Zobrazeno 1 - 10
of 307
pro vyhledávání: '"Pierre Druilhe"'
Autor:
Jean-François Trape, Nafissatou Diagne, Fatoumata Diene-Sarr, Joseph Faye, Fambaye Dieye-Ba, Hubert Bassène, Abdoulaye Badiane, Charles Bouganali, Adama Tall, Ramatoulaye Ndiaye, Souleymane Doucouré, Amélé Nyedzie Wotodjo, Inès Vigan-Womas, Micheline Guillotte-Blisnick, Cheikh Talla, Makhtar Niang, Aissatou Touré-Baldé, Ronald Perraut, Christian Roussilhon, Pierre Druilhe, Christophe Rogier, Odile Mercereau-Puijalon, Cheikh Loucoubar, Cheikh Sokhna
Publikováno v:
EClinicalMedicine, Vol 67, Iss , Pp 102379- (2024)
Summary: Background: Despite significant progress in malaria control over the past twenty years, malaria remains a leading cause of child morbidity and mortality in Tropical Africa. As most patients do not consult any health facility much uncertainty
Externí odkaz:
https://doaj.org/article/aa4cb839dfbc4752a8559a8cf745fb4e
Autor:
Rajeev K. Tyagi, Patrick J. Gleeson, Ludovic Arnold, Rachida Tahar, Eric Prieur, Laurent Decosterd, Jean-Louis Pérignon, Piero Olliaro, Pierre Druilhe
Publikováno v:
BMC Medicine, Vol 16, Iss 1, Pp 1-19 (2018)
Abstract Background Humanity has become largely dependent on artemisinin derivatives for both the treatment and control of malaria, with few alternatives available. A Plasmodium falciparum phenotype with delayed parasite clearance during artemisinin-
Externí odkaz:
https://doaj.org/article/10d1bab21c5c413dbc48428c362b380e
Autor:
Stéphanie Ghosn, Soulaima Chamat, Eric Prieur, Antoine Stephan, Pierre Druilhe, Hasnaa Bouharoun-Tayoun
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The lack of preclinical models able to faithfully predict the immune responses which are later obtained in the clinic is a major hurdle for vaccines development as it increases markedly the delays and the costs required to perform clinical studies. W
Externí odkaz:
https://doaj.org/article/84f760b932b4463aa9e0a48622d4c8dc
Autor:
Janaiara A. Cunha, Leonardo J. M. Carvalho, Cesare Bianco-Junior, Márcia C. R. Andrade, Lilian R. Pratt-Riccio, Evelyn K. P. Riccio, Marcelo Pelajo-Machado, Igor J. da Silva, Pierre Druilhe, Cláudio Tadeu Daniel-Ribeiro
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)
A major constraint in the study of Plasmodium falciparum malaria, including vaccine development, lies on the parasite's strict human host specificity and therefore the shortage of animal experimental models able to harbor human plasmodia. The best ex
Externí odkaz:
https://doaj.org/article/5651495a8f2647f2a3788e004cce131c
Autor:
Masanori Yagi, Gilles Bang, Takahiro Tougan, Nirianne M Q Palacpac, Nobuko Arisue, Taiki Aoshi, Yoshitsugu Matsumoto, Ken J Ishii, Thomas G Egwang, Pierre Druilhe, Toshihiro Horii
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98460 (2014)
The malaria vaccine candidate antigen, SE36, is based on the N-terminal 47 kDa domain of Plasmodium falciparum serine repeat antigen 5 (SERA5). In epidemiological studies, we have previously shown the inhibitory effects of SE36 specific antibodies on
Externí odkaz:
https://doaj.org/article/ca039e53734d4cca984f604e67ef3563
Autor:
Joel G. Breman, Wenceslaus L. Kilama, Brian Greenwood, Pierre Druilhe, David Nabarro, Kamini Mendis
Publikováno v:
Bulletin of the World Health Organization, Vol 78, Iss 12, Pp 1450-1455 (2000)
Externí odkaz:
https://doaj.org/article/0b441577a5234c078a079ab4e5fc7dff
Autor:
Claude Oeuvray, Hasnaa Bouharoun-Tayoun, Heléne Grass-Masse, Jean Paul Iepers, Laurence Ralamboranto, André Tartar, Pierre Druilhe
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 89, Pp 77-80 (1994)
We report the identification of a 48kDa antigen targeted by antibodies which inhibit Plasmodium falciparum in vitro growth by cooperation with blood monocytes in an ADCI assay correlated to the naturally acquired protection. This protein is located o
Externí odkaz:
https://doaj.org/article/2e72a01a40be4969a05194519c1827f7
Autor:
Pierre Daubersies, Selma Sallenave-Sales, Jean Francois Trape, Lucie Raharimalala, Christophe Rogier, Hughes Contamin, Thierry Fandeur, Claudio T. Daniel-Ribeiro, Odile Mercereau-Puijalon, Pierre Druilhe
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 89, Pp 9-12 (1994)
Externí odkaz:
https://doaj.org/article/6c90e3d98b3e4ca6a1a3d2f6116ee91e
Autor:
Ludovic Arnold, Rajeev Kumar Tyagi, Pedro Meija, Claire Swetman, James Gleeson, Jean-Louis Pérignon, Pierre Druilhe
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e18045 (2011)
BACKGROUND: It has been shown previously that it is possible to obtain growth of Plasmodium falciparum in human erythrocytes grafted in mice lacking adaptive immune responses by controlling, to a certain extent, innate defences with liposomes contain
Externí odkaz:
https://doaj.org/article/7a3775e33f7d418a9a582b918995a81b
Autor:
James S McCarthy, Joanne Marjason, Suzanne Elliott, Paul Fahey, Gilles Bang, Elissa Malkin, Eveline Tierney, Hayley Aked-Hurditch, Christopher Adda, Nadia Cross, Jack S Richards, Freya J I Fowkes, Michelle J Boyle, Carole Long, Pierre Druilhe, James G Beeson, Robin F Anders
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24413 (2011)
In a previous Phase 1/2b malaria vaccine trial testing the 3D7 isoform of the malaria vaccine candidate Merozoite surface protein 2 (MSP2), parasite densities in children were reduced by 62%. However, breakthrough parasitemias were disproportionately
Externí odkaz:
https://doaj.org/article/48362a580ee849fd841b7e69abb62ab8