Zobrazeno 1 - 10 of 31 pro vyhledávání: '"Pierre Lavallee"'
2
Characterization of the Binding Site for Inhibitors of the HPV11 E1−E2 Protein Interaction on the E2 Transactivation Domain by Photoaffinity Labeling and Mass Spectrometry
Autor: David M Hambly, Christiane Yoakim, Peter W. White, Jerry L. Hopkins, Jacques Archambault, Graham A. McGibbon, William W. Ogilvie, Ingrid Guse, Walter Davidson, Lee Frego, Pierre Lavallee
Publikováno v: Analytical Chemistry. 76:2095-2102
An indandione-containing class of inhibitors abrogates DNA replication of human papillomavirus (HPV) types 6 and 11 by binding reversibly to the transactivation domain (TAD) of the viral E2 protein and inhibiting its interaction with the viral E1 hel
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c1875149eded3b7f2d1b40b1dcf6aaa
https://doi.org/10.1021/ac035335o
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4
Practical Synthesis of BILA 2157 BS, a Potent and Orally Active Renin Inhibitor: Use of an Enzyme-Catalyzed Hydrolysis for the Preparation of Homochiral Succinic Acid Derivatives
Autor: Pierre Lavallee, Dominik Wernic, Jean-Simon Duceppe, Pierre L. Beaulieu, James Gillard, Christian Beaulieu, Murray D. Bailey
Publikováno v: The Journal of Organic Chemistry. 64:6622-6634
We have developed a highly convergent and stereoselective synthesis of BILA 2157 BS, a potent and orally active renin inhibitor. The synthesis proceeds in 15 distinct chemical steps (with several integrated, multistep operations) from aminodiol 4. Th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f143d3e8b06189163aa764156b3305c9
https://doi.org/10.1021/jo990321x
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5
Practical, Stereoselective Synthesis of Palinavir, a Potent HIV Protease Inhibitor
Autor: Jean-Simon Duceppe, Louis Plamondon, Yvan Guindon, Colette Boucher, Ingrid Guse, Serge Valois, Pierre L. Beaulieu, Christiane Yoakim, Yves Bousquet, and Dominik Wernic, Pierre Lavallee, Francois Soucy, Louis Grenier, James Gillard, A. Abraham, Chantal Grand-Maître, Paul C. Anderson, Vida Gorys
Publikováno v: The Journal of Organic Chemistry. 62:3440-3448
Palinavir is a potent peptidomimetic-based HIV protease inhibitor. We have developed a highly convergent and stereoselective synthesis which is amenable to the preparation of multikilogram quantities of this compound. The synthetic sequence proceeds
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4873199e1c916b6311bf211b9a80ea03
https://doi.org/10.1021/jo9702655
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7
Elektronická kniha
Pratiques et méthodes de sondage
Autor: Marie-Eve Tremblay, Pierre Lavallée
Le sondage est devenu un outil indispensable à l'observateur de la vie contemporaine: il fournit une base méthodologique solide pour établir le portrait d'une population ou pour appréhender les facettes d'une situation complexe. Mais les modalit
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Plný text Recenzováno Digitální knihovna AV ČR
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