Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Pierre R Provost"'
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e111855 (2014)
MicroRNAs (miRNAs) are endogenous small non coding RNAs acting as negative regulators. miRNA are involved in lung development and pulmonary diseases. Measurement of their levels by qPCR is directly influenced by the stability of normalization gene(s)
Externí odkaz:
https://doaj.org/article/f54aebed12fd4ff299f0e406f07db1fa
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 168:102-109
21-hydroxylase is expressed in the developing lung where it is proposed as a local source of glucocorticoids playing important roles in lung development. We have studied the precise sites of Cyp21a1 expression in the developing mouse lung from the ps
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf77d68296738bd1bd17b94512787c7f
https://doi.org/10.1016/j.jsbmb.2017.02.009
https://doi.org/10.1016/j.jsbmb.2017.02.009
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 53:149-158
Automation of lung morphometric analysis is an asset in the study of lung pathophysiology because it is an assurance of robustness, reproducibility, and rapidity. The novel automated morphometric approach presented here meets these criteria. This new
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb91e7c9160afcd748bdc91f660c84f4
https://doi.org/10.1165/rcmb.2014-0469ma
https://doi.org/10.1165/rcmb.2014-0469ma
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 147:70-80
Glucocorticoids (GCs) are important regulators of lung development. The genes normally involved in GC synthesis in adrenals are co-expressed with 20α-hydroxysteroid dehydrogenase (20α-HSD) in the developing lung. In this study, C21-steroid metaboli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd93ac86066042283328b1557d71a026
https://doi.org/10.1016/j.jsbmb.2014.11.025
https://doi.org/10.1016/j.jsbmb.2014.11.025
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 183
Albeit their recognized negative effects on lung maturation, androgens have been proposed to play an essential positive role in lung development. This work aimed to evaluate the impact of blocking endogenous androgen and estrogen actions and to study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79e80c4499ec631574389cd97881b16f
https://pubmed.ncbi.nlm.nih.gov/29940312
https://pubmed.ncbi.nlm.nih.gov/29940312
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 122:295-301
17β-Hydroxysteroid dehydrogenase/17-ketosteroid reductase (17HSD/KSR) activity and 17HSD/KSR types 1, 2, 4, and 5 mRNA levels were characterized in ovarian cancer cell lines derived from patients unexposed to radiation or chemotherapy. Activity was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7188cc3113f8ed6e2b40bff5105f7e2e
https://doi.org/10.1016/j.jsbmb.2010.06.008
https://doi.org/10.1016/j.jsbmb.2010.06.008
Autor:
Yves Tremblay, Pierre R. Provost
Publikováno v:
Early Human Development. 86:529-534
Background Co-expression of four apolipoproteins with a sex difference was observed in the mouse developing lung with an increase during the day of the surge of surfactant synthesis and a causal relationship was proposed. Aims To determine whether th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da06c7e96114190d89fa8a5e4a797bd6
https://doi.org/10.1016/j.earlhumdev.2010.06.013
https://doi.org/10.1016/j.earlhumdev.2010.06.013
Publikováno v:
Molecular and Cellular Endocrinology. 319:79-87
Androgens delay fetal lung maturation through an androgen receptor (AR)-dependent mechanism. Type 2 and 5 17beta-hydroxysteroid dehydrogenases (17betaHSD) are involved in androgen inactivation and synthesis, respectively. We aimed to further characte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe2bf64cb82238ff2bc155353322a113
https://doi.org/10.1016/j.mce.2009.12.007
https://doi.org/10.1016/j.mce.2009.12.007
Publikováno v:
Lung. 188:229-233
Androgens and estrogens are known regulators of fetal and postnatal lung development, but their levels in the developing lung have never been determined. We present here, for the first time, a gas chromatography-mass spectrometry (GC/MS) quantificati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22a352b7ae48bf272f793cd094914dc0
https://doi.org/10.1007/s00408-010-9231-x
https://doi.org/10.1007/s00408-010-9231-x
Autor:
Pia Rantakari, Julie Plante, Pierre R. Provost, Marc Simard, Mélissa Côté, Yves Tremblay, Matti Poutanen
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 117:139-145
Many genes involved in the peripheral metabolism of androgens, including hydroxysteroid (17beta) dehydrogenases (HSD17B) 2 and 5, steroid 5alpha reductase 1, and 3alpha-HSD, are expressed in the developing lung. Because lung development is delayed by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6eb70064dc54bddf73ac19fc17cf5a1
https://doi.org/10.1016/j.jsbmb.2009.08.006
https://doi.org/10.1016/j.jsbmb.2009.08.006