Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Pierre J. Verroust"'
Autor:
Thaneas Prabakaran, Rikke Nielsen, Jakob V Larsen, Søren S Sørensen, Ulla Feldt-Rasmussen, Moin A Saleem, Claus M Petersen, Pierre J Verroust, Erik I Christensen
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25065 (2011)
Injury to the glomerular podocyte is a key mechanism in human glomerular disease and podocyte repair is an important therapeutic target. In Fabry disease, podocyte injury is caused by the intracellular accumulation of globotriaosylceramide. This stud
Externí odkaz:
https://doaj.org/article/72c788fa86ae499e8a72343f6591f3ce
Autor:
Michel Tauc, Philippe Poujeol, Pierre Ronco, Alain Vandewalle, F. Chatelet, Pierre J. Verroust
Publikováno v:
Journal of Histochemistry and Cytochemistry
Journal of Histochemistry and Cytochemistry, Histochemical Society, 2017, 36 (5), pp.523-532. ⟨10.1177/36.5.2895788⟩
Journal of Histochemistry and Cytochemistry, Histochemical Society, 2017, 36 (5), pp.523-532. ⟨10.1177/36.5.2895788⟩
International audience; By use of immunodepletion studies, we characterized four monoclonal antibodies reactive with rabbit brush-border (BB) as specific for aminopeptidase N (AP), dipeptidylpeptidase IV (DPPIV), neutral endopeptidase (EP), and angio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c7dbd03fa5f9d6435e75007b60d27a0
https://hal.archives-ouvertes.fr/hal-02466078
https://hal.archives-ouvertes.fr/hal-02466078
Autor:
Gerd Holmström, Tina Storm, Rikke Nielsen, Katharina Ericson, Jens Michael Hertz, Carina Frykholm, Lisbeth Tranebjærg, Henrik Birn, Erik Ilsø Christensen, Birgitta Sundelin, Pierre J. Verroust, Tryggve Nevéus
Publikováno v:
Nephrology Dialysis Transplantation; Vol 28
Storm, T, Tranebjærg, L, Frykholm, C, Birn, H, Verroust, P J, Nevéus, T, Sundelin, B, Hertz, J M, Holmström, G, Ericson, K, Christensen, E & Nielsen, R 2013, ' Renal phenotypic investigations of megalin-deficient patients : novel insights into tubular proteinuria and albumin filtration ', Nephrology, Dialysis, Transplantation, vol. 28, no. 3, pp. 585-591 . https://doi.org/10.1093/ndt/gfs462
Storm, T, Tranebjærg, L, Frykholm, C, Birn, H, Verroust, P J, Nevéus, T, Sundelin, B, Hertz, J M, Holmström, G, Ericson, K, Christensen, E I & Nielsen, R 2013, ' 'Renal phenotypic investigations of megalin-deficient patients' : novel insights into tubular proteinuria and albumin filtration ', Nephrology, Dialysis, Transplantation, vol. 28, pp. 585-591 . https://doi.org/10.1093/ndt/gfs462
Storm, T, Tranebjærg, L, Frykholm, C, Birn, H, Verroust, P J, Nevéus, T, Sundelin, B, Hertz, J M, Holmström, G, Ericson, K, Christensen, E & Nielsen, R 2013, ' Renal phenotypic investigations of megalin-deficient patients : novel insights into tubular proteinuria and albumin filtration ', Nephrology, Dialysis, Transplantation, vol. 28, no. 3, pp. 585-591 . https://doi.org/10.1093/ndt/gfs462
Storm, T, Tranebjærg, L, Frykholm, C, Birn, H, Verroust, P J, Nevéus, T, Sundelin, B, Hertz, J M, Holmström, G, Ericson, K, Christensen, E I & Nielsen, R 2013, ' 'Renal phenotypic investigations of megalin-deficient patients' : novel insights into tubular proteinuria and albumin filtration ', Nephrology, Dialysis, Transplantation, vol. 28, pp. 585-591 . https://doi.org/10.1093/ndt/gfs462
BackgroundThe reabsorption of filtered plasma proteins, hormones and vitamins by the renal proximal tubules is vital for body homeostasis. Studies of megalin-deficient mice suggest that the large multi-ligand endocytic receptor megalin plays an essen
Autor:
Pierre J. Verroust, Anthony G.W. Norden, Erik Ilsø Christensen, R. V. Thakker, Maria João Saraiva, Christian Jacobsen, Søren K. Moestrup, Mónica Mendes Sousa, Thomas E. Willnow
The kidney is a major organ for uptake of the thyroid hormone thyroxine (T(4)) and its conversion to the active form, triiodothyronine. In the plasma, one of the T(4) carriers is transthyretin (TTR). In the present study we observed that TTR, the tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::345b9e7b1865b042392f8fed9ff8f72c
https://doi.org/10.1074/jbc.m002886200
https://doi.org/10.1074/jbc.m002886200
Publikováno v:
Christensen, E I & Verroust, P J 2008, ' Interstitial fibrosis: Tubular hypothesis versus glomerular hypothesis ', Kidney International, vol. 74, pp. 1233-1236 .
The pathogenesis of renal interstitial fibrosis leading eventually to renal failure is highly debatable. Whereas the so-called tubular hypothesis, involving an increased tubular uptake of potentially toxic substances that induce a variety of cytokine
Publikováno v:
Pflügers Archiv, 456 (6)
Christensen, E I, Raciti, D, Reggiani, L, Verroust, P J & Brändli, A W 2008, ' Gene expression analysis defines the proximal tubule as the compartment for endocytic receptor-mediated uptake in the Xenopus pronephric kidney ', Pflügers Archiv-European Journal of Physiology, vol. 456, pp. 1163-1176 .
Christensen, E I, Raciti, D, Reggiani, L, Verroust, P J & Brändli, A W 2008, ' Gene expression analysis defines the proximal tubule as the compartment for endocytic receptor-mediated uptake in the Xenopus pronephric kidney ', Pflügers Archiv-European Journal of Physiology, vol. 456, pp. 1163-1176 .
Pflügers Archiv, 456 (6)
ISSN:0031-6768
ISSN:1432-2013
ISSN:0031-6768
ISSN:1432-2013
Autor:
Xavier Rousset, A.-D. Kalopissis, Danièle Pastier, Jeannine Demeurie, Jean Chambaz, Charlotte Cywiner-Golenzer, Christophe Klein, Danielle Château, Sonia Dugué-Pujol, François-Patrick Châtelet, Michèle Chabert, Pierre J. Verroust
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 10, Pp 2151-2161 (2007)
We investigated in vivo catabolism of apolipoprotein A-II (apo A-II), a major determinant of plasma HDL levels. Like apoA-I, murine apoA-II (mapoA-II) and human apoA-II (hapoA-II) were reabsorbed in the first segment of kidney proximal tubules of con
Autor:
Søren K. Moestrup, Renata Kozyraki, Michèle Maurice, Germain Trugnan, Pierre J. Verroust, Gwénaëlle Coudroy, Mette Madsen, Jakub Gburek
Publikováno v:
Journal of the American Society of Nephrology. 16:2330-2337
Cubilin is a peripheral apical membrane receptor for multiple ligands that are taken up in several absorptive epithelia. Recently, amnionless (AMN) was identified to form a functional receptor complex with cubilin. By expression in transfected polari
Autor:
Stéphanie Vinot, Renata Kozyraki, Patrick Linsel-Nitschke, Françoise Illien, Franz Rinninger, Françoise Gofflot, Sophie Louvet-Vallée, Emeline Assémat, Pierre J. Verroust, François Châtelet
Publikováno v:
Biology of Reproduction. 72:1079-1086
Histiotrophic nutrition is essential during the peri-implantation development in rodents, but little is known about receptors involved in protein and lipid endocytosis derived from the endometrium and the uterine glands. Previous studies suggested th
Autor:
Renata Kozyraki, Pierre J. Verroust, Patricia L. Allen, R. Bryan Klassen, Laura Tío, Kimberly Crenshaw, Timothy G. Hammond, Sílvia Atrian
Publikováno v:
American Journal of Physiology-Renal Physiology. 287:F393-F403
Although several heavy metal toxins are delivered to the kidney on the carrier protein metallothionein (MT), uncertainty as to how MT enters proximal tubular cells limits treatment strategies. Prompted by reports that MT-I interferes with renal uptak