Výsledky vyhledávání - "Pierre J. Ferré"

Abstract 2400: K01401-020 is a novel anti-VISTA antibody for cancer treatment: Pharmacodynamic impact on non-human primates and human immune system

Autor: Noureddine Loukili, Isabelle Vandenberghe, Olivier Delfour, Françoise Fraboul, Eric Chetaille, Francisco Cruzalegui, Nathalie Corvaïa, Pierre J. Ferré

Publikováno v: Cancer Research. 79:2400-2400

VISTA (V-domain Ig suppressor of T cell activation), also known as PD-1 homolog (PD-1H), is a transmembrane protein which is highly expressed in myeloid cells such as neutrophils, monocytes, macrophages, and dendritic cells, and at low levels on naiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b01957b90cadb6eee9e7d5714a4b51dd
https://doi.org/10.1158/1538-7445.am2019-2400

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Abstract 503: Prostaglandin E2 produced by tumor cells or by the host tumor microenvironment is not completely abolished by aspirin or celecoxib and limits the ability of the host immune system to control tumor growth

Autor: MyTrang Nguyen, Jérôme Besse, John N. Snouwaert, Leigh A. Jania, Pierre J. Ferré, Beverly H. Koller, Barbara Akla, Pragnya Dontu

Publikováno v: Cancer Research. 79:503-503

Prostaglandins are lipid autacoids derived from arachidonic acid (AA). AA released from the cell membrane is metabolized by the sequential actions of prostaglandin G/H synthase or cyclooxygenase (COX) and respective synthases, such as mPGES-1, which

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::609d36a920af6f5c58681e5b7d589652
https://doi.org/10.1158/1538-7445.am2019-503

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Longitudinal Analysis of Gene Expression in Porcine Skeletal Muscle After Post-Injection Local Injury

Autor: Pierre-Louis Toutain, François Hatey, Pierre J. Ferré, Magali SanCristobal, Agnès Bonnet, Gwenola Tosser-Klopp, Laurence Liaubet, Didier Concordet, Emmanuelle Uro-Coste, Hervé P. Lefebvre

Publikováno v: Pharmaceutical Research
Pharmaceutical Research, American Association of Pharmaceutical Scientists, 2007, 24 (8), pp.1480-9. ⟨10.1007/s11095-007-9266-8⟩
Pharmaceutical Research, 2007, 24 (8), pp.1480-9. ⟨10.1007/s11095-007-9266-8⟩
Pharmaceutical Research / Pharmaceutical Research (Dordrecht)
Pharmaceutical Research / Pharmaceutical Research (Dordrecht), 2007, 24 (8), pp.1480-9. ⟨10.1007/s11095-007-9266-8⟩

International audience; PURPOSE: The purpose of this study is to describe the time course of gene expression in a skeletal muscle local injury induced by an intramuscular (IM) injection, and to compare the dynamics of gene expression with pathologica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6b9ba314b202f22100ab07f58a190e6
https://doi.org/10.1007/s11095-007-9266-8

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Simultaneous and minimally invasive assessment of muscle tolerance and bioavailability of different volumes of an intramuscular formulation in the same animals1

Autor: Pierre-Louis Toutain, J. P. Braun, Hervé P. Lefebvre, Pierre J. Ferré, J. Cazaux, Valérie Laroute

Publikováno v: Journal of Animal Science. 84:1295-1301

Evaluation of skeletal muscle tolerance during development of new drug formulations for i.m. use is most often based on terminal methods performed in the target species after slaughtering. The objective of this study was to evaluate the effect of mus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6cb60251ffb7fd8854fb097d72921b26
https://doi.org/10.2527/2006.8451295x

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Comparison of ultrasonography and pharmacokinetic analysis of creatine kinase release for quantitative assessment of postinjection muscle damage in sheep

Autor: Pierre J. Ferré, Hervé P. Lefebvre, Valérie Laroute, Guillaume Chanoit, Martial Manesse, Didier Concordet, Jean-Pierre Ferré

Publikováno v: American Journal of Veterinary Research. 62:1698-1705

Objectives—To investigate and validate noninvasive methods for the quantitative evaluation of postinjection muscle damage. Animals—5 adult sheep. Procedures—Muscle lesions were induced twice in the lumbar region of the longissimus dorsi muscles

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9caf140207834c5edb860fbcd092c50e
https://doi.org/10.2460/ajvr.2001.62.1698

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Chronic lymphatico-venous bypass: surgical technique and aftercare in a porcine model

Autor: Hervé P. Lefebvre, Pierre J. Ferré, Guillaume Chanoit

Publikováno v: Interactive Cardiovascular and Thoracic Surgery
Interactive Cardiovascular and Thoracic Surgery, Oxford University Press (OUP), 2007, 6 (6), pp.705-707

We describe a chronic model of lymphatico-venous bypass in pigs with emphasis to surgical considerations, major per- and postoperative complications. A catheter (silicone or heparin coated polyurethane) was inserted in the thoracic duct of nine pigs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e885adc5c172908cfd5125a084e12ecb
https://doi.org/10.1510/icvts.2007.157867

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Plasma pharmacokinetics of alfaxalone in dogs after an intravenous bolus of Alfaxan-CD RTU

Autor: Millagahamanda G Ranasinghe, Hervé P. Lefebvre, Qiang Li, Kirby Pasloske, Ted Whittem, Pierre J Ferré

Publikováno v: Veterinary Anaesthesia and Analgesia
Veterinary Anaesthesia and Analgesia, Wiley, 2006, 33 (4), pp.229-236. ⟨10.1111/j.1467-2995.2005.00264.x⟩

Objective To determine the pharmacokinetic parameters of alfaxalone in dogs after the intravenous (IV) administration of clinical and supra-clinical doses of a 2-hydroxypropyl-beta-cyclodextrin (HPCD) alfaxalone formulation (Alfaxan-CD RTU). Experime

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f23ffa3b17749cc2210ef9819297db3f
https://pubmed.ncbi.nlm.nih.gov/16764587

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