Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Pierre Dodey"'
Autor:
Jean Martinez, Jean-Michel Luccarini, Pierre Dodey, Isabelle Daffix, Jean-Luc Paquet, Muriel Amblard, Philippe Bedos, Didier Pruneau, Christophe Olivier
Publikováno v:
Journal of Medicinal Chemistry. 43:2382-2386
We recently described a potent bradykinin B(2) receptor agonist (JMV1116) obtained by replacing the D-Tic-Oic dipeptide moiety of HOE140 by a (3S)-amino-5-(carbonylmethyl)-2,3-dihydro-1, 5-benzothiazepin-4(5H)-one (D-BT) moiety. This compound inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f48b33620d57e24ae2cbfaa18af8f2d
https://doi.org/10.1021/jm990961s
https://doi.org/10.1021/jm990961s
Autor:
Jean Martinez, Monique Calmes, Didier Pruneau, Isabelle Daffix, Muriel Amblard, Pierre Bélichard, Pierre Dodey, Jean-Luc Paquet, Gilbert Bergé, Jean-Michel Luccarini
Publikováno v:
Journal of Medicinal Chemistry. 42:4193-4201
We have previously shown that substitution of the D-Tic-Oic dipeptide by a (3S)-[amino]-5-(carbonylmethyl)-2,3-dihydro-1, 5-benzothiazepin-4(5H)-one (D-BT) moiety in the bradykinin B(2) receptor antagonist HOE 140 resulted in a full potent and select
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fdb681fd38cee46725c5e66488a959e
https://doi.org/10.1021/jm9901531
https://doi.org/10.1021/jm9901531
Autor:
Jean Martinez, Pierre Bélichard, Jean-Luc Paquet, Pierre Dodey, Didier Pruneau, Gilbert Bergé, Isabelle Daffix, Philippe Bedos, Muriel Amblard, Jean-Michel Luccarini
Publikováno v:
Journal of Medicinal Chemistry. 42:4185-4192
A bradykinin analogue (H-Arg-Pro-Pro-Gly-Phe-Ser-D-BT-Arg-OH, 3) in which the Pro-Phe dipeptide was replaced by the (3S)[amino]-5-(carbonylmethyl)-2,3-dihydro-1, 5-benzothiazepin-4(5H)-one (D-BT) moiety has been synthesized. The same modification was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe1c133b8ba3c3e1b1343a027cbfa637
https://doi.org/10.1021/jm9901529
https://doi.org/10.1021/jm9901529
Autor:
Bruno Loillier, Pierre Bélichard, Chantal Fouchet, Jean Luc Paquet, Jean-Michel Luccarini, Pierre Dodey, Evelyne Defrêne, Claude Robert, Didier Pruneau, Rose-Marie Franck, Béatrice Cremers, Hervé Duclos
Publikováno v:
Immunopharmacology. 43:187-194
LF 16-0687 (1-[[2,4-dichloro-3-[[(2,4-dimethylquinolin-8-yl)oxy] methyl]phenyl]sulfonyl]-N-[3-[[4-(aminoimethyl) phenyl] carbonylamino]propyl]-2(S)-pyrrolidinecarboxamide) has been selected from a large-scale medicinal chemistry program for further d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ee18234ecabe0be5c7556c07fd24f22
https://doi.org/10.1016/s0162-3109(99)00128-9
https://doi.org/10.1016/s0162-3109(99)00128-9
Autor:
Isabelle Daffix, Muriel Amblard, Jean-Michel Luccarini, Pierre Dodey, Pierre Bélichard, Didier Pruneau, Jean-Luc Paquet, Gilbert Bergé, Jean Martinez
Publikováno v:
Peptides Frontiers of Peptide Science ISBN: 9780792351603
Muriel Amblard, Isabelle Daffix, Gilbert Berge, Pierre Dodey, Didier Pruneau, Jean-Luc Paquet, Pierre Belichard, Jean-Michel Luccarini and Jean Martineza Laboratoire des Aminoacides Peptides et Proteines (LAPP), ESA CNRS 5075, Universites de Montpell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3a699b32bf92a65051dc94ee49d6ab3
https://doi.org/10.1007/0-306-46862-x_34
https://doi.org/10.1007/0-306-46862-x_34
Autor:
Jean-Michel Luccarini, Vincent Peyrou, Jean-Luc Paquet, Christine Massardier, Pierre Dodey, Didier Pruneau, Martine Barth, Michel Bondoux
Publikováno v:
Journal of medicinal chemistry. 55(6)
The bradykinin (BK) B1 receptor is an attractive target for the treatment of chronic pain and inflammation. Starting from a dual B1 and B2 antagonist, novel antagonists were designed that display low-nanomolar affinity for human B1 receptor and selec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e33c0b96e6f71a68d4cdb2b517d77ff2
https://pubmed.ncbi.nlm.nih.gov/22369198
https://pubmed.ncbi.nlm.nih.gov/22369198
Autor:
Pierre Dodey, Khan Ou, Robin Jacques, Francois Bellamy, Jean Bernard Chazan, Marc Pascal, Patrick Dutartre
Publikováno v:
ChemInform. 22
A series of (benzoylphenyl)piperidines has been synthesized and evaluated for activity as immunomodulators. Several of these compounds show good activity in primary screening on the basis of the lymphocytes mitogenic response to Con A, PHA, and PWM.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8542267de6f9960b03416582a0eda08a
https://doi.org/10.1002/chin.199145172
https://doi.org/10.1002/chin.199145172
Autor:
Francois Bellamy, Jean Bernard Chazan, Robin Jacques, Patrick Dutartre, Pierre Dodey, Marc Pascal, Khan Ou
Publikováno v:
Journal of Medicinal Chemistry. 34:1545-1552
A series of (benzoylphenyl)piperidines has been synthesized and evaluated for activity as immunomodulators. Several of these compounds show good activity in primary screening on the basis of the lymphocytes mitogenic response to Con A, PHA, and PWM.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9ffd86c4ba0b9198e0634a77cd1f5fc
https://doi.org/10.1021/jm00109a004
https://doi.org/10.1021/jm00109a004
Autor:
Gilles Subra, ‡ Jean-Michel Luccarini, Philippe Bedos, Jean Martinez, Pierre Dodey, Didier Pruneau, ‡ Jean-Luc Paquet, Muriel Amblard, and André Aumelas
Publikováno v:
Journal of medicinal chemistry. 43(12)
We have previously synthesized a potent and selective B(1) bradykinin receptor antagonist, JMV1645 (H-Lys-Arg-Pro-Hyp-Gly-Igl-Ser-D-BT-OH), containing a dipeptide mimetic ((3S)-amino-5-carbonylmethyl-2,3-dihydro-1, 5-benzothiazepin-4(5H)-one (D-BT) m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37e9e46611f92a27daf18d1617605aa8
https://pubmed.ncbi.nlm.nih.gov/10882365
https://pubmed.ncbi.nlm.nih.gov/10882365
Autor:
Pierre Dodey, Bernard Gautheron
Publikováno v:
Journal of Organometallic Chemistry. 94:441-447
The stereochemistry of some α,γ-disubstituted hetero-bridged ferrocenes has been determined and it has been shown that the transformation of tertiary alcohols by AlLiH 4 + AlCl 3 occurs with retention of the functional carbon configuration. The exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b1859bb1c0c2d965facf3a9e8526535
https://doi.org/10.1016/s0022-328x(00)86953-3
https://doi.org/10.1016/s0022-328x(00)86953-3