Zobrazeno 1 - 10 of 25 pro vyhledávání: '"Pierre Lefrancier"'
1
SYNTHESIS OF N-ACETYL-MURAMYL-L-ALANYL-D-ISOGLUTAMINE, AN ADJUVANT OF THE IMMUNE RESPONSE, AND OF SOME N-ACETYL-MURAMYL-PEPTIDE ANALOGS
Autor: M. Derrien, I. Lederman, J. Choay, Pierre Lefrancier
Publikováno v: International Journal of Peptide and Protein Research. 9:249-257
A relatively easy synthetic method is reported for the production of the immunoadjuvant glycopeptide, N-acetyl-muramyl-L-alanyl-D-isoglutamine (MDP). Most of the details in this method were also applied to the preparation of some analogs, that were s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2c249cdb96cbd33a90cbdddb44787b3
https://doi.org/10.1111/j.1399-3011.1977.tb03488.x
Zobrazit plný text záznamu
2
Enhancement by muramyl peptides of the protective response of interferon-alpha/beta against encephalomyocarditis virus infection
Autor: George M. Bahr, Louis Chedid, Philippe Pouillart, Francoise Audibert, Pierre Lefrancier
Publikováno v: International journal of immunopharmacology. 18(3)
The use of interferon-alpha (IFN-alpha) in the treatment of infectious diseases has shown limited efficacy and dose-limiting toxicity. We have selected safe immunomodulators of the muramyl peptide family with the potential of enhancing the efficacy o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::233de1af3409f3b93ec4d4ff37687665
https://pubmed.ncbi.nlm.nih.gov/8796446
Zobrazit plný text záznamu
5
In Vivo and in Vitro Stimulation of Nonspecific Immunity by the -D-p-Aminophenyl Glycoside of N-Acetylmuramyl-L-Alanyl-D-Isoglutamine and an Oligomer Prepared by Cross-Linking with Glutaraldehyde
Autor: Edgar Sathe, Chantal Damais, Jean Choay, Monique Parant, Louis Chedid, Francine Parant, Pierre Lefrancier, E Lederer, Francoise Audibert
Publikováno v: Journal of Infectious Diseases. 138:378-386
Several biological activities of N-acetylmuramyl-L-alanyl-D-isoglutamine (MDP for muramyl dipeptide), a synthetic immunoadjuvant, are inhibited after glycosidation with p-aminophenol. Thus, this glycoside does not induce an increase humoral antibody
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaf4a2c8a0e3d599c65216ac681d9b59
https://doi.org/10.1093/infdis/138.3.378
Zobrazit plný text záznamu
6
Muramyl peptides. Variation of somnogenic activity with structure
Autor: Jean Choay, Edgar Lederer, Manfred L. Karnovsky, James M. Walter, Louis Chedid, James M. Krueger, Pierre Lefrancier
Publikováno v: The Journal of Experimental Medicine
Sleep-promoting activities of muramyl dipeptide (MDP) (NAc-Mur-L-ala-D-isogln) and the naturally occurring muramyl peptide(s), factor S, have recently been demonstrated. We now have amplified our understanding of structural requirements for somnogeni
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21c83a265384ad25a3670eeb8853f627
https://doi.org/10.1084/jem.159.1.68
Zobrazit plný text záznamu
8
Modulation of the immune response by a synthetic adjuvant and analogs
Autor: Jean Choay, Edgar Lederer, Francoise Audibert, Pierre Lefrancier, Louis Chedid
Publikováno v: Proceedings of the National Academy of Sciences. 73:2472-2475
N-Acetylmuramyl-L-alanyl-D-isoglutamine increases the humoral immune response of mice when given in aqueous media instead of the usual water-in-oil emulsions. Moreover, this compound is adjuvant active even by the oral route. In view of studying the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f93274db32f81320381914cb56c77f3
https://doi.org/10.1073/pnas.73.7.2472
Zobrazit plný text záznamu
9
Dissociation of immunostimulant activities of muramyl dipeptide (MDP) by linking amino-acids or peptides to the glutaminyl residue
Autor: C. Damais, Pierre Lefrancier, Jean Choay, Francoise Audibert, Louis Chedid, M. Parant, M. Derrien
Publikováno v: Biochemical and Biophysical Research Communications. 96:915-923
N-acetyl-muramyl-L-alanyl-D-isoglutamine (muramyl dipeptide or MDP) is the minimal structure required for substituting mycobacteria in Freund's complete adjuvant. It is an adjuvant when injected in saline, protects mice non-specifically against infec
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef6c13f2b56d12523ea23ec8fcf4afbb
https://doi.org/10.1016/0006-291x(80)91442-4
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje