Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Pierre Cunin"'
Autor:
Zhengping Huang, Xiaomeng You, Liang Chen, Yan Du, Kailey Brodeur, Hyuk Jee, Qiang Wang, Grace Linder, Roxane Darbousset, Pierre Cunin, Margaret H. Chang, Alexandra Wactor, Brian M. Wauford, Marc J. C. Todd, Kevin Wei, Ying Li, Anais Levescot, Yoichiro Iwakura, Virginia Pascual, Nicole E. Baldwin, Pierre Quartier, Tianwang Li, Maria T. Gianatasio, Robert P. Hasserjian, Lauren A. Henderson, David B. Sykes, Elizabeth D. Mellins, Scott W. Canna, Julia F. Charles, Peter A. Nigrovic, Pui Y. Lee
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Still’s disease is an inflammatory syndrome linked to the development of further immune dysregulation and hypercytokinaemia termed macrophage activation syndrome. Here the authors implicate the mechanistic target of rapamycin complex 1 in murine mo
Externí odkaz:
https://doaj.org/article/0b6c3e1af33b4a6dbc1260fdb044deab
Autor:
Bianca A. Trombetta, Savannah E. Kandigian, Robert R. Kitchen, Korneel Grauwet, Pia Kivisäkk Webb, Glenn A. Miller, Charles G. Jennings, Sejal Jain, Samara Miller, Yikai Kuo, Thadryan Sweeney, Tal Gilboa, Maia Norman, Daimon P. Simmons, Christopher E. Ramirez, Melissa Bedard, Catherine Fink, Jina Ko, Esmarline J. De León Peralta, Gerald Watts, Emma Gomez-Rivas, Vannessa Davis, Rocky M. Barilla, Jianing Wang, Pierre Cunin, Samuel Bates, Chevaun Morrison-Smith, Benjamin Nicholson, Edmond Wong, Leena El-Mufti, Michael Kann, Anna Bolling, Brooke Fortin, Hayden Ventresca, Wen Zhou, Santiago Pardo, Megan Kwock, Aditi Hazra, Leo Cheng, Q. Rushdy Ahmad, James A. Toombs, Rebecca Larson, Haley Pleskow, Nell Meosky Luo, Christina Samaha, Unnati M. Pandya, Pushpamali De Silva, Sally Zhou, Zakary Ganhadeiro, Sara Yohannes, Rakeisha Gay, Jacqueline Slavik, Shibani S. Mukerji, Petr Jarolim, David R. Walt, Becky C. Carlyle, Lauren L. Ritterhouse, Sara Suliman
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-14 (2021)
Abstract Background COVID-19 has resulted in significant morbidity and mortality worldwide. Lateral flow assays can detect anti-Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) antibodies to monitor transmission. However, standardized eva
Externí odkaz:
https://doaj.org/article/019aff5557364e74bdca28b0b1adff41
Autor:
Ricardo Grieshaber-Bouyer, Felix A. Radtke, Pierre Cunin, Giuseppina Stifano, Anaïs Levescot, Brinda Vijaykumar, Nathan Nelson-Maney, Rachel B. Blaustein, Paul A. Monach, Peter A. Nigrovic, ImmGen Consortium
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-21 (2021)
Differentiating neutrophil functional states is difficult. Here the authors show, using single cell RNA-sequencing and trajectory analyses, that mouse neutrophils can be presented as a transcriptome continuum rather than discrete subsets, but are aff
Externí odkaz:
https://doaj.org/article/a869daba818542d3a779eb3e37bafc52
Autor:
Pierre Cunin, Peter A. Nigrovic
Publikováno v:
Platelets, Vol 31, Iss 6, Pp 700-706 (2020)
Histology of bone marrow routinely identifies megakaryocytes that enclose neutrophils and other hematopoietic cells, a phenomenon termed emperipolesis. Preserved across mammalian species and enhanced with systemic inflammation and platelet demand, th
Externí odkaz:
https://doaj.org/article/93dede694f4f4dbe921ebd6685f84445
Autor:
Bianca A. Trombetta, Savannah E. Kandigian, Robert R. Kitchen, Korneel Grauwet, Pia Kivisäkk Webb, Glenn A. Miller, Charles G. Jennings, Sejal Jain, Samara Miller, Yikai Kuo, Thadryan Sweeney, Tal Gilboa, Maia Norman, Daimon P. Simmons, Christopher E. Ramirez, Melissa Bedard, Catherine Fink, Jina Ko, Esmarline J. De León Peralta, Gerald Watts, Emma Gomez-Rivas, Vannessa Davis, Rocky M. Barilla, Jianing Wang, Pierre Cunin, Samuel Bates, Chevaun Morrison-Smith, Benjamin Nicholson, Edmond Wong, Leena El-Mufti, Michael Kann, Anna Bolling, Brooke Fortin, Hayden Ventresca, Wen Zhou, Santiago Pardo, Megan Kwock, Aditi Hazra, Leo Cheng, Q. Rushdy Ahmad, James A. Toombs, Rebecca Larson, Haley Pleskow, Nell Meosky Luo, Christina Samaha, Unnati M. Pandya, Pushpamali De Silva, Sally Zhou, Zakary Ganhadeiro, Sara Yohannes, Rakiesha Gay, Jacqueline Slavik, Shibani S. Mukerji, Petr Jarolim, David R. Walt, Becky C. Carlyle, Lauren L. Ritterhouse, Sara Suliman
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-2 (2021)
Externí odkaz:
https://doaj.org/article/9bc96019ccbf40a28e5cc85682a0a561
Autor:
Pierre Cunin, Rim Bouslama, Kellie R Machlus, Marta Martínez-Bonet, Pui Y Lee, Alexandra Wactor, Nathan Nelson-Maney, Allyn Morris, Li Guo, Andrew Weyrich, Martha Sola-Visner, Eric Boilard, Joseph E Italiano, Peter A Nigrovic
Publikováno v:
eLife, Vol 8 (2019)
Bone marrow megakaryocytes engulf neutrophils in a phenomenon termed emperipolesis. We show here that emperipolesis is a dynamic process mediated actively by both lineages, in part through the β2-integrin/ICAM-1/ezrin pathway. Tethered neutrophils e
Externí odkaz:
https://doaj.org/article/4657b7ef445d4bc38f95924b75d6f69e
Autor:
Gang Li, Pierre Cunin, Di Wu, Dorothée Diogo, Yu Yang, Yukinori Okada, Robert M Plenge, Peter A Nigrovic
Publikováno v:
PLoS Genetics, Vol 12, Iss 9, p e1006292 (2016)
Understanding the implications of genome-wide association studies (GWAS) for disease biology requires both identification of causal variants and definition of how these variants alter gene function. The non-coding triallelic dinucleotide polymorphism
Externí odkaz:
https://doaj.org/article/ee0b89fcf67541abbb35cd0c8706354f
Autor:
Anthony L Dellinger, Pierre Cunin, David Lee, Andrew L Kung, D Bradford Brooks, Zhiguo Zhou, Peter A Nigrovic, Christopher L Kepley
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0126290 (2015)
Inflammatory arthritis (e.g. rheumatoid arthritis; RA) is a complex disease driven by the interplay of multiple cellular lineages. Fullerene derivatives have previously been shown to have anti-inflammatory capabilities mediated, in part, by their abi
Externí odkaz:
https://doaj.org/article/55ac7fd0382648c197a9154379a4d622
Autor:
James A. Toombs, David R. Walt, Yikai Kuo, Glenn A Miller, Unnati M. Pandya, Christina Samaha, Christopher E. Ramirez, Santiago Pardo, Esmarline J. De Leon Peralta, Gerald F. Watts, Rocky Barilla, Robert R. Kitchen, Brooke Fortin, Daimon P. Simmons, Rebecca C. Larson, Anna Bolling, Vannessa M. Davis, Samuel Bates, Rushdy Ahmad, Jina Ko, Melissa Bedard, Tal Gilboa, Hayden Ventresca, Becky C. Carlyle, Benjamin Nicholson, Pierre Cunin, Sally Zhou, Bianca A. Trombetta, Edmond Wong, Sara Yohannes, Aditi Hazra, Shibani S. Mukerji, Petr Jarolim, Chevaun Morrison-Smith, Charles Jennings, Samara Maxine Miller, Haley M. Pleskow, Pushpamali De Silva, Emma Gomez-Rivas, Michael Kann, Thadryan Sweeney, Wen Zhou, Catherine Fink, Pia Kivisakk Webb, Megan Kwock, Nell Meosky Luo, Leo L. Cheng, Sejal Jain, Maia Norman, Jacqueline M. Slavik, Lauren L. Ritterhouse, Zakary Ganhadeiro, Leena El-Mufti, Jianing Wang, Savannah E. Kandigian, Korneel Grauwet, Sara Suliman
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-14 (2021)
BMC Infectious Diseases
BMC Infectious Diseases
Background COVID-19 has resulted in significant morbidity and mortality worldwide. Lateral flow assays can detect anti-Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) antibodies to monitor transmission. However, standardized evaluation o
Autor:
Mridul Agrawal, Abhishek Niroula, Pierre Cunin, Marie McConkey, Veronica Shkolnik, Peter G. Kim, Waihay J. Wong, Lachelle D. Weeks, Amy E. Lin, Peter G. Miller, Christopher J. Gibson, Aswin Sekar, Inga-Marie Schaefer, Donna Neuberg, Richard M. Stone, Alexander G. Bick, Md Mesbah Uddin, Gabriel K. Griffin, Siddhartha Jaiswal, Pradeep Natarajan, Peter A. Nigrovic, Deepak A. Rao, Benjamin L. Ebert
Publikováno v:
Blood. 140(10)
Gout is a common inflammatory arthritis caused by precipitation of monosodium urate (MSU) crystals in individuals with hyperuricemia. Acute flares are accompanied by secretion of proinflammatory cytokines, including interleukin-1β (IL-1β). Clonal h