Výsledky vyhledávání - "Pierre Dellugat"

Akademický článek

Longitudinal Imaging of the Skull Base Synchondroses Demonstrate Prevention of a Premature Ossification After Recifercept Treatment in Mouse Model of Achondroplasia

Autor: Guylene Rignol, Stephanie Garcia, Florence Authier, Kaamula Smith, Lionel Tosello, Raphael Marsault, Pierre Dellugat, Diogo Goncalves, Marlene Brouillard, Jeffrey Stavenhagen, Luca Santarelli, Christian Czech, Elvire Gouze

Publikováno v: JBMR Plus, Vol 6, Iss 2, Pp n/a-n/a (2022)

ABSTRACT Achondroplasia is the most common form of short‐limb dwarfism. In this disorder, endochondral ossification is impaired due to gain‐of‐function mutation in the Fibroblast Growth Factor Receptor 3 (FGFR3) gene. In addition to short limbs

Externí odkaz: https://doaj.org/article/0694d4e1fd514fcb869434c60bf8dea9

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Akademický článek

In vitro and in vivo characterization of Recifercept, a soluble fibroblast growth factor receptor 3, as treatment for achondroplasia.

Autor: Diogo Gonçalves, Guylène Rignol, Pierre Dellugat, Guido Hartmann, Stephanie Sarrazy Garcia, Jeffrey Stavenhagen, Luca Santarelli, Elvire Gouze, Christian Czech

Publikováno v: PLoS ONE, Vol 15, Iss 12, p e0244368 (2020)

Achondroplasia is a rare genetic disorder caused by mutations in the Fibroblast Growth Factor receptor 3 (FGFR3). These mutations lead to aberrant increase of inhibitory signaling in proliferating chondrocytes at the growth plate. Recifercept is a po

Externí odkaz: https://doaj.org/article/3d5d11543bf346a8a9ab34a57ea43d45

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Longitudinal Imaging of the Skull Base Synchondroses Demonstrate Prevention of a Premature Ossification After Recifercept Treatment in Mouse Model of Achondroplasia

Autor: Kaamula Smith, Guylene Rignol, Stephanie Garcia, Elvire Gouze, Raphael Marsault, Lionel Tosello, Christian Czech, Luca Santarelli, Pierre Dellugat, Jeffrey Stavenhagen, Florence Authier, Diogo Goncalves, Marlene Brouillard

Publikováno v: JBMR Plus. 6

Achondroplasia is the most common form of short-limb dwarfism. In this disorder, endochondral ossification is impaired due to gain-of-function mutation in the Fibroblast Growth Factor Receptor 3 (FGFR3) gene. In addition to short limbs, cranial base

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5509e2206265923d90d9fd707c4b6f51
https://doi.org/10.1002/jbm4.10568

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