Zobrazeno 1 - 10
of 149
pro vyhledávání: '"Pierre J, Talbot"'
Autor:
Jérémie Prévost, Romain Gasser, Guillaume Beaudoin-Bussières, Jonathan Richard, Ralf Duerr, Annemarie Laumaea, Sai Priya Anand, Guillaume Goyette, Mehdi Benlarbi, Shilei Ding, Halima Medjahed, Antoine Lewin, Josée Perreault, Tony Tremblay, Gabrielle Gendron-Lepage, Nicolas Gauthier, Marc Carrier, Diane Marcoux, Alain Piché, Myriam Lavoie, Alexandre Benoit, Vilayvong Loungnarath, Gino Brochu, Elie Haddad, Hannah D. Stacey, Matthew S. Miller, Marc Desforges, Pierre J. Talbot, Graham T. Gould Maule, Marceline Côté, Christian Therrien, Bouchra Serhir, Renée Bazin, Michel Roger, Andrés Finzi
Publikováno v:
Cell Reports Medicine, Vol 1, Iss 7, Pp 100126- (2020)
Summary: SARS-CoV-2 is responsible for the coronavirus disease 2019 (COVID-19) pandemic, infecting millions of people and causing hundreds of thousands of deaths. The Spike glycoproteins of SARS-CoV-2 mediate viral entry and are the main targets for
Externí odkaz:
https://doaj.org/article/f77f34cf5d734e3f9175ba9330620ffe
Autor:
Alan H. M. Wong, Aidan C. A. Tomlinson, Dongxia Zhou, Malathy Satkunarajah, Kevin Chen, Chetna Sharon, Marc Desforges, Pierre J. Talbot, James M. Rini
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Coronaviruses have a relatively high mutation rate, potentially allowing fast adaptation to changing pressures. Here, Wong et al. provide the structure of the receptor-binding domain (RBD) of the human coronavirus HCoV-229E and its receptor and analy
Externí odkaz:
https://doaj.org/article/f6588e45349a4419aa4c7ce1d24b3317
Autor:
Zhijie Li, Aidan CA Tomlinson, Alan HM Wong, Dongxia Zhou, Marc Desforges, Pierre J Talbot, Samir Benlekbir, John L Rubinstein, James M Rini
Publikováno v:
eLife, Vol 8 (2019)
The coronavirus S-protein mediates receptor binding and fusion of the viral and host cell membranes. In HCoV-229E, its receptor binding domain (RBD) shows extensive sequence variation but how S-protein function is maintained is not understood. Report
Externí odkaz:
https://doaj.org/article/eed3c0e9a1a2460c8ad3b9c833f16c92
Autor:
Danielle E. Anderson, Kristin Pfeffermann, So Young Kim, Bevan Sawatsky, James Pearson, Mikhail Kovtun, David L. Corcoran, Yvonne Krebs, Kristmundur Sigmundsson, Sharon F. Jamison, Zhen Zhen Joanna Yeo, Linda J. Rennick, Lin-Fa Wang, Pierre J. Talbot, W. Paul Duprex, Mariano A. Garcia-Blanco, Veronika von Messling
Publikováno v:
mBio, Vol 10, Iss 3 (2019)
ABSTRACT Paramyxoviruses and pneumoviruses have similar life cycles and share the respiratory tract as a point of entry. In comparative genome-scale siRNA screens with wild-type-derived measles, mumps, and respiratory syncytial viruses in A549 cells,
Externí odkaz:
https://doaj.org/article/458b77fa67604a6a92aa29f115dcdb71
Autor:
Pierre J, Talbot, Marc, Desforges
Publikováno v:
Virologie (Montrouge, France). 26(4)
For a large proportion of mankind, the word coronavirus only became a reality in the year 2020, as it was the cause of one of the worst pandemics of the last two centuries. Nevertheless, well before this ominous moment, human coronaviruses (HCoV) wer
Autor:
Alain Le Coupanec, Marc Desforges, Mathieu Meessen-Pinard, Mathieu Dubé, Robert Day, Nabil G Seidah, Pierre J Talbot
Publikováno v:
PLoS Pathogens, Vol 11, Iss 11, p e1005261 (2015)
Human coronaviruses (HCoV) are respiratory pathogens that may be associated with the development of neurological diseases, in view of their neuroinvasive and neurotropic properties. The viral spike (S) glycoprotein is a major virulence factor for sev
Externí odkaz:
https://doaj.org/article/208ee58fe19640f4ad635ae82303b18a
Autor:
Marc Desforges, Jonathan Richard, Antoine Lewin, Annemarie Laumaea, Jérémie Prévost, Elie Haddad, Michel Roger, Alexandre Benoit, Josée Perreault, Pierre J. Talbot, Diane Marcoux, Alain Piché, Christian Therrien, Nicolas Gauthier, Renée Bazin, Graham T. Gould Maule, Tony Tremblay, Romain Gasser, Mehdi Benlarbi, Sai Priya Anand, Matthew S. Miller, Halima Medjahed, Shilei Ding, Gino Brochu, Andrés Finzi, Guillaume Beaudoin-Bussières, Marc Carrier, Vilayvong Loungnarath, Ralf Duerr, Guillaume Goyette, Gabrielle Gendron-Lepage, Hannah D. Stacey, Bouchra Serhir, Marceline Côté, Myriam Lavoie
Publikováno v:
Cell Reports. Medicine
bioRxiv
Cell Reports Medicine
Cell Reports Medicine, Vol 1, Iss 7, Pp 100126-(2020)
bioRxiv
Cell Reports Medicine
Cell Reports Medicine, Vol 1, Iss 7, Pp 100126-(2020)
The SARS-CoV-2 virus is responsible for the coronavirus disease 2019 (COVID-19) pandemic, infecting millions of people and causing hundreds of thousands of deaths. The Spike glycoproteins of SARS-CoV-2 mediates viral entry and is the main target for
Autor:
Élodie Brison, Dominique J. Favreau, Jessica Desjardins, Pierre J. Talbot, Marc Desforges, Hélène Jacomy, Mathieu Meessen-Pinard
Publikováno v:
Neuroviral Infections ISBN: 9780429173868
The viruses that penetrate the central nervous system (CNS) possess neuroinvasive properties and are usually also neurotropic, meaning that they infect neural cells (neurons and glial cells) and by doing so may also become neurovirulent as they can p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1635b13b583af62f8a0a82860269b981
https://doi.org/10.1201/b15082-10
https://doi.org/10.1201/b15082-10
Human respiratory coronaviruses : neuroinvasive, neurotropic and potentially neurovirulent pathogens
Autor:
Marc, Desforges, Alain, Le Coupanec, Élodie, Brison, Mathieu, Meessen-Pinard, Pierre J, Talbot
Publikováno v:
Virologie (Montrouge, France). 18(1)
In humans, viral infections of the respiratory tract are a leading cause of morbidity and mortality worldwide. Among the various respiratory viruses, coronaviruses are important ubiquitous pathogens of humans and animals. Since the late 1960's, human
Autor:
Samir Benlekbir, Pierre J. Talbot, Dongxia Zhou, Aidan C. A. Tomlinson, John L. Rubinstein, Alan H. M. Wong, Zhijie Li, Marc Desforges, James M. Rini
Publikováno v:
eLife
eLife, Vol 8 (2019)
eLife, Vol 8 (2019)
The coronavirus S-protein mediates receptor binding and fusion of the viral and host cell membranes. In HCoV-229E, its receptor binding domain (RBD) shows extensive sequence variation but how S-protein function is maintained is not understood. Report