Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Pierre Moffatt"'
Autor:
Charline Mary, Aurélien Fouillen, Pierre Moffatt, Dainelys Guadarrama Bello, Rima M. Wazen, Daniel Grenier, Antonio Nanci
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract The mouth environment comprises the second most significant microbiome in the body, and its equilibrium is critical in oral health. Secretory calcium-binding phosphoprotein proline-glutamine rich 1 (SCPPPQ1), a protein normally produced by t
Externí odkaz:
https://doaj.org/article/bbd9f9fb9f13498090fe62b763722b26
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract The gingival seal around teeth prevents bacteria from destroying the tooth-supporting tissues and disseminating throughout the body. Porphyromonas gingivalis, a major periodontopathogen, degrades components of the specialized extracellular m
Externí odkaz:
https://doaj.org/article/3b9c7539470d449683391adf587afdfd
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184568 (2017)
BRIL (bone-restricted IFITM-like), is a short transmembrane protein expressed almost exclusively in osteoblasts. Although much is known about its bone-restricted gene expression pattern and protein biochemical and topological features, little informa
Externí odkaz:
https://doaj.org/article/e5356e414f2a48ab8fa6a7b46a689727
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
The gingival seal around teeth prevents bacteria from destroying the tooth-supporting tissues and disseminating throughout the body. Porphyromonas gingivalis, a major periodontopathogen, degrades components of the specialized extracellular matrix tha
Autor:
Pierre Moffatt, Aurélien Fouillen, Christian Baron, Jean Barbeau, Antonio Nanci, Daniel Grenier
Publikováno v:
European Journal of Oral Sciences
The junctional epithelium (JE) is a specialized portion of the gingiva that seals off the tooth‐supporting tissues from the oral environment. This relationship is achieved via a unique adhesive extracellular matrix that is, in fact, a specialized b
Autor:
Marie-Hélène Gaumond, Pierre Moffatt, Hideyo Yasuda, Latifa Aljebali, Prashant Kumar Jaiswal, Chun-Do Oh
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Scientific Reports
Scientific Reports
Snorc (Small NOvel Rich in Cartilage) has been identified as a chondrocyte-specific gene in the mouse. Yet little is known about the SNORC protein biochemical properties, and mechanistically how the gene is regulated transcriptionally in a tissue-spe
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 4; Pages: 2148
BRIL (bone restricted ifitm-like; also known as IFITM5) is a transmembrane protein expressed in osteoblasts. Although its role in skeletal development and homeostasis is unknown, mutations in BRIL result in rare dominant forms of osteogenesis imperfe
Autor:
Lisa Lamplugh, Yojiro Yamanaka, Pierre Moffatt, Bahareh Hekmatnejad, Marie-Hélène Gaumond, Frank Rauch, Yeqing Geng, Janice Penney
Publikováno v:
Bone. 107:131-142
Osteogenesis imperfecta (OI) type V is caused by an autosomal dominant mutation in the IFITM5 gene, also known as BRIL. The c.-14C>T mutation in the 5'UTR of BRIL creates a novel translational start site adding 5 residues (MALEP) in frame with the na
Publikováno v:
Bone. 148:115940
Osteogenesis imperfecta (OI) is a heritable connective tissue disorder that is most often caused by mutations in collagen type I encoding genes. Even though bone fragility is the most conspicuous finding in OI, the muscle system is also affected. In
Autor:
Antonio Nanci, Pierre Moffatt, Aurélien Fouillen, Christian Baron, Jean Barbeau, Daniel Grenier
Publikováno v:
The FASEB Journal. 33