Zobrazeno 1 - 10
of 435
pro vyhledávání: '"Pierre Alain Carrupt"'
Autor:
Bernard Testa, Giulia Caron, Patrizia Crivori, Sébastien Rey, Marianne Reist, Pierre Alain Carrupt
Publikováno v:
CHIMIA, Vol 54, Iss 11 (2000)
This minireview presents some recent work, mainly from the authors' laboratory, aimed at improving the interpretability and predictivity of structure-pharmacokinetic relationships. The first part of the text discusses the intermolecular forces and in
Externí odkaz:
https://doaj.org/article/0c9b8e36fd8d408bb95d45ded6d51613
Autor:
Guillaume Marti, Sylvain Schnee, Yannis Andrey, Claudia Simoes-Pires, Pierre-Alain Carrupt, Jean-Luc Wolfender, Katia Gindro
Publikováno v:
Molecules, Vol 19, Iss 9, Pp 14004-14021 (2014)
UV-C radiation is known to induce metabolic modifications in plants, particularly to secondary metabolite biosynthesis. To assess these modifications from a global and untargeted perspective, the effects of the UV-C radiation of the leaves of three d
Externí odkaz:
https://doaj.org/article/6c927338704945d9bb81ab8f90ff001b
Autor:
Lionel Sacconnay, Melissa Angleviel, Giuseppe Marco Randazzo, Marcos Marçal Ferreira Queiroz, Emerson Ferreira Queiroz, Jean-Luc Wolfender, Pierre-Alain Carrupt, Alessandra Nurisso
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 2, p e2689 (2014)
BACKGROUND: The silent-information regulator 2 proteins, otherwise called sirtuins, are currently considered as emerging anti-parasitic targets. Nicotinamide, a pan-sirtuin inhibitor, is known to cause kinetoplast alterations and the arrested growth
Externí odkaz:
https://doaj.org/article/f704bf9983f84b8698f64c03a2e2ad8a
Autor:
Jean-Luc Wolfender, Paul Herrling, Pierre-Alain Carrupt, Alexander D. Crawford, Elisabeth Ngo Bum, Maxime Jacmin, Charlotte Petit, Ivan Slacanin, Théo Brillatz, Emerson Ferreira Queiroz, Laurence Marcourt
Publikováno v:
Phytomedicine : international journal of phytotherapy and phytopharmacology. 70
Background Epilepsy is a chronic neurological disorder affecting more than 50 million people worldwide, of whom 80% live in low- and middle-income countries. Due to the limited availability of antiseizure drugs (ASDs) in these countries, medicinal pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f50499bb5b0bcb3178469db789ba7103
https://pubmed.ncbi.nlm.nih.gov/32302934
https://pubmed.ncbi.nlm.nih.gov/32302934
Publikováno v:
European Journal of Pharmaceutical Sciences, Vol. 97 (2017) pp. 143-150
The parallel artificial membrane permeability assay (PAMPA) is a high-throughput screening (HTS) technique developed to predict passive permeability through numerous different biological membranes, such as the gastrointestinal tract (GIT), the blood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f604539a929475c8849950f8ec41ca14
https://doi.org/10.1016/j.ejps.2016.11.001
https://doi.org/10.1016/j.ejps.2016.11.001
The molecular lipophilicity potential (MLP) is a well-established method to calculate and visualize lipophilicity on molecules. We are here introducing a new computational tool named MLP Tools, written in the programming language Python, and conceive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::228d5105ef37a36b9aede20b3562a533
http://doc.rero.ch/record/324915/files/10822_2014_Article_9744.pdf
http://doc.rero.ch/record/324915/files/10822_2014_Article_9744.pdf
Autor:
William Schuler, Nils Oberhauser, Sophie Martel, Frédéric Begnaud, Fabrice Gillerat, Pierre-Alain Carrupt, Alessandra Nurisso
Publikováno v:
Analytica Chimica Acta. 915:90-101
Lipophilicity is of crucial importance in many fields including pharmaceutical, environmental, cosmetic and food industries. Whereas different experimental strategies have been developed for rapid lipophilicity determination of new chemical entities,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7df082bff87d397adc58b34bb9fdda3
https://doi.org/10.1016/j.aca.2016.02.005
https://doi.org/10.1016/j.aca.2016.02.005
Autor:
Carolina dos Santos Passos, Pierre-Alain Carrupt, Daumantas Matulis, Alessandra Nurisso, Jelena Jachno, Lucie Ryckewaert, Claudia A. Simões-Pires, Lionel Sacconnay, Giuseppe Marco Randazzo, Vilma Michailovienė, Asta Zubrienė, Charlotte Petit
Publikováno v:
European Journal of Pharmaceutical Sciences. 85:59-67
Sirtuins (SIRTs) are a family of enzymes able to catalyze the deacetylation of the N-acetyl lysines of both histone and non-histone substrates. Inhibition of SIRTs catalytic activity was recently reported in the literature as being beneficial in huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6710c460f67e09d672fc1ec83841eb10
https://doi.org/10.1016/j.ejps.2016.01.010
https://doi.org/10.1016/j.ejps.2016.01.010
Autor:
Laurent Geiser, Julie Schappler, Pierre-Alain Carrupt, Josiane Prat, Yveline Henchoz, Jean-Luc Veuthey
Publikováno v:
Analytical and Bioanalytical Chemistry, Vol. 389, No 6 (2007) pp. 1869-78
A rapid and universal capillary zone electrophoresis (CZE) method was developed to determine the dissociation constants (pK a) of the 20 standard proteogenic amino acids. Since some amino acids are poorly detected by UV, capacitively coupled contactl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2b5fbf957bd923385aa45900f0fad7d
http://doc.rero.ch/record/314383/files/216_2007_Article_1568.pdf
http://doc.rero.ch/record/314383/files/216_2007_Article_1568.pdf
Autor:
Philippe Vayer, Jean Michel Scherrmann, Hélène Chapy, Pierre-Alain Carrupt, Gabriele Cruciani, Laura Goracci, Salvatore Cisternino, Xavier Declèves, Yannick Parmentier
Publikováno v:
British Journal of Pharmacology. 172:4888-4904
Background and purpose An influx drug/proton antiporter of unknown structure has been functionally demonstrated at the blood-brain barrier. This transporter, which handles some psychoactive drugs like diphenhydramine, clonidine, oxycodone, nicotine a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98077803c8097742bb30388605860f79
https://doi.org/10.1111/bph.13258
https://doi.org/10.1111/bph.13258