Výsledky vyhledávání - "Pierre N E, De Graan"

Akademický článek

Stress and Corticosteroids Aggravate Morphological Changes in the Dentate Gyrus after Early-Life Experimental Febrile Seizures in Mice

Autor: Jolien S. van Campen, Ellen V. S. Hessel, Kirsten Bohmbach, Giorgio Rizzi, Paul J. Lucassen, Sada Lakshmi Turimella, Eduardo H. L. Umeoka, Gideon F. Meerhoff, Kees P. J. Braun, Pierre N. E. de Graan, Marian Joëls

Publikováno v: Frontiers in Endocrinology, Vol 9 (2018)

Stress is the most frequently self-reported seizure precipitant in patients with epilepsy. Moreover, a relation between ear stress and epilepsy has been suggested. Although ear stress and stress hormones are known to influence seizure threshold in ro

Externí odkaz: https://doaj.org/article/cb2cd330eec9443cb441d84d3bce8e63

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Akademický článek

Expression Profiling after Prolonged Experimental Febrile Seizures in Mice Suggests Structural Remodeling in the Hippocampus.

Autor: Bart C Jongbloets, Koen L I van Gassen, Anne A Kan, Anneke H O Olde Engberink, Marina de Wit, Inge G Wolterink-Donselaar, Marian J A Groot Koerkamp, Onno van Nieuwenhuizen, Frank C P Holstege, Pierre N E de Graan

Publikováno v: PLoS ONE, Vol 10, Iss 12, p e0145247 (2015)

Febrile seizures are the most prevalent type of seizures among children up to 5 years of age (2-4% of Western-European children). Complex febrile seizures are associated with an increased risk to develop temporal lobe epilepsy. To investigate short-

Externí odkaz: https://doaj.org/article/080854a2caa24cb6a62a803239215788

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Akademický článek

Antenatal glucocorticoid treatment affects hippocampal development in mice.

Autor: Cornelle W Noorlander, Deodata Tijsseling, Ellen V S Hessel, Willem B de Vries, Jan B Derks, Gerard H A Visser, Pierre N E de Graan

Publikováno v: PLoS ONE, Vol 9, Iss 1, p e85671 (2014)

Synthetic glucocorticoids are administered to pregnant women at risk for preterm delivery, to enhance fetal lung maturation. The benefit of this treatment is well established, however caution is necessary because of possible unwanted side effects on

Externí odkaz: https://doaj.org/article/d052afa6ddad4a269abd285444b9e2fa

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Rapamycin-Sensitive Late-LTP is Enhanced in the Hippocampus of IL-6 Transgenic Mice

Autor: Anneke H. O. Olde Engberink, Donna L. Gruol, Ruben V. Hernandez, Pierre N. E. De Graan

Publikováno v: Neuroscience. 367:200-210

The neuroimmune factor IL-6 has been shown to regulate hippocampal long-term potentiation (LTP), an activity-dependent enhancement of synaptic transmission that plays a central role in memory and learning. This IL-6 action was demonstrated with relat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fccb86570af0d10fb593a717370f1525
https://doi.org/10.1016/j.neuroscience.2017.10.040

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Antagonizing Increased miR-135a Levels at the Chronic Stage of Experimental TLE Reduces Spontaneous Recurrent Seizures

Autor: R. Jeroen Pasterkamp, Gary P. Brennan, Stephanie Schorge, Tobias Engel, Peter C. van Rijen, Gareth Morris, Marina de Wit, Pierre N. E. De Graan, Vamshidhar R. Vangoor, Ketharini Senthilkumar, David C. Henshall, Roel Q.J. Schaapveld, Ronan M. Conroy, Cristina R. Reschke, Peter H. Gosselaar, Lieke L. van de Haar, Mark H. Broekhoven, Giuliano Giuliani

Publikováno v: The Journal of neuroscience : the official journal of the Society for Neuroscience, 39(26), 5064

Mesial temporal lobe epilepsy (mTLE) is a chronic neurological disease characterized by recurrent seizures. The antiepileptic drugs currently available to treat mTLE are ineffective in one-third of patients and lack disease-modifying effects. miRNAs,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::849cc1aeca23d5cc7a3f04f3ad3016f5
https://dspace.library.uu.nl/handle/1874/388126

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Hyperthermia-induced seizures followed by repetitive stress are associated with age-dependent changes in specific aspects of the mouse stress system

Autor: Pierre N. E. De Graan, Sada Lakshmi Turimella, Lívia Clemente Motta-Teixeira, Kees P.J. Braun, Jolien S. van Campen, Marian Joëls, Eduardo H.L. Umeoka, R. Angela Sarabdjitsingh, Norberto Garcia-Cairasco, Edward J. Robinson

Publikováno v: Journal of Neuroendocrinology, 31(4). Wiley-Blackwell
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Journal of Neuroendocrinology, 31(4):12697. Blackwell Publishing

Stress is among the most frequently self-reported factors provoking epileptic seizures in children and adults. It is still unclear, however, why some people display stress-sensitive seizures and others do not. Recently, we showed that young epilepsy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::125b1462f6f683ce346cc3c12421c7f2
https://dspace.library.uu.nl/handle/1874/387930

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Experimental febrile seizures impair interastrocytic gap junction coupling in juvenile mice

Autor: Dilaware Khan, Pierre N. E. De Graan, Christian Steinhäuser, Tushar Deshpande, Alexander Dupper, Peter Bedner

Publikováno v: Journal of Neuroscience Research. 94:804-813

Prolonged and focal febrile seizures (FSs) have been associated with the development of temporal lobe epilepsy (TLE), although the underlying mechanism and the contribution of predisposing risk factors are still poorly understood. Using a kainate mod

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d170a4eadaa4ee1536ab9f3a124bb921
https://doi.org/10.1002/jnr.23726

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