Zobrazeno 1 - 10
of 184
pro vyhledávání: '"Pierre Garcia"'
Autor:
Muhammad Ali, Pierre Garcia, Laetitia P. Lunkes, Alessia Sciortino, Melanie Thomas, Tony Heurtaux, Kamil Grzyb, Rashi Halder, Djalil Coowar, Alex Skupin, Luc Buée, David Blum, Manuel Buttini, Enrico Glaab
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-19 (2024)
Abstract Alzheimer’s disease (AD) progression and pathology show pronounced sex differences, but the factors driving these remain poorly understood. To gain insights into early AD-associated molecular changes and their sex dependency for tau pathol
Externí odkaz:
https://doaj.org/article/84ce9f86bee048dab648269413092647
Autor:
Kristopher J. Schmit, Pierre Garcia, Alessia Sciortino, Velma T.E. Aho, Beatriz Pardo Rodriguez, Mélanie H. Thomas, Jean-Jacques Gérardy, Irati Bastero Acha, Rashi Halder, Camille Cialini, Tony Heurtaux, Irina Ostahi, Susheel B. Busi, Léa Grandmougin, Tuesday Lowndes, Yogesh Singh, Eric C. Martens, Michel Mittelbronn, Manuel Buttini, Paul Wilmes
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113071- (2023)
Summary: Parkinson’s disease (PD) is a neurological disorder characterized by motor dysfunction, dopaminergic neuron loss, and alpha-synuclein (αSyn) inclusions. Many PD risk factors are known, but those affecting disease progression are not. Life
Externí odkaz:
https://doaj.org/article/c8ff2342a7c34ecfa2de37f394f441e9
Autor:
Yujuan Gui, Kamil Grzyb, Mélanie H. Thomas, Jochen Ohnmacht, Pierre Garcia, Manuel Buttini, Alexander Skupin, Thomas Sauter, Lasse Sinkkonen
Publikováno v:
Epigenetics & Chromatin, Vol 14, Iss 1, Pp 1-20 (2021)
Abstract Background Cell types in ventral midbrain are involved in diseases with variable genetic susceptibility, such as Parkinson’s disease and schizophrenia. Many genetic variants affect regulatory regions and alter gene expression in a cell-typ
Externí odkaz:
https://doaj.org/article/e4649b828cf44d01a3390a57108ae561
Autor:
Luca Mologni, Sébastien Tardy, Alfonso Zambon, Alexandre Orsato, Cédric Schneider, William H. Bisson, Monica Ceccon, Michela Viltadi, David Goyard, Pierre Garcia, Joseph D’Attoma, Sara Pannilunghi, Vito Vece, Jerome Bertho, David Gueyrard, Peter Goekjian, Leonardo Scapozza, Carlo Gambacorti-Passerini
Publikováno v:
ACS Omega, Vol 7, Iss 25, Pp 22059-22060 (2022)
Externí odkaz:
https://doaj.org/article/06412c463a324452867b30b2e8ae1c45
Autor:
Alessia Caputo, Sara Sartini, Elisabetta Levati, Ilaria Minato, Gian Marco Elisi, Adriana Di Stasi, Catherine Guillou, Peter G. Goekjian, Pierre Garcia, David Gueyrard, Stéphane Bach, Arnaud Comte, Simone Ottonello, Silvia Rivara, Barbara Montanini
Publikováno v:
Antibiotics, Vol 11, Iss 10, p 1449 (2022)
Bacterial resistance represents a major health problem worldwide and there is an urgent need to develop first-in-class compounds directed against new therapeutic targets. We previously developed a drug-discovery platform to identify new antimicrobial
Externí odkaz:
https://doaj.org/article/7ef6bd0a1f0244f082ea0dce5fc2f98a
Autor:
Yujuan Gui, Mélanie H. Thomas, Pierre Garcia, Mona Karout, Rashi Halder, Alessandro Michelucci, Heike Kollmus, Cuiqi Zhou, Shlomo Melmed, Klaus Schughart, Rudi Balling, Michel Mittelbronn, Joseph H. Nadeau, Robert W. Williams, Thomas Sauter, Manuel Buttini, Lasse Sinkkonen
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Dopaminergic neurons in the midbrain are of particular interest due to their role in diseases such as Parkinson’s disease and schizophrenia. Genetic variation between individuals can affect the integrity and function of dopaminergic neurons but the
Externí odkaz:
https://doaj.org/article/54d054775e744ce8a53a0661038a6a2d
Autor:
Enrico Glaab, Paul Antony, Sandra Köglsberger, Julia Ilona Forster, Maria Lorena Cordero-Maldonado, Alexander Crawford, Pierre Garcia, Manuel Buttini
Publikováno v:
Data in Brief, Vol 25, Iss , Pp - (2019)
Ubiquitin specific peptidase 9 (USP9) is a deubiquitinase encoded by a sex-linked gene with a Y-chromosomal form (USP9Y) and an X-chromosomal form (USP9X) that escapes X-inactivation. Since USP9 is a key regulatory gene with sex-linked expression in
Externí odkaz:
https://doaj.org/article/0bae04ca43b94de4813b14e9a08d8ccc
Combination of gold catalysis and Selectfluor for the synthesis of fluorinated nitrogen heterocycles
Autor:
Antoine Simonneau, Pierre Garcia, Jean-Philippe Goddard, Virginie Mouriès-Mansuy, Max Malacria, Louis Fensterbank
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 7, Iss 1, Pp 1379-1386 (2011)
We herein report the synthesis of 3-fluoro-2-methylene-pyrrolidine (3a) and -piperidine (3b) from 1,5- and 1,6-aminoalkynes, respectively, using a combination of a gold-catalyzed hydroamination reaction followed by electrophilic trapping of an interm
Externí odkaz:
https://doaj.org/article/179b48695e844b008f57d98b7915dfbb
Autor:
Amélie Quiquerez, Jean-Pierre Garcia, Samuel Dequiedt, Christophe Djemiel, Sébastien Terrat, Olivier Mathieu, Audrey Sassi, Lionel Ranjard
Publikováno v:
OENO One. 56:223-237
Present-day soil physicochemical characteristics, land use/land cover (LULC), and field management practices are commonly recognised as the main drivers shaping archaeal/bacterial and fungal communities in vineyard soils. Few studies have investigate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8aabc79021fb196c74183f2b3f8c20f
https://doi.org/10.20870/oeno-one.2022.56.2.5432
https://doi.org/10.20870/oeno-one.2022.56.2.5432
Publikováno v:
Atlantis Highlights in Engineering ISBN: 9789464631555
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30561ca019ecfc252f5e4411245ec6cf
https://doi.org/10.2991/978-94-6463-156-2_8
https://doi.org/10.2991/978-94-6463-156-2_8
