Zobrazeno 1 - 10 of 40 pro vyhledávání: '"Pierre Fons"'
5
Abstract 4150: Enriching for adenosine antagonist patient responses through deep learning
Autor: Isabella Alt, Robert Shelke, Anna Lobley, Claudia Baumgaertler, Maja Stulic, Pierre Fons, Mark Whittaker, Klaus Hackner, Lucia Dzurillova, Edga Petru, Laudia Hadjari, Judith Lafleur, Josef Singer, Nikolaus Krall, Lukas Hefler, Thorsten Füreder, Christina Taubert, Christophe Boudesco, Andrew Payne, Gregory Ian Vladimer
Publikováno v: Cancer Research. 82:4150-4150
Background: Adenosine signaling is a key metabolic pathway regulating tumor immunity. The conversion of inflammatory extracellular ATP into immunosuppressive adenosine invokes signaling of the A2a receptor (A2AR) in the tumor microenvironment. This d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::46bac76953ae982aed728f8079956858
https://doi.org/10.1158/1538-7445.am2022-4150
Zobrazit plný text záznamu
6
Abstract CT206: EVT801, a novel selective VEGFR-3 inhibitor targeting tumor angiogenesis, started enrollment for its phase I first-in-human study
Autor: Carlos Gomez roca, Philippe Cassier, Marie Mandron, Myriam Estrabaut, Nathalie Delesque-Touchard, Adam C. Smith, Amy Klawitter, Leesa Gentry, Pierre Fons, Michael R. Paillasse, Lise Davenne, Michael Fitzgerald, James Garner, Jean-Pierre Delord
Publikováno v: Cancer Research. 82:CT206-CT206
Introduction: EVT801 is a highly selective, orally available VEGFR3 inhibitor that strongly inhibits angiogenesis without inducing hypoxia, considered one of the main causes of cancer-associated immunosuppression. EVT801 has shown compelling single a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6fae4f0d1e0743ec14cffdced09d61f9
https://doi.org/10.1158/1538-7445.am2022-ct206
Zobrazit plný text záznamu
7
Elektronická kniha
La vie ne m’apprend rien
Autor: Pierre Fons
La vie ne m'apprend rien dévoile le parcours de Vincent, un jeune homme audacieux, à la fois loyal en amour et en amitié. Au fil du temps, il sera confronté aux vicissitudes de la vie, oscillant entre des moments de bonheur intense et les blessur
Zobrazit plný text záznamu
8
Abstract 1731: EXS21546, a non-CNS penetrant A2AR-selective antagonist for anti-cancer immunotherapy
Autor: Emilie Mirey, Florie Bertrand, Andrew Simon Bell, Gregory I. Vladimer, Emilie Pelissier, Isabella Alt, Mark Whittaker, Pierre Fons, Joost van Ham, Stephanie Versluys, Andrew Payne, Michael R. Paillasse, Christina Taubert, Virgile Visentin, Sabrina Pagliarusco
Publikováno v: Cancer Research. 81:1731-1731
Elevated levels of adenosine found in the tumor microenvironment have been highlighted as a potential mechanism contributing to the restricted efficacy of immune checkpoint inhibitors. While the advent of these inhibitors has brought significant bene
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::501fd2b7b9a495ec65303724e2b1da20
https://doi.org/10.1158/1538-7445.am2021-1731
Zobrazit plný text záznamu
9
Tumor Vasculature Is Regulated by FGF/FGFR Signaling-Mediated Angiogenesis and Bone Marrow-Derived Cell Recruitment: This Mechanism Is Inhibited by SSR128129E, the First Allosteric Antagonist of FGFRs
Autor: Françoise Bono, Jean-Marc Herbert, Dol Frédérique, Cécile Volle-Challier, Geneviève Gueguen-Dorbes, Paul J. Schaeffer, Fabien Geronimi, Joël Tuyaret, Jean-Pascal Herault, Pierre Fons
Publikováno v: Journal of Cellular Physiology. 230:43-51
Tumor angiogenesis is accompanied by vasculogenesis, which is involved in the differentiation and mobilization of human bone marrow cells. In order to further characterize the role of vasculogenesis in the tumor growth process, the effects of FGF2 on
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::87531643b63933ed4d9e2a451f0031d6
https://doi.org/10.1002/jcp.24656
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje