Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Pierre Colas"'
Autor:
Pierre Colas
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 15, Iss 1, Pp 1-14 (2020)
Abstract Extensive studies in the past 30 years have established that cyclin-dependent kinases (CDKs) exert many diverse, important functions in a number of molecular and cellular processes that are at play during development. Not surprisingly, mutat
Externí odkaz:
https://doaj.org/article/de154202240d42908abbe8b4b447c5fd
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 9, Iss 10, Pp n/a-n/a (2021)
Abstract Background CDK10 is a poorly known cyclin M (CycM)‐dependent kinase. Loss‐of‐function mutations in the genes encoding CycM or CDK10 cause, respectively, STAR or Al Kaissi syndromes, which present a constellation of malformations and dy
Externí odkaz:
https://doaj.org/article/a9b71a335ec247d798d8c68cdf527e63
Autor:
Thomas Robert, Jared L. Johnson, Roxane Guichaoua, Tomer M. Yaron, Stéphane Bach, Lewis C. Cantley, Pierre Colas
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
Cyclin-dependent kinases (CDKs) constitute a family of 20 serine/threonine protein kinases that play pivotal roles in the regulation of numerous important molecular and cellular processes. CDKs have long been considered promising therapeutic targets
Externí odkaz:
https://doaj.org/article/035492ef7e2b4e65b050f4fe659638a0
Autor:
Thi-Ngoc-Dung Nguyen, Omid Feizbakhsh, Estelle Sfecci, Blandine Baratte, Claire Delehouzé, Adrien Garcia, Corentin Moulin, Pierre Colas, Sandrine Ruchaud, Mohamed Mehiri, Stéphane Bach
Publikováno v:
Marine Drugs, Vol 17, Iss 10, p 569 (2019)
Regulated cell death (RCD) results from the activation of one or more signal transduction modules both in physiological or pathological conditions. It is now established that RCD is involved in numerous human diseases, including cancer. As regulated
Externí odkaz:
https://doaj.org/article/efe9d9089528481dabd378f52d0fc097
Autor:
Perayot Pamonsinlapatham, Réda Hadj-Slimane, Françoise Raynaud, Marc Bickle, Claudine Corneloup, Audrey Barthelaix, Yves Lepelletier, Perrine Mercier, Matthieu Schapira, Jérôme Samson, Anne-Laure Mathieu, Nicolas Hugo, Olivier Moncorgé, Ivan Mikaelian, Sylvie Dufour, Christiane Garbay, Pierre Colas
Publikováno v:
PLoS ONE, Vol 3, Iss 8, p e2902 (2008)
The Ras GTPase-activating protein RasGAP catalyzes the conversion of active GTP-bound Ras into inactive GDP-bound Ras. However, RasGAP also acts as a positive effector of Ras and exerts an anti-apoptotic activity that is independent of its GAP functi
Externí odkaz:
https://doaj.org/article/e97a2dabf7aa4f3a9ac24b82b69a64bb
Autor:
Carmen Garrido, Guido Kroemer, Pierre Colas, Laurent Lagrost, Olivier Micheau, Oleg Deminov, Eric Fourmaux, David Lanneau, Arlette Hammann, Jean Paul Pais de Barros, Elise Schmitt, Aurelie De Thonel, Jessica Gobbo, Anne-Laure Rérole
Supplementary Figures 1-7, Table 1 from Peptides and Aptamers Targeting HSP70: A Novel Approach for Anticancer Chemotherapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a69b677b63a40ff86da50e618112d6e
https://doi.org/10.1158/0008-5472.22387271
https://doi.org/10.1158/0008-5472.22387271
Publikováno v:
Molecular Genetics & Genomic Medicine
Molecular Genetics & Genomic Medicine, Wiley Periodicals, Inc. In press, ⟨10.1002/mgg3.1782⟩
Molecular Genetics & Genomic Medicine, Vol 9, Iss 10, Pp n/a-n/a (2021)
Molecular Genetics & Genomic Medicine, Wiley Periodicals, Inc. In press, ⟨10.1002/mgg3.1782⟩
Molecular Genetics & Genomic Medicine, Vol 9, Iss 10, Pp n/a-n/a (2021)
Background CDK10 is a poorly known cyclin M (CycM)‐dependent kinase. Loss‐of‐function mutations in the genes encoding CycM or CDK10 cause, respectively, STAR or Al Kaissi syndromes, which present a constellation of malformations and dysfunction
Autor:
Mouad Alami, Jean-Daniel Brion, Pascal Bonnet, Abdallah Hamze, Nada Ibrahim, Pierre Colas, Jean-François Peyrat, Thomas Robert, Samir Messaoudi, Jérôme Bignon, Stéphane Bach, Béatrice Josselin, Hélène Levaique
Publikováno v:
European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2020, 199 (31), pp.112355. ⟨10.1016/j.ejmech.2020.112355⟩
European Journal of Medicinal Chemistry, 2020, 199 (31), pp.112355. ⟨10.1016/j.ejmech.2020.112355⟩
European Journal of Medicinal Chemistry, Elsevier, 2020, 199 (31), pp.112355. ⟨10.1016/j.ejmech.2020.112355⟩
European Journal of Medicinal Chemistry, 2020, 199 (31), pp.112355. ⟨10.1016/j.ejmech.2020.112355⟩
International audience; In this work, unique structure of flavopiridol analogs bearing thiosugars, amino acids and heterocyclic moieties tethered to the flavopiridol via thioether and amine bonds mainly on its C ring have been prepared. The analogs b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fd8e4f320b04c9aaeb01d1f5e7b01da
https://hal.archives-ouvertes.fr/hal-03036489
https://hal.archives-ouvertes.fr/hal-03036489
Publikováno v:
Medecine sciences : M/S. 36(5)
Yeast has been used for thousands of years as a leavening agent and for alcoholic fermentation, but it is only in 1857 that Louis Pasteur described the microorganism at the basis of these two tremendously important economic activities. From there, ye