Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Pierre Danhier"'
Autor:
Santosh Kumar Bharti, Samata Kakkad, Pierre Danhier, Flonne Wildes, Marie-France Penet, Balaji Krishnamachary, Zaver M. Bhujwalla
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 2, Pp 239-246 (2019)
Metastatic dissemination continues to be a major cause of prostate cancer (PCa) mortality, creating a compelling need to understand factors that play a role in the metastatic cascade. Since hypoxia plays an important role in PCa aggressiveness, we ch
Externí odkaz:
https://doaj.org/article/805fae394954438d926c4b84f4035c50
Autor:
Donatienne d’Hose, Pierre Danhier, Heidi Northschield, Pauline Isenborghs, Bénédicte F. Jordan, Bernard Gallez
Publikováno v:
Redox Biology, Vol 40, Iss , Pp 101852- (2021)
In this paper, we describe an assay to analyze simultaneously the oxygen consumption rate (OCR) and superoxide production in a biological system. The analytical set-up uses electron paramagnetic resonance (EPR) spectroscopy with two different isotopi
Externí odkaz:
https://doaj.org/article/19e23b0d3986483b815c1617a5107c3a
Autor:
Debora Grasso, Hyllana C. D. Medeiros, Luca X. Zampieri, Vanesa Bol, Pierre Danhier, Marike W. van Gisbergen, Caroline Bouzin, Davide Brusa, Vincent Grégoire, Hubert Smeets, Alphons P. M. Stassen, Ludwig J. Dubois, Philippe Lambin, Marie Dutreix, Pierre Sonveaux
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
The clinical management of head and neck squamous cell carcinoma (HNSCC) commonly involves chemoradiotherapy, but recurrences often occur that are associated with radioresistance. Using human SQD9 laryngeal squamous cell carcinoma cancer cells as a m
Externí odkaz:
https://doaj.org/article/b78719403dbc49b78722d46c6693f7ee
Autor:
Pierre Danhier, Balaji Krishnamachary, Santosh Bharti, Samata Kakkad, Yelena Mironchik, Zaver M. Bhujwalla
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 17, Iss 12, Pp 871-881 (2015)
Here we have developed a hypoxia response element driven imaging strategy that combined the hypoxia-driven expression of two optical reporters with different half-lives to detect temporal changes in hypoxia and hypoxia inducible factor (HIF) activity
Externí odkaz:
https://doaj.org/article/8417b7cdf0214f999eebec69ceef09d3
(+)-Catechin in a 1:2 Complex with Lysine Inhibits Cancer Cell Migration and Metastatic Take in Mice
Autor:
Valéry L. Payen, Paolo E. Porporato, Pierre Danhier, Thibaut Vazeille, Marine C. N. M. Blackman, Bronislav H. May, Paul Niebes, Pierre Sonveaux
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Metastasis is of dismal prognosis for cancer patients, but recent evidence in mouse models of cancer shows that metastasis prevention is a reachable clinical objective. These experiments indicate that altered mitochondrial activities are associated w
Externí odkaz:
https://doaj.org/article/95937ccc660d4c6ea0b21d3801978ffd
Autor:
Paolo E. Porporato, Valéry L. Payen, Jhudit Pérez-Escuredo, Christophe J. De Saedeleer, Pierre Danhier, Tamara Copetti, Suveera Dhup, Morgane Tardy, Thibaut Vazeille, Caroline Bouzin, Olivier Feron, Carine Michiels, Bernard Gallez, Pierre Sonveaux
Publikováno v:
Cell Reports, Vol 8, Iss 3, Pp 754-766 (2014)
Metastatic progression of cancer is associated with poor outcome, and here we examine metabolic changes underlying this process. Although aerobic glycolysis is known to promote metastasis, we have now identified a different switch primarily affecting
Externí odkaz:
https://doaj.org/article/6374a044c672496fbe49b5ef7133ff74
Autor:
Pierre Danhier, Tamara Copetti, Géraldine De Preter, Philippe Leveque, Olivier Feron, Bénédicte F Jordan, Pierre Sonveaux, Bernard Gallez
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53324 (2013)
Cell detachment is a procedure routinely performed in cell culture and a necessary step in many biochemical assays including the determination of oxygen consumption rates (OCR) in vitro. In vivo, cell detachment has been shown to exert profound metab
Externí odkaz:
https://doaj.org/article/de90c93784ee4ddb884b74521f260193
Autor:
Fabienne Danhier, Pierre Danhier, Nicolas Magotteaux, Géraldine De Preter, Bernard Ucakar, Oussama Karroum, Bénédicte Jordan, Bernard Gallez, Véronique Préat
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40772 (2012)
BACKGROUND: Paclitaxel (PTX) is a potent anti-cancer chemotherapeutic agent and is widely used in the treatments of solid tumors, particularly of the breast and ovaries. An effective and safe micellar formulation of PTX was used to administer higher
Externí odkaz:
https://doaj.org/article/6c2fc95f033647f5968e4dac4dc873e4
Autor:
Pierre Sonveaux, Tamara Copetti, Christophe J De Saedeleer, Frédérique Végran, Julien Verrax, Kelly M Kennedy, Eui Jung Moon, Suveera Dhup, Pierre Danhier, Françoise Frérart, Bernard Gallez, Anthony Ribeiro, Carine Michiels, Mark W Dewhirst, Olivier Feron
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33418 (2012)
Switching to a glycolytic metabolism is a rapid adaptation of tumor cells to hypoxia. Although this metabolic conversion may primarily represent a rescue pathway to meet the bioenergetic and biosynthetic demands of proliferating tumor cells, it also
Externí odkaz:
https://doaj.org/article/4c4c8f177f2d44039c9a0eefa84476cb
Autor:
Bernard Gallez, Pierre Sonveaux, Bénédicte F. Jordan, Vincent Grégoire, Thanh Trang Cao Pham, Lucie Brisson, Pierre Danhier, Caroline Deriemaeker, Géraldine De Preter
Viability of MDA-MB-231 was measured in vitro using trypan blue exclusion after BrdU incorporation measurements. Cancer cells were treated with 50 µM NaHS or vehicle (NaCl 0.9 %) in the presence of pHe = 6.5. No significant cell death was found in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a91917828cbfdd5aba8c864a98a6706f
https://doi.org/10.1158/1535-7163.22503717
https://doi.org/10.1158/1535-7163.22503717