Zobrazeno 1 - 10
of 811
pro vyhledávání: '"Pierre Laurent‐Puig"'
Autor:
Sophie Mouillet-Richard, Angélique Gougelet, Bruno Passet, Camille Brochard, Delphine Le Corre, Caterina Luana Pitasi, Camille Joubel, Marine Sroussi, Claire Gallois, Julien Lavergne, Johan Castille, Marthe Vilotte, Nathalie Daniel-Carlier, Camilla Pilati, Aurélien de Reyniès, Fatima Djouadi, Sabine Colnot, Thierry André, Julien Taieb, Jean-Luc Vilotte, Béatrice Romagnolo, Pierre Laurent-Puig
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Background The mesenchymal subtype of colorectal cancer (CRC), associated with poor prognosis, is characterized by abundant expression of the cellular prion protein PrPC, which represents a candidate therapeutic target. How PrPC is induced i
Externí odkaz:
https://doaj.org/article/6c482fe7bb844cb5b3a5a20ec371350b
Autor:
Geoffroy Poulet, Jean-Sébastien Hulot, Anne Blanchard, Damien Bergerot, Wenjin Xiao, Frederic Ginot, Audrey Boutonnet-Rodat, Abdelli Justine, Guillaume Beinse, Vanna Geromel, Laurence Pellegrina, Michel Azizi, Pierre Laurent-Puig, Leonor Benhaim, Valerie Taly
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract In the last decade, clinical studies have investigated the clinical relevance of circulating cell-free-DNA (ccfDNA) as a diagnostic and prognosis tool in various diseases including cancers. However, limited knowledge on ccfDNA biology restra
Externí odkaz:
https://doaj.org/article/1023306ad2ac4a30b7b4267a107f21d3
Autor:
Jean Bastin, Marine Sroussi, Ivan Nemazanyy, Pierre Laurent-Puig, Sophie Mouillet-Richard, Fatima Djouadi
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background Colorectal cancer (CRC) can be classified into four molecular subtypes (CMS) among which CMS1 is associated with the best prognosis, while CMS4, the mesenchymal subtype, has the worst outcome. Although mitochondria are considered
Externí odkaz:
https://doaj.org/article/08da4395fe2b4e27ba67cb17740e7c9b
Autor:
Simon Garinet, Audrey Didelot, Laetitia Marisa, Guillaume Beinse, Marine Sroussi, Françoise Le Pimpec-Barthes, Elizabeth Fabre, Laure Gibault, Pierre Laurent-Puig, Sophie Mouillet-Richard, Antoine Legras, Hélène Blons
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-12 (2023)
Abstract Background In Lung adenocarcinoma (LUAD), targeted therapies and immunotherapies have moved from metastatic to early stage and stratification of the relapse risk becomes mandatory. Here we identified a miR-200 based RNA signature that deline
Externí odkaz:
https://doaj.org/article/904733005c644c07940174895ea01e79
Autor:
Julia Källberg, Alexandra Harrison, Valerie March, Santa Bērziņa, Ivan Nemazanyy, Oliver Kepp, Guido Kroemer, Sophie Mouillet-Richard, Pierre Laurent-Puig, Valérie Taly, Wenjin Xiao
Publikováno v:
Cell Death and Disease, Vol 14, Iss 5, Pp 1-12 (2023)
Abstract The major underlying cause for the high mortality rate in colorectal cancer (CRC) relies on its drug resistance, to which intratumor heterogeneity (ITH) contributes substantially. CRC tumors have been reported to comprise heterogeneous popul
Externí odkaz:
https://doaj.org/article/f3c2f693a1da46e99b45f5f98c739dd7
Autor:
Carlos Lopez-Otin, Christophe Klein, Chantal Desdouets, Guido Kroemer, Pierre Laurent-Puig, Jonathan Pol, Sophie Mouillet-Richard, Gautier Stoll, Isabelle Martins, Maria Perez-Lanzon, Vincent Carbonnier, Pierre Cordier, Fatima Domenica Elisa De Palma, Adriana Petrazzuolo, Floriane Arbaretaz, Khady Mangane, Helene Fohrer Ting, Juliette Paillet, Delphine Le Corre, Wenjjin Xiao, Marine Sroussi, Maria Chiara Maiuri
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 6 (2023)
Background Progress in breast cancer (BC) research relies on the availability of suitable cell lines that can be implanted in immunocompetent laboratory mice. The best studied mouse strain, C57BL/6, is also the only one for which multiple genetic var
Externí odkaz:
https://doaj.org/article/57aae1981bde44aba4b44c6f135bd53d
Autor:
Maximiliano Gelli, Christophe Desterke, Mohamed Amine Bani, Valérie Boige, Charles Ferté, Peggy Dartigues, Bastien Job, Geraldine Perkins, Pierre Laurent-Puig, Diane Goéré, Jacques R. R. Mathieu, Jerome Cartry, Michel Ducreux, Fanny Jaulin
Publikováno v:
Cancers, Vol 15, Iss 17, p 4418 (2023)
Background: Despite improvements in characterization of CRC heterogeneity, appropriate risk stratification tools are still lacking in clinical practice. This study aimed to elucidate the primary tumor transcriptomic signatures associated with distinc
Externí odkaz:
https://doaj.org/article/faff08ce391f4c46b3b36b41be2f2966
Autor:
Antoine Italiano, Derek Dinart, Isabelle Soubeyran, Carine Bellera, Hélène Espérou, Christelle Delmas, Noémie Mercier, Sabrina Albert, Ludivine Poignie, Anne Boland, Aurélien Bourdon, Damien Geneste, Quentin Cavaille, Yec’han Laizet, Emmanuel Khalifa, Céline Auzanneau, Barbara Squiban, Nathalène Truffaux, Robert Olaso, Zuzana Gerber, Cédrick Wallet, Antoine Bénard, Jean-Yves Blay, Pierre Laurent-Puig, Jean-François Deleuze, Carlo Lucchesi, Simone Mathoulin-Pelissier, the MULTISARC study group
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background Soft-tissue sarcomas (STS) represent a heterogeneous group of rare tumors including more than 70 different histological subtypes. High throughput molecular analysis (next generation sequencing exome [NGS]) is a unique opportunity
Externí odkaz:
https://doaj.org/article/a537e8b223744e2f9d8f9b6743f5ae55
Autor:
Jiayin Deng, Ai-Ling Tian, Hui Pan, Allan Sauvat, Marion Leduc, Peng Liu, Liwei Zhao, Shuai Zhang, Hui Chen, Valérie Taly, Pierre Laurent-Puig, Laura Senovilla, Yingqiu Li, Guido Kroemer, Oliver Kepp
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-11 (2021)
Abstract Colorectal cancers (CRC) can be classified into four consensus molecular subtypes (CMS), among which CMS1 has the best prognosis, contrasting with CMS4 that has the worst outcome. CMS4 CRC is notoriously resistant against therapeutic interve
Externí odkaz:
https://doaj.org/article/db661fab98d84368a6c5b4303d5f4dd5
Autor:
Adrien Grancher, Ludivine Beaussire, Sylvain Manfredi, Karine Le Malicot, Marie Dutherage, Vincent Verdier, Claire Mulot, Olivier Bouché, Jean-Marc Phelip, Charles-Briac Levaché, Philippe Deguiral, Sophie Coutant, David Sefrioui, Jean-François Emile, Pierre Laurent-Puig, Frédéric Bibeau, Pierre Michel, Nasrin Sarafan-Vasseur, Côme Lepage, Frederic Di Fiore
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Circulating tumor DNA (ctDNA) is reported to be promising in localized colorectal cancer (CRC). The present study aimed to retrospectively evaluate the impact of ctDNA in patients with a resected stage II CRC from the PROGIGE 13 trial with available
Externí odkaz:
https://doaj.org/article/41144a49e2c646378fbff7e5463cb372