Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Pierre Daumar"'
Autor:
Dubois, Clémence, Robin, Dufour, Pierre, Daumar, Corinne, Aubel, Claire, Szczepaniak, Christelle, Blavignac, Emmanuelle, Mounetou, Frédérique, Penault-Llorca, Bamdad, Mahchid
Triple-Negative Basal-Like tumors, representing 15 to 20% of breast cancers, are very aggressive and with poor prognosis. Targeted therapies have been developed extensively in preclinical and clinical studies to open the way for new treatment strateg
Externí odkaz:
http://arxiv.org/abs/1712.03259
Autor:
Pierre Daumar, Bernard Vidalinc, Marie Depresle, Frédérique Penault-Llorca, Corinne Aubel, Emmanuelle Mounetou, Mahchid Bamdad, Antoine Goisnard, Clémence Dubois, Jean Gauthier, Manon Roux
Publikováno v:
Cancers, Vol 13, Iss 4050, p 4050 (2021)
Cancers; Volume 13; Issue 16; Pages: 4050
Cancers
Cancers, MDPI, 2021, 13 (16), pp.4050. ⟨10.3390/cancers13164050⟩
Cancers; Volume 13; Issue 16; Pages: 4050
Cancers
Cancers, MDPI, 2021, 13 (16), pp.4050. ⟨10.3390/cancers13164050⟩
P-gp is the most widely studied MDR protein conferring cellular resistance to many standard or targeted therapeutic agents. For this reason, P-gp chemoresistance evaluation, established before or during chemotherapy, can be very relevant in order to
Autor:
Antoine, Goisnard, Pierre, Daumar, Clémence, Dubois, Corinne, Aubel, Manon, Roux, Marie, Depresle, Jean, Gauthier, Bernard, Vidalinc, Frédérique, Penault-Llorca, Emmanuelle, Mounetou, Mahchid, Bamdad
Publikováno v:
Cancers
Simple Summary Tumoral drug resistance is mainly caused by multidrug resistance transporters (MDR), such as the P-gp, which presents high clinical interest. For this reason, the P-gp-mediated drug resistance diagnosis may be very relevant for optimiz
Autor:
Frédérique Penault-Llorca, Clémence Dubois, Marie Depresle, Antoine Goisnard, Bernard Vidalinc, Emmanuelle Mounetou, Mahchid Bamdad, Jean Gauthier, Pierre Daumar, Corinne Aubel
Publikováno v:
Cancers
Cancers, MDPI, 2021, 13 (8), pp.1945. ⟨10.3390/cancers13081945⟩
Volume 13
Issue 8
Cancers, Vol 13, Iss 1945, p 1945 (2021)
Cancers, MDPI, 2021, 13 (8), pp.1945. ⟨10.3390/cancers13081945⟩
Volume 13
Issue 8
Cancers, Vol 13, Iss 1945, p 1945 (2021)
Simple Summary Cancer spheroids are reproducible and relevant multicellular in vitro preclinical models. Thus, their use is required more and more for drug development processes in oncology in order to improve the prediction of anticancer drugs respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d005905fc1d5b418aee9a1f7e8c4a4b5
http://hdl.handle.net/20.500.12278/29318
http://hdl.handle.net/20.500.12278/29318
Autor:
Corinne Aubel, Frédérique Penault-Lorca, F. Magnier, Clémence Dubois, Emmanuelle Mounetou, Mahchid Bamdad, Fanny Martin, Pierre Daumar, Chervin Hassel, Sylvie Guerder
Publikováno v:
Journal of Clinical Medicine, Vol 9, Iss 1, p 64 (2019)
Journal of Clinical Medicine
Journal of Clinical Medicine, MDPI, 2019, 9 (1), pp.64. ⟨10.3390/jcm9010064⟩
Journal of Clinical Medicine, 2019, 9 (1), pp.64. ⟨10.3390/jcm9010064⟩
Volume 9
Issue 1
Journal of Clinical Medicine
Journal of Clinical Medicine, MDPI, 2019, 9 (1), pp.64. ⟨10.3390/jcm9010064⟩
Journal of Clinical Medicine, 2019, 9 (1), pp.64. ⟨10.3390/jcm9010064⟩
Volume 9
Issue 1
The Triple-Negative Breast Cancer subtype (TNBC) is particularly aggressive and heterogeneous. Thus, Poly-ADP-Ribose Polymerase inhibitors were developed to improve the prognosis of patients and treatment protocols are still being evaluated. In this
Autor:
Christophe Massard, Pierre Daumar, Mahchid Bamdad, Emmanuelle Mounetou, Oscar Komla Awitor, Yves Sibaud, Vincent Raspal, Clémence Dubois
Publikováno v:
Journal of Biomaterials and Nanobiotechnology
Journal of Biomaterials and Nanobiotechnology, Scientific Research, 2018, 09 (01), pp.13-25. ⟨10.4236/jbnb.2018.91002⟩
Journal of Biomaterials and Nanobiotechnology, 2018, 09 (01), pp.13-25. ⟨10.4236/jbnb.2018.91002⟩
Journal of Biomaterials and Nanobiotechnology, Scientific Research, 2018, 09 (01), pp.13-25. ⟨10.4236/jbnb.2018.91002⟩
Journal of Biomaterials and Nanobiotechnology, 2018, 09 (01), pp.13-25. ⟨10.4236/jbnb.2018.91002⟩
International audience; The Triple Negative " Basal-like " breast cancer (TNBL) tumours have a high proliferative capacity and develop a resistance phenotype associated with me-tastases. However, the management of TNBL carcinomas is still not standar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65fdb3a70e63b13dd6b3ea1b9640782a
https://hal.archives-ouvertes.fr/hal-01829452/file/JBNB_2017121515530030.pdf
https://hal.archives-ouvertes.fr/hal-01829452/file/JBNB_2017121515530030.pdf
Autor:
Robin Dufour, Emmanuelle Mounetou, Mahchid Bamdad, Pierre Daumar, Clémence Dubois, Frédérique Penault-Llorca
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis
Journal of Pharmaceutical and Biomedical Analysis, Elsevier, 2018, 152, pp.74-80. ⟨10.1016/j.jpba.2018.01.036⟩
Journal of Pharmaceutical and Biomedical Analysis, Elsevier, 2018, 152, pp.74-80. ⟨10.1016/j.jpba.2018.01.036⟩
International audience; Olaparib is a potent PARP inhibitor in clinical use for cancer therapy. A bioanalytical assay was developed and validated for quantitation of intracellular level of olaparib in cells exposed to the drug. The assay involves an
Autor:
Pierre Daumar, Jean Gauthier, Clémence Dubois, Bernard Vidalinc, Frédérique Penault-Llorca, Mahchid Bamdad, Corinne Aubel, Emmanuelle Mounetou
Publikováno v:
Journal of Clinical Medicine; Volume 8; Issue 3; Pages: 397
Journal of Clinical Medicine Research
Journal of Clinical Medicine Research, Elmer Press, 2019, 8 (3), pp.397. ⟨10.3390/jcm8030397⟩
Journal of Clinical Medicine, Vol 8, Iss 3, p 397 (2019)
Journal of Clinical Medicine
Journal of Clinical Medicine Research
Journal of Clinical Medicine Research, Elmer Press, 2019, 8 (3), pp.397. ⟨10.3390/jcm8030397⟩
Journal of Clinical Medicine, Vol 8, Iss 3, p 397 (2019)
Journal of Clinical Medicine
Triple-negative breast cancers are particularly aggressive. In vitro cultures are one of the major pathways for developing anticancer strategies. The effectiveness and reproducibility of the drug screenings depend largely on the homogeneity of cultur
Autor:
Nagavarakishore Pillarsetty, Vadim Divilov, Nicholas Ramos, Jason S. Lewis, Brian M. Zeglis, Pierre Daumar, Kuntal K. Sevak
Publikováno v:
European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2014, 86, pp.769-781. ⟨10.1016/j.ejmech.2014.09.019⟩
European Journal of Medicinal Chemistry, Elsevier, 2014, 86, pp.769-781. ⟨10.1016/j.ejmech.2014.09.019⟩
Type II topoisomerase (Topo-II) is an ATP-dependent enzyme that is essential in the transcription, replication, and chromosome segregation processes and, as such, represents an attractive target for cancer therapy. Numerous studies indicate that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4402b04154e212dd1b866b3169a1e2a
https://hal.archives-ouvertes.fr/hal-03121843
https://hal.archives-ouvertes.fr/hal-03121843
Autor:
Sean Carlin, Cindy A. Wanger-Baumann, Laura Fabrizio, Jason S. Lewis, Pierre Daumar, Oleg A. Andreev, Nagavarakishore Pillarsetty, Yana K. Reshetnyak
Publikováno v:
Bioconjugate Chemistry
Bioconjugate Chemistry, American Chemical Society, In press, 23 (8), pp.1557-1566. ⟨10.1021/bc3000222⟩
Bioconjugate Chemistry, American Chemical Society, In press, 23 (8), pp.1557-1566. ⟨10.1021/bc3000222⟩
Solid tumors often develop an acidic microenvironment, which plays a critical role in tumor progression and is associated with increased level of invasion and metastasis. The 37-residue pH (low) insertion peptide (pHLIP) is under study as an imaging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cc7deded336b349eefd20679cf28ecb
https://hal.archives-ouvertes.fr/hal-03121688
https://hal.archives-ouvertes.fr/hal-03121688