Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Pierre Chardin"'
Autor:
Hélène, Barelli, Jacques, Camonis, Jean, de Gunzburg, Bruno, Goud, Françoise, Moreau-Gachelin, Alfred, Wittinghofer, Pierre, Chardin
Publikováno v:
Medecine sciences : M/S. 36(4)
Autor:
Emmanuel Lemichez, Laurent Boyer, Gérard Gacon, Patrick Lorès, Pierre Chardin, Orane Visvikis
Publikováno v:
FEBS Journal. 275:386-396
UNLABELLED Ubiquitination and proteasomal degradation have recently emerged as an additional level of regulation of activated forms of Rho GTPases. To characterize this novel regulatory pathway and to gain insight into its biological significance, we
Publikováno v:
FEBS Journal. 274:5518-5532
The small G protein Rap1 regulates diverse cellular processes such as integrin activation, cell adhesion, cell-cell junction formation and cell polarity. It is crucial to identify Rap1 effectors to better understand the signalling pathways controllin
Autor:
Pierre Chardin
Publikováno v:
Nature Reviews Molecular Cell Biology. 7:54-62
The Rnd proteins, which form a distinct sub-group of the Rho family of small GTP-binding proteins, have been shown to regulate the organization of the actin cytoskeleton in several tissues. In the brain, they participate in neurite extension, whereas
Autor:
M Finet, Vincent Sauzeau, Nathalie Vaillant, Pierre Chardin, Pierre Pacaud, F. Heutte, Gervaise Loirand, G Reillaudoux, Chrystelle Cario-Toumaniantz
Publikováno v:
The Journal of Physiology. 552:403-413
During pregnancy, the uterus undergoes major functional and structural remodelling. It is well known that during the major part of pregnancy, the myometrium normally remains relatively quiescent but is able to generate powerful contractions at the ti
Autor:
Mirjam M. P. Zegers, Pierre Chardin, Pablo Rodriguez-Viciana, Steen H. Hansen, Keith E. Mostov, Martin McMahon, Melissa A. Woodrow
Publikováno v:
Molecular and Cellular Biology. 20:9364-9375
Madin-Darby canine kidney (MDCK) epithelial cells transformed by oncogenic Ras and Raf exhibit cell multilayering and alterations in the actin cytoskeleton. The changes in the actin cytoskeleton comprise a loss of actin stress fibers and enhanced cor
Autor:
Alain-Pierre Gadeau, Nathalie Vaillant, Chrystelle Cario-Toumaniantz, Claude Desgranges, Pierre Chardin, Elizabeth Scalbert, Hélène Le Jeune, Gervaise Loirand, Vincent Sauzeau, Pierre Pacaud
Publikováno v:
Europe PubMed Central
In the cardiovascular system, activation of ionotropic (P2X receptors) and metabotropic (P2Y receptors) P2 nucleotide receptors exerts potent and various responses including vasodilation, vasoconstriction, and vascular smooth muscle cell proliferatio
Autor:
Jacqueline Cherfils, Pierre Chardin
Publikováno v:
Trends in Biochemical Sciences. 24:306-311
Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. Guanine-nucleotide-exchange factors (GEFs) positively regulate th
Publikováno v:
The Journal of Physiology. 516:825-834
1. The small GTP-binding Rho proteins are involved in the agonist-induced Ca2+ sensitization of smooth muscle. The action and the expression of Rnd1, a new member of the Rho protein family constitutively bound to GTP, has been studied in rat smooth m
Autor:
Pierre Chardin
Publikováno v:
médecine/sciences. 24:205-207