Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Pierre Milbeo"'
Autor:
Nathan Picois, Yazid Boutahri, Pierre Milbeo, Chiara Zanato, Nathalie Lensen, Grégory Chaume, Thierry Brigaud
Publikováno v:
Molecules, Vol 29, Iss 6, p 1408 (2024)
Due to the specific properties provided by fluorine atoms to biomolecules, amino acids with fluorinated side chains are of great interest for medicinal chemistry and chemical biology. Among them, α-fluoroalkyl-α-amino acids constitute a unique clas
Externí odkaz:
https://doaj.org/article/95ff00e30329427b98b61726b9a106a5
Autor:
Pierre Milbeo, Arthur Lebrêne, Mariia Savchuk, Giang Vo-Thanh, Sylvain Oudeyer, Hélène Beucher, Jean-François Brière
Publikováno v:
Chemistry-A European Journal
Chemistry-A European Journal, In press, ⟨10.1002/chem.202301311⟩
Chemistry-A European Journal, In press, ⟨10.1002/chem.202301311⟩
International audience; A highly diastereoselective organocatalyzed domino Vinylogous sulfa-Michael-Aldol-Cyclocondensation (VMAC) reaction has been developed using alkylidene Meldrum’s acid as dienes highlighting two vinylogous steps, an unprecede
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e0e9146917e8d406e901118a481d5c2
https://hal-normandie-univ.archives-ouvertes.fr/hal-04102949/file/ChemEurJ2023.pdf
https://hal-normandie-univ.archives-ouvertes.fr/hal-04102949/file/ChemEurJ2023.pdf
Publikováno v:
Accounts of Chemical Research
Accounts of Chemical Research, American Chemical Society, 2021, 54 (3), pp.685-696. ⟨10.1021/acs.accounts.0c00680⟩
Accounts of Chemical Research, American Chemical Society, 2021, 54 (3), pp.685-696. ⟨10.1021/acs.accounts.0c00680⟩
International audience; The improvement of molecular diversity is one of the major concerns of chemists since the continuous development of original synthetic molecules provides unique scaffolds usable in organic and bioorganic chemistry. The challen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2178d66c6a5ebcf87bd4cec990323b91
https://doi.org/10.1021/acs.accounts.0c00680
https://doi.org/10.1021/acs.accounts.0c00680
Autor:
Lisa Pirrie, Fanny Tran, James H. Naismith, Yi Zhou, Oxana Kempf, Karl Kempf, Nicholas J. Westwood, Ganyuan Xiao, Jasmine Bickel, Magnus S. Alphey, Pierre Milbeo
Publikováno v:
Bioorganic & Medicinal Chemistry
Graphical abstract
The monosaccharide l-Rhamnose is an important component of bacterial cell walls. The first step in the l-rhamnose biosynthetic pathway is catalysed by glucose-1-phosphate thymidylyltransferase (RmlA), which condenses glucose-1
The monosaccharide l-Rhamnose is an important component of bacterial cell walls. The first step in the l-rhamnose biosynthetic pathway is catalysed by glucose-1-phosphate thymidylyltransferase (RmlA), which condenses glucose-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16ba6f6d600674db5e9739b5351e608c
http://europepmc.org/articles/PMC8613358
http://europepmc.org/articles/PMC8613358
Autor:
François Quintin, Laure Moulat, Xavier Bantreil, Monique Calmes, Claude Didierjean, Jean Martinez, Frédéric Lamaty, Pierre Milbeo
Publikováno v:
Tetrahedron Letters
Tetrahedron Letters, Elsevier, 2021, 63, pp.152706. ⟨10.1016/j.tetlet.2020.152706⟩
Tetrahedron Letters, Elsevier, 2021, 63, pp.152706. ⟨10.1016/j.tetlet.2020.152706⟩
International audience; (R)-1,2-Diaminobicyclo[2.2.2]octane was used as a starting material for the preparation, in solution or in a ball mill, of a salen ligand. Five metal salen complexes were prepared in high yield and their cytotoxic activities w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4c9bb2dac539f8da8ddb811ac3f7abc
https://hal.archives-ouvertes.fr/hal-03103305
https://hal.archives-ouvertes.fr/hal-03103305
Autor:
Jean Martinez, Baptiste Legrand, Claude Didierjean, Monique Calmes, Matthieu Simon, Muriel Amblard, Emmanuel Aubert, Emmanuel Wenger, Pierre Milbeo
Publikováno v:
Chemical Communications
Chemical Communications, Royal Society of Chemistry, 2020, 56 (57), pp.7921-7924. ⟨10.1039/d0cc02902e⟩
Chemical Communications, Royal Society of Chemistry, 2020, 56 (57), pp.7921-7924. ⟨10.1039/D0CC02902E⟩
Chemical Communications, Royal Society of Chemistry, 2020, 56 (57), pp.7921-7924. ⟨10.1039/d0cc02902e⟩
Chemical Communications, Royal Society of Chemistry, 2020, 56 (57), pp.7921-7924. ⟨10.1039/D0CC02902E⟩
International audience; The insertion of cyclic building blocks in oligoureas to stabilize or modulate the properties of the 12/14-helix was often fruitless. We herein propose a fully compatible highly constrained building block that could be incorpo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d043199124793d43909890a758f753f
https://hal.archives-ouvertes.fr/hal-03080580/document
https://hal.archives-ouvertes.fr/hal-03080580/document
Autor:
Jean Martinez, Claude Didierjean, Pierre Milbeo, Emmanuel Aubert, Laure Moulat, Monique Calmes
Publikováno v:
European Journal of Organic Chemistry. 2018:178-187
New chiral tetra- and bidentate ligands derived from the (R)-1,2-diaminobicyclo[2.2.2]octane scaffold have been synthesized and the influence of ligand N,N'-substituents on the catalytic activity of their corresponding copper(II) complexes toward nit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7780177e8ed9bc1763cba88693b9e09
https://doi.org/10.1002/ejoc.201701452
https://doi.org/10.1002/ejoc.201701452
Autor:
Baptiste Legrand, Muriel Amblard, Jean Martinez, Hongtao Liu, Pierre Milbeo, Monique Calmes, Emmanuel Wenger, Christophe André, Emmanuel Aubert, Matthieu Simon
Publikováno v:
Chemistry-A European Journal
Chemistry-A European Journal, Wiley-VCH Verlag, 2018, 24 (70), pp.18795-18800. ⟨10.1002/chem.201804404⟩
Chemistry-A European Journal, Wiley-VCH Verlag, 2018, 24 (70), pp.18795-18800. ⟨10.1002/chem.201804404⟩
12/10-Helices constitute suitable templates that can be used to design original structures. Nevertheless, they often suffer from a weak stability in polar solvents because they exhibit a mixed hydrogen-bond network resulting in a small macrodipole. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98ea85080c7b0fccb1958dd18ebd9022
https://hal.archives-ouvertes.fr/hal-02403147
https://hal.archives-ouvertes.fr/hal-02403147
Autor:
Jean Martinez, Claude Didierjean, Pierre Milbeo, Monique Calmes, Emmanuel Aubert, Laure Moulat
Publikováno v:
Journal of Organic Chemistry
Journal of Organic Chemistry, American Chemical Society, 2017, 82 (6), pp.3144-3151. ⟨10.1021/acs.joc.7b00122⟩
Journal of Organic Chemistry, American Chemical Society, 2017, 82 (6), pp.3144-3151. ⟨10.1021/acs.joc.7b00122⟩
The synthesis of enantiopure 1,2-diaminobicyclo[2.2.2]octane (DABO, 1) and its two selectively N-Boc monoprotected derivatives 15 and 16 is described. Starting from bicyclic β-amino acid 3 or 5, strategies involving Curtius and Hofmann rearrangement
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8e7a3c4203a82c644d3aad27f03ba46
https://hal.archives-ouvertes.fr/hal-01552321
https://hal.archives-ouvertes.fr/hal-01552321
Autor:
Pierre, Milbeo, Laure, Moulat, Claude, Didierjean, Emmanuel, Aubert, Jean, Martinez, Monique, Calmès
Publikováno v:
The Journal of organic chemistry. 82(6)
The synthesis of enantiopure 1,2-diaminobicyclo[2.2.2]octane (DABO, 1) and its two selectively N-Boc monoprotected derivatives 15 and 16 is described. Starting from bicyclic β-amino acid 3 or 5, strategies involving Curtius and Hofmann rearrangement
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fc394f427407df8af066058c0b7305f5
https://pubmed.ncbi.nlm.nih.gov/28198182
https://pubmed.ncbi.nlm.nih.gov/28198182