Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Pierre M Jean Beltran"'
A bidirectional switch in the Shank3 phosphorylation state biases synapses toward up- or downscaling
Autor:
Chi-Hong Wu, Vedakumar Tatavarty, Pierre M Jean Beltran, Andrea A Guerrero, Hasmik Keshishian, Karsten Krug, Melanie A MacMullan, Li Li, Steven A Carr, Jeffrey R Cottrell, Gina G Turrigiano
Publikováno v:
eLife, Vol 11 (2022)
Homeostatic synaptic plasticity requires widespread remodeling of synaptic signaling and scaffolding networks, but the role of post-translational modifications in this process has not been systematically studied. Using deep-scale quantitative analysi
Externí odkaz:
https://doaj.org/article/62dee5cecd974444b9a59db1da6ab44d
Autor:
Hasmik Keshishian, E Robert McDonald III, Filip Mundt, Randy Melanson, Karsten Krug, Dale A Porter, Luke Wallace, Dominique Forestier, Bokang Rabasha, Sara E Marlow, Judit Jane‐Valbuena, Ellen Todres, Harrison Specht, Margaret Lea Robinson, Pierre M Jean Beltran, Ozgun Babur, Meagan E Olive, Javad Golji, Eric Kuhn, Michael Burgess, Melanie A MacMullan, Tomas Rejtar, Karen Wang, DR Mani, Shankha Satpathy, Michael A Gillette, William R Sellers, Steven A Carr
Publikováno v:
Molecular Systems Biology, Vol 17, Iss 9, Pp n/a-n/a (2021)
Abstract Reliable methods to quantify dynamic signaling changes across diverse pathways are needed to better understand the effects of disease and drug treatment in cells and tissues but are presently lacking. Here, we present SigPath, a targeted mas
Externí odkaz:
https://doaj.org/article/8c21ac714ff142d89c9c58dde8847a35
Publikováno v:
Molecular Systems Biology, Vol 13, Iss 3, Pp n/a-n/a (2017)
Abstract Organisms are constantly exposed to microbial pathogens in their environments. When a pathogen meets its host, a series of intricate intracellular interactions shape the outcome of the infection. The understanding of these host–pathogen in
Externí odkaz:
https://doaj.org/article/6c455065c05848b381b70b51e4d942d5
Autor:
Jeremy M. Robbins, Prashant Rao, Shuliang Deng, Michelle J. Keyes, Usman A. Tahir, Daniel H. Katz, Pierre M. Jean Beltran, François Marchildon, Jacob L. Barber, Bennet Peterson, Yan Gao, Adolfo Correa, James G. Wilson, J. Gustav Smith, Paul Cohen, Robert Ross, Claude Bouchard, Mark A. Sarzynski, Robert E. Gerszten
Publikováno v:
JCI Insight. 8
Autor:
Benjamin L. Ebert, Steven A. Carr, Philip P. Chamberlain, Mark Rolfe, Jean-Michel Cayuela, Jean-Jacques Kiladjian, Stéphane De Botton, Véronique Saada, Christophe Marzac, Sophie Cotteret, Rob S. Sellar, Andrew A. Guirguis, Alexander Tepper, Kaushik Viswanathan, Marie McConkey, Thomas Clayton, Mary E. Matyskiela, Namrata D. Udeshi, Pierre M. Jean Beltran, Daniel E. Grinshpun, Jessica A. Gasser, Aline Renneville
Supplementary Methods, Figures, and Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b08d3edb19dfbd0f47523bcd0445d5d1
https://doi.org/10.1158/2643-3230.22543713.v1
https://doi.org/10.1158/2643-3230.22543713.v1
Autor:
Benjamin L. Ebert, Steven A. Carr, Philip P. Chamberlain, Mark Rolfe, Jean-Michel Cayuela, Jean-Jacques Kiladjian, Stéphane De Botton, Véronique Saada, Christophe Marzac, Sophie Cotteret, Rob S. Sellar, Andrew A. Guirguis, Alexander Tepper, Kaushik Viswanathan, Marie McConkey, Thomas Clayton, Mary E. Matyskiela, Namrata D. Udeshi, Pierre M. Jean Beltran, Daniel E. Grinshpun, Jessica A. Gasser, Aline Renneville
Thalidomide analogues exert their therapeutic effects by binding to the CRL4CRBN E3 ubiquitin ligase, promoting ubiquitination and subsequent proteasomal degradation of specific protein substrates. Drug-induced degradation of IKZF1 and IKZF3 in B-cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57eb4d478e4fdb51c5ac5ce49a6e60d1
https://doi.org/10.1158/2643-3230.c.6550374.v1
https://doi.org/10.1158/2643-3230.c.6550374.v1
Autor:
Benjamin L. Ebert, Steven A. Carr, Philip P. Chamberlain, Mark Rolfe, Jean-Michel Cayuela, Jean-Jacques Kiladjian, Stéphane De Botton, Véronique Saada, Christophe Marzac, Sophie Cotteret, Rob S. Sellar, Andrew A. Guirguis, Alexander Tepper, Kaushik Viswanathan, Marie McConkey, Thomas Clayton, Mary E. Matyskiela, Namrata D. Udeshi, Pierre M. Jean Beltran, Daniel E. Grinshpun, Jessica A. Gasser, Aline Renneville
Supplementary Table 1. Proteomic data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::680350b5736d467704658c272205ed4c
https://doi.org/10.1158/2643-3230.22543710.v1
https://doi.org/10.1158/2643-3230.22543710.v1
Autor:
Daniel H. Katz, Robert E. Gerszten, Lori L. Jennings, Changyu Shen, Theresa Margarethe Rienmüller, Christian Baumgartner, Claude Bouchard, Mark A. Sarzynski, Jacob L. Barber, Pierre M. Jean Beltran, Michelle J. Keyes, Daniela Schranner, Sujoy Ghosh, Robert Ross, Bennet Peterson, Usman A. Tahir, Jeremy M. Robbins, Shuliang Deng, Steven A. Carr
Publikováno v:
Nat Metab
Maximal oxygen uptake (VO2max) is a direct measure of human cardiorespiratory fitness and is associated with health. However, the molecular determinants of interindividual differences in baseline (intrinsic) VO2max, and of increases of VO2max in resp
Autor:
Pierre M Jean Beltran, Vedakumar Tatavarty, Chi-Hong Wu, Andrea A Guerrero, Hasmik Keshishian, Karsten Krug, Melanie A MacMullan, Li Li, Steven A Carr, Jeffrey R Cottrell, Gina G Turrigiano
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a34af56790b690b5fb058ed02112be07
https://doi.org/10.7554/elife.74277.sa2
https://doi.org/10.7554/elife.74277.sa2
Autor:
John C. Boothroyd, Tess C. Branon, Steven A. Carr, Alice Y. Ting, Alicja M. Cygan, Alma G. Mendoza, Pierre M. Jean Beltran
Publikováno v:
mBio, Vol 12, Iss 6 (2021)
Toxoplasma gondii is a ubiquitous, intracellular parasite that envelops its parasitophorous vacuole with a protein-laden membrane (PVM). The PVM is critical for interactions with the infected host cell, such as nutrient transport and immune defense.