Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Pierre Mainil-Varlet"'
Publikováno v:
Cartilage
Objective This study aimed to test the hypothesis that administration of increasing doses of Sinovial (hyaluronic acid [HA]), would exhibit a dose-dependent effect on the prevention of cartilage degradation, without local and systemic toxicity. Metho
Autor:
Pierre Mainil-Varlet, Antonella Schiavinato, A. Decambron, Caroline Aschinger, Atsuya Watanabe
Publikováno v:
Bio-Medical Materials and Engineering. 30:403-417
BACKGROUND Various biomaterials/technologies have been tested for treatment of intervertebral disc (IVD) degeneration (IDD). Only few non-surgical options exist. OBJECTIVE Assessment of efficacy and safety of the hyaluronic acid derivative hydrogel H
Autor:
Dobrila Nesic, Pierre Mainil-Varlet, Henriette Jülke, Birgit Schäfer, Roland Jakob, Walter Brehm
Publikováno v:
Cartilage
Objective: Successful repair of defects in the avascular zone of meniscus remains a challenge in orthopedics. This proof of concept study aimed to investigate a guided tissue regeneration approach for treatment of tears in meniscus avascular zone in
Autor:
Martin Jung, Tobias Gotterbarm, Simona Berardi Vilei, Wiltrud Richter, Steffen J. Breusch, Pierre Mainil-Varlet
Publikováno v:
International Orthopaedics. 37:1171-1178
The purpose of this study was to examine the effect of subperiosteal injection of chondroinductive growth factors on the histological and biomechanical outcome of autologous osteoperiosteal grafts.Thirty six standardised osteochondral defects were cr
Autor:
Roger R. Dmochowski, Eric Rambeaux, Christophe Aubert, Pierre Mainil-Varlet, Hélène Combrisson, Rostand Mitouassiwou, Pierre Costa, Pomme Boissier
Publikováno v:
Journal of Urology. 195
Publikováno v:
CARTILAGE. 4:28-41
Objective: To test the efficacy of a hyaluronan derivative (HYADD®4-G) in a model of osteoarthritis (anterior cruciate ligament [ACLT]) and to compare its efficacy with the injection of growth factors. Design: In a first experimental set-up, special
Autor:
Michael D. Buschmann, C. Wayne McIlwraith, Robert A. Whiteside, Robert L. Sah, Lisa A. Fortier, Caroline D. Hoemann, Pierre Mainil-Varlet, Mark Hurtig, Jukka S. Jurvelin, Ernst B. Hunziker
Publikováno v:
CARTILAGE. 2:137-152
Investigational devices for articular cartilage repair or replacement are considered to be significant risk devices by regulatory bodies. Therefore animal models are needed to provide proof of efficacy and safety prior to clinical testing. The financ
Autor:
Harish S. Hosalkar, Andreas Krueger, Pierre Mainil-Varlet, Sandro Kohl, Lorenz Buechler, Klaus A. Siebenrock
Publikováno v:
HIP International. 21:154-162
This prospective study on symptomatic adult patients with femoroacetabular impingement (FAI) who underwent open surgical intervention for management was designed to identify any obvious histological differences in the damaged acetabular cartilage wit
Autor:
Paul F. Heini, Pierre Mainil-Varlet, Jose Diaz-Romero, Thomas Aigner, S. Giovannini, Dobrila Nesic
Publikováno v:
Europe PubMed Central
European Cells & Materials, Vol 20, Pp 245-259 (2010)
European Cells & Materials, Vol 20, Pp 245-259 (2010)
Cell therapies for articular cartilage defects rely on expanded chondrocytes. Mesenchymal stem cells (MSC) represent an alternative cell source should their hypertrophic differentiation pathway be prevented. Possible cellular instruction between huma
Publikováno v:
Osteoarthritis and Cartilage. 26:S422