Laryngeal Abductor Function After Recurrent Laryngeal Nerve Injury in Cats

Autor: Pierre N.M. Konings, Hans F. Mahieu, Cees Groenhout, Robin J. Stolk, Jeroen A.D.M. Tonnaer, Julie T. van Lith-Bijl

Publikováno v: Archives of Otolaryngology - Head and Neck Surgery. 122:393-396

Objectives: To determine the influence of severity of neural injury of the recurrent laryngeal nerve on recovery of laryngeal abductor function and the importance of synkinesis. Design: The recovery of laryngeal abductor function was studied in 30 ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21c4a1d323d5f6cde60a80488d774780
https://doi.org/10.1001/archotol.1996.01890160035007

The use of macroporous microcarriers for the large-scale growth of V79 cells genetically designed to express single human cytochrome P450 isoenzymes and for the characterization of the expressed cytochrome P450

Autor: Rob C. A. Onderwater, Johannes Doehmer, R.M.E. Vos, A.R. Goeptar, Jan N. M. Commandeur, Piet R. Levering, Pierre N.M. Konings, Nico P. E. Vermeulen

Publikováno v: Protein Expression and Purification, 8, 439-446. Academic Press Inc.
Onderwater, R C A, Goeptar, A R, Levering, P R, Vos, R M, Konings, P N M, Doehmar, J, Commandeur, J N M & Vermeulen, N P E 1996, ' The use of macroporous microcarriers for the large-scale growth of V79 cells genetically designed to express single human cytochrome P450 isoenzymes and for the characterization of the expressed cytochrome P450. ', Protein Expression and Purification, vol. 8, pp. 439-446 . https://doi.org/10.1006/prep.1996.0122

In this study, macroporous microcarriers were used for the large-scale growth of parental V79 cells and V79 cells genetically engineered to express a single human cytochrome P4501A1 isoenzyme (V79h1A1). Starting from 2 x 10(5) cells/ml, approximately

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa81c3cebf587ede568fe5e31e581745
https://hdl.handle.net/1871/25449

α-Sialyl cholesterol increases laminin in Schwann cell cultures and attenuates cytostatic drug-induced reduction of laminin

Autor: Pierre N.M. Konings, Gé S.F. Ruigt, Veeneman Gerrit Herman, Ria L.A. Philipsen

Publikováno v: Brain Research. 654:118-128

Schwann cells play an important role in peripheral nerve regeneration. Here, we report the effect of alpha-sialyl cholesterol (alpha-SC), a derivative of the sialic acid-containing natural gangliosides, and the cytostatic agents, cisplatin, taxol and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b4aaefe4b265160f817309976bb9f19
https://doi.org/10.1016/0006-8993(94)91577-6

A specific enzyme assay for aminopeptidase M in rat brain

Autor: Terrence J. Gillespie, Thomas P. Davis, Bradley J. Merrill, Pierre N.M. Konings

Publikováno v: Life Sciences. 51:2097-2106

A specific enzyme assay for aminopeptidase M (APM) activity on rat brain membranes has been developed through selective use of enzyme inhibitors. Amastatin was the most potent inhibitor (amastatin > actinonin > MDL73347 > bestatin) for purified porci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::274749f385674e101984a2f6dc595ad3
https://doi.org/10.1016/0024-3205(92)90161-h

Selective laryngeal reinnervation with separate phrenic and ansa cervicalis nerve transfers

Autor: R. J. Stolk, J. T. Van Lith-Bijl, Jeroen A.D.M. Tonnaer, Hans F. Mahieu, C. Groenhout, Pierre N.M. Konings

Publikováno v: Archives of otolaryngology--headneck surgery. 123(4)

Objective: To perform selective reinnervation of the laryngeal abductor and adductor muscle groups after injury to the recurrent laryngeal nerve, recovering laryngeal function without impairment by synkinesis. Design: Ten cats underwent the surgical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18736ded9b094ba8d6b2c1f3d2bdbbe6
https://pubmed.ncbi.nlm.nih.gov/9109789