Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Pierre C McCarthy"'
Autor:
Matthias Gaestel, J. Simon C. Arthur, Corinna Greger, Iain R. Phair, Pierre C McCarthy, Andrew R. Clark, Victoria A. McGuire, Katerina Pardali
Publikováno v:
Immunology and Cell Biology
IL‐33 is an IL‐1‐related cytokine that can act as an alarmin when released from necrotic cells. Once released, it can target various immune cells including mast cells, innate lymphoid cells and T cells to elicit a Th2‐like immune response. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa54fa5c8538c3424ad5cdade4bec2ec
https://doi.org/10.1111/imcb.12200
https://doi.org/10.1111/imcb.12200
Autor:
Ram K C Venigalla, Victoria A. McGuire, Laste Stojanovski, Rosemary G. Clarke, Rachel Toth, Janet C. Patterson-Kane, J. Simon C. Arthur, Ayaz Najafov, Frederick R. C. Simeons, Pierre C McCarthy
Publikováno v:
The EMBO Journal
Phosphoinositide-dependent kinase-1 (PDK1) controls the activation of a subset of AGC kinases. Using a conditional knockout of PDK1 in haematopoietic cells, we demonstrate that PDK1 is essential for B cell development. B-cell progenitors lacking PDK1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db6fcd185d0b5786a6f98ae17371551d
https://doi.org/10.1038/emboj.2013.40
https://doi.org/10.1038/emboj.2013.40
Autor:
Kirsty F. MacKenzie, Shaista Naqvi, Pierre C McCarthy, Gesa Nöehren, Patrick G. A. Pedrioli, Geoff J. Barton, Manikhandan Mudaliar, Yosua Adi Kristariyanto, Alan R. Prescott, Rachel Toth, Kristopher Clark, Victoria A. McGuire, J. Simon C. Arthur, Michael J. Pattison, Mirjam W. M. Van Den Bosch
The polarization of macrophages into a regulatory-like phenotype and the production of IL-10 plays an important role in the resolution of inflammation. We show in this study that PGE2, in combination with LPS, is able to promote an anti-inflammatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35909719cf4f5bca3dc2f7b2e8cbcb32
https://europepmc.org/articles/PMC3620524/
https://europepmc.org/articles/PMC3620524/
