Zobrazeno 1 - 10
of 191
pro vyhledávání: '"Pierre Olivier Fernagut"'
Autor:
Sarah Chevalier, Mélina Decourt, Maureen Francheteau, François Nicol, Anaïs Balbous, Pierre-Olivier Fernagut, Marianne Benoit-Marand
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Parkinson’s disease is characterized by the degeneration of substantia nigra pars compacta (SNc) dopaminergic neurons, leading to motor and cognitive symptoms. Numerous cellular and molecular adaptations following neurodegeneration or dopa
Externí odkaz:
https://doaj.org/article/90bd3bbde2cc4ab1a7edbdb46922720e
Autor:
Joanna Sikora, Sandra Dovero, Rémi Kinet, Marie-Laure Arotcarena, Sylvain Bohic, Erwan Bezard, Pierre-Olivier Fernagut, Benjamin Dehay
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract Lysosomal impairment is strongly implicated in Parkinson’s disease (PD). Among the several PD-linked genes, the ATP13A2 gene, associated with the PARK9 locus, encodes a transmembrane lysosomal P5-type ATPase. Mutations in the ATP13A2 gene
Externí odkaz:
https://doaj.org/article/bcad20ed2ad042cd96f98d940b76e28a
Autor:
Eloïse Van Camp, MSc, Christophe Rault, PhD, Quentin Heraud, RN, Jean-Pierre Frat, PhD, Anais Balbous, PhD, Arnaud W. Thille, PhD, Pierre-Olivier Fernagut, PhD, Xavier Drouot, PhD
Publikováno v:
Critical Care Explorations, Vol 5, Iss 12, p e1016 (2023)
OBJECTIVES:. It is well-established that sleep quality of ICU patients is poor, with sleep being highly fragmented by multiple awakenings. These sleep disruptions are associated with poor outcomes such as prolonged weaning duration from mechanical ve
Externí odkaz:
https://doaj.org/article/8ce0d8907e764fb0b2110aa8f6e54c8e
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S748- (2023)
Externí odkaz:
https://doaj.org/article/f7b6f368403844989d937eb1c71d3306
Autor:
Mélina Decourt, Eric Balado, Maureen Francheteau, Marcello Solinas, Marianne Benoît-Marand, Pierre-Olivier Fernagut
Publikováno v:
npj Parkinson's Disease, Vol 9, Iss 1, Pp 1-8 (2023)
Abstract Subtle cognitive impairment can occur early in the course of Parkinson’s disease (PD) and may manifest under different forms of executive dysfunction such as impaired cognitive flexibility. The precise contribution of nigrostriatal dopamin
Externí odkaz:
https://doaj.org/article/9d668e5e11c84054b68333eceb90fe76
Publikováno v:
npj Parkinson's Disease, Vol 7, Iss 1, Pp 1-8 (2021)
Abstract Impulse-control disorders are commonly observed during dopamine-replacement therapy in Parkinson’s disease, but the majority of patients seems “immune” to this side effect. Epidemiological evidence suggests that a major risk factor may
Externí odkaz:
https://doaj.org/article/6568bcc4d3d74378b5a605904e087140
Autor:
Marc Kermorgant, Pierre-Olivier Fernagut, Wassilios G. Meissner, Dina N. Arvanitis, Du N'Guyen, Jean-Michel Senard, Anne Pavy-Le Traon
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
Multiple system atrophy (MSA) is a rare and progressive neurodegenerative disorder. Autonomic failure (AF) is one main clinical feature which has a significant impact on health-related quality of life. The neuropathological hallmark of MSA is the abn
Externí odkaz:
https://doaj.org/article/12270e49d871457b953e494d3c20e6ce
A metabolic biomarker predicts Parkinson’s disease at the early stages in patients and animal models
Autor:
David Mallet, Thibault Dufourd, Mélina Decourt, Carole Carcenac, Paola Bossù, Laure Verlin, Pierre-Olivier Fernagut, Marianne Benoit-Marand, Gianfranco Spalletta, Emmanuel L. Barbier, Sebastien Carnicella, Véronique Sgambato, Florence Fauvelle, Sabrina Boulet
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 4 (2022)
Background Care management of Parkinson’s disease (PD) patients currently remains symptomatic, mainly because diagnosis relying on the expression of the cardinal motor symptoms is made too late. Earlier detection of PD therefore represents a key st
Externí odkaz:
https://doaj.org/article/09587078c22546ecb9d23f71bd52e432
Autor:
Xiuping Sun, Xuan Yu, Ling Zhang, Wenjie Zhao, Manshi Wang, Yu Zhang, Xianglei Li, Ran Gao, Ludivine S. Breger, Sandra Dovero, Gregory Porras, Pierre-Olivier Fernagut, Benjamin Dehay, Erwan Bezard, Chuan Qin
Publikováno v:
Heliyon, Vol 7, Iss 2, Pp e06302- (2021)
Woodchuck Hepatitis Virus Post-transcriptional Regulatory Element (WPRE) is thought to enhance transgene expression of target genes delivered by adeno-associated viral (AAV) vectors. This study assessed the protein expression of α-synuclein, phospho
Externí odkaz:
https://doaj.org/article/d5a145b2ed7a400cb6090ad578439dfd
Autor:
Mathieu Thabault, Valentine Turpin, Éric Balado, Cloé Fernandes‐Gomes, Anne‐Lise Huot, Anne Cantereau, Pierre‐Olivier Fernagut, Mohamed Jaber, Laurie Galvan
Publikováno v:
European Journal of Neuroscience. 57:607-618
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc013219da5cb806c5b0ff6e67517366
https://doi.org/10.1111/ejn.15919
https://doi.org/10.1111/ejn.15919