Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Pierre M. Bodelle"'
Autor:
Eric R. Goedken, Maria A. Argiriadi, Justin D. Dietrich, Andrew M. Petros, Navasona Krishnan, Sanjay C. Panchal, Wei Qiu, Haihong Wu, Haizhong Zhu, Ashley M. Adams, Pierre M. Bodelle, Lucas Goguen, Paul L. Richardson, Peter F. Slivka, Myron Srikumaran, Anup K. Upadhyay, Bainan Wu, Russell A. Judge, Anil Vasudevan, Sujatha M. Gopalakrishnan, Philip B. Cox, Vincent S. Stoll, Chaohong Sun
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Anti-IL17A therapies have proven effective for numerous inflammatory diseases including psoriasis, axial spondylitis and psoriatic arthritis. Modulating and/or antagonizing protein–protein interactions of IL17A cytokine binding to its cell
Externí odkaz:
https://doaj.org/article/73a129f16e244becaaa09ce714e81a66
Autor:
Anup K. Upadhyay, Ron Pithawalla, Rodger F. Henry, Russell A. Judge, Chaohong Sun, Justin A. Simanis, Leiming Li, Violeta L. Marin, Andrew M. Petros, Pierre M. Bodelle
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 28:1708-1713
The tandem TUDOR domains present in the non-catalytic C-terminal half of the KDM4A, 4B and 4C enzymes play important roles in regulating their chromatin localizations and substrate specificities. They achieve this regulatory role by binding to differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eb7dcb63ded0bdffc7ddcc0ad4e291a
https://doi.org/10.1016/j.bmcl.2018.04.050
https://doi.org/10.1016/j.bmcl.2018.04.050
Autor:
Andrew M. Petros, Alla Korepanova, Clarissa G. Jakob, Wei Qiu, Sanjay C. Panchal, Jie Wang, Justin D. Dietrich, Jason T. Brewer, Frauke Pohlki, Andreas Kling, Kyle Wilcox, Viktor Lakics, Lamiaa Bahnassawy, Peter Reinhardt, Sarathy Karunan Partha, Pierre M. Bodelle, Marc Lake, Erik I. Charych, Vincent S. Stoll, Chaohong Sun, Eric G. Mohler
Publikováno v:
Journal of medicinal chemistry. 62(8)
Apolipoprotein E is a 299-residue lipid carrier protein produced in both the liver and the brain. The protein has three major isoforms denoted apoE2, apoE3, and apoE4 which differ at positions 112 and 158 and which occur at different frequencies in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::353512c6397009fb6a0711d678d2c1aa
https://pubmed.ncbi.nlm.nih.gov/30933499
https://pubmed.ncbi.nlm.nih.gov/30933499
Autor:
Violeta L. Marin, Wenyu Yu, William N. Pappano, Peter Brown, Fengling Li, Masoud Vedadi, Charles W. Hutchins, Andrew M. Petros, Maricel Torrent, Chaohong Sun, Haizhong Zhu, Anup K. Upadhyay, Pierre M. Bodelle, Russell A. Judge
Publikováno v:
ACS Medicinal Chemistry Letters. 7:1102-1106
SETD8 is a histone H4–K20 methyltransferase that plays an essential role in the maintenance of genomic integrity during mitosis and in DNA damage repair, making it an intriguing target for cancer research. While some small molecule inhibitors for S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::768047a77724c668da15da1e2b409585
https://doi.org/10.1021/acsmedchemlett.6b00303
https://doi.org/10.1021/acsmedchemlett.6b00303