy of Sciences USA, 116, 13, pp. 6075-6080
Proceedings of the National Academy of Sciences USA, 116, 6075-6080
Proceedings of the National Academy of Sciences USA, 116, 6075-6080
Genetic mutations affecting chromatin modifiers are widespread in cancers. In malignant peripheral nerve sheath tumors (MPNSTs), Polycomb repressive complex 2 (PRC2), which plays a crucial role in gene silencing, is inactivated through recurrent muta
Autor:
Rania Farhat, Sara Jaber, Ali Shamseddine, Arafat Tfayli, Deborah K. Armstrong, Nagi S. El Saghir, Nathalie K. Zgheib, Firas Kreidieh, Stephanie Decousus, Hussein A. Assi, Georges Nemer, Nancy Uhrhammer, Raghid Charara, Yves-Jean Bignon, Jaber Abbas, Muhieddine Seoud, Ziad Salem, Katia E. Khoury, Yannick Bidet, Faek R. Jamali, Pierre Romero
Publikováno v:
The Oncologist. 20:357-364
Purpose. Breast cancer is the most common malignancy among women in Lebanon and in Arab countries, with 50% of cases presenting before the age of 50 years. Methods. Between 2009 and 2012, 250 Lebanese women with breast cancer who were considered to b
Autor:
Frédérique Penault-Llorca, Patricia Combes, Mathilde Gay-Bellile, Pierre Romero, Anne Cayre, Catherine Abrial, Philippe Vago, Yves-Jean Bignon, Shalini Singh, Fabrice Kwiatkowski, Maud Privat, Lauren Veronese, Andrei Tchirkov
Publikováno v:
Morphologie. 102:150-151
Introduction/Objectifs La dysfonction des telomeres, comme des mecanismes de reparation de l’ADN, joue un role majeur dans la progression tumorale. Nous avons etudie les parametres telomeriques et l’expression d’ERCC1, une proteine impliquee a
Autor:
Olivier Caron, David Malka, Audrey Remenieras, Bruno Buecher, Patrick R. Benusiglio, Camille Tlemsani, Mathilde Warcoin, Dominique Stoppa-Lyonnet, Qing Wang, Chystelle Colas, Jessica Moretta, Emmanuelle Mouret-Fourme, Pierre Romero, Martine Blayau, Sophie Grandjouan, Etienne Rouleau, Marina Di Maria, Nancy Uhrhammer, Antoine De Pauw, Catherine Noguès
Publikováno v:
Journal of Medical Genetics
Journal of Medical Genetics, BMJ Publishing Group, 2015, 52 (8), pp.563-565. ⟨10.1136/jmedgenet-2015-103153⟩
Journal of Medical Genetics, 2015, 52 (8), pp.563-565. ⟨10.1136/jmedgenet-2015-103153⟩
Journal of Medical Genetics, BMJ Publishing Group, 2015, 52 (8), pp.563-565. 〈10.1136/jmedgenet-2015-103153〉
Journal of Medical Genetics, BMJ Publishing Group, 2015, 52 (8), pp.563-565. ⟨10.1136/jmedgenet-2015-103153⟩
Journal of Medical Genetics, 2015, 52 (8), pp.563-565. ⟨10.1136/jmedgenet-2015-103153⟩
Journal of Medical Genetics, BMJ Publishing Group, 2015, 52 (8), pp.563-565. 〈10.1136/jmedgenet-2015-103153〉
The international, consensus testing criteria for CDH1 germline mutations were recently revised in order to increase their performances, particularly their sensitivity. It is paramount to identify a high proportion of actual mutation carriers, as fin
Autor:
Maud Privat, Andrei Tchirkov, Pierre Romero, Fabrice Kwiatkowski, Catherine Abrial, Lauren Veronese, Philippe Vago, Yves-Jean Bignon, Anne Cayre, Frédérique Penault-Llorca, Patricia Combes, Mathilde Gay-Bellile, Shalini Singh
Publikováno v:
Journal of Pathology: Clinical Research
Journal of Pathology: Clinical Research, Wiley Open Access, 2016, 2 (4), pp.234-246. ⟨10.1002/cjp2.52⟩
The Journal of Pathology: Clinical Research
Journal of Pathology: Clinical Research, Wiley Open Access, 2016, 2 (4), pp.234-246. ⟨10.1002/cjp2.52⟩
The Journal of Pathology: Clinical Research
International audience; Dysfunctional telomeres and DNA damage repair (DDR) play important roles in cancer progression. Studies have reported correlations between these factors and tumour aggressiveness and clinical outcome in breast cancer. We studi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e804fa39db8b5b9e44f73813912f399d
https://hal.archives-ouvertes.fr/hal-01675270
https://hal.archives-ouvertes.fr/hal-01675270