Left ventricular ejection fraction decrease related to BRAF and/or MEK inhibitors in metastatic melanoma patients: A retrospective analysis

Autor: Mathilde Berger, Mona Amini‐Adlé, Delphine Maucort‐Boulch, Philip Robinson, Luc Thomas, Stéphane Dalle, Pierre‐Yves Courand

Publikováno v: Cancer Medicine, Vol 9, Iss 8, Pp 2611-2620 (2020)

Abstract BRAF and MEKis have revolutionized the management of BRAFV600‐mutated melanoma patients. Left ventricular ejection fraction decrease (LVEF‐D) related to these treatments has not been thoroughly evaluated to date. The main objective of th

Externí odkaz: https://doaj.org/article/ecce891d2f4d40d98a56ce56d1a2b7c1

Abdominal Aortic Calcifications Influences the Systemic and Renal Hemodynamic Response to Renal Denervation in the DENERHTN (Renal Denervation for Hypertension) Trial

Autor: Pierre‐Yves Courand, Helena Pereira, Costantino Del Giudice, Philippe Gosse, Matthieu Monge, Guillaume Bobrie, Pascal Delsart, Claire Mounier‐Vehier, Pierre Lantelme, Thierry Denolle, Caroline Dourmap, Jean Michel Halimi, Xavier Girerd, Patrick Rossignol, Faiez Zannad, Olivier Ormezzano, Bernard Vaisse, Daniel Herpin, Jean Ribstein, Beatrice Bouhanick, Jean‐Jacques Mourad, Emile Ferrari, Gilles Chatellier, Marc Sapoval, Arshid Azarine, Michel Azizi

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 10 (2017)

BackgroundThe DENERHTN (Renal Denervation for Hypertension) trial confirmed the efficacy of renal denervation (RDN) in lowering daytime ambulatory systolic blood pressure when added to standardized stepped‐care antihypertensive treatment (SSAHT) fo

Externí odkaz: https://doaj.org/article/a385a9cc26eb49e884e4ec377f8fb877

Data from A Genetic Mouse Model Recapitulates Immune Checkpoint Inhibitor–Associated Myocarditis and Supports a Mechanism-Based Therapeutic Intervention

Autor: James P. Allison, Javid J. Moslehi, Justin M. Balko, Joe-Elie Salem, Padmanee Sharma, Lauren I.R. Ehrlich, Jing Wang, Yang Zhao, Xiayu Rao, Oluwatomisin T. Atolagbe, Yu Li, Jayashree Srinivasan, Bjorn C. Knollmann, Matthew J. Wleklinski, Benedicte Lebrun-Vignes, Lauren E. Himmel, James J. Mancuso, Pierre-Yves Courand, Lorenz Lehmann, Elizabeth Whitley, Douglas B. Johnson, Elizabeth C. Wescott, Elles M. Screever, Nana-Ama A.S. Anang, Margaret L. Axelrod, Wouter C. Meijers, Spencer C. Wei

Immune checkpoint inhibitors (ICI) targeting CTLA4 or PD-1/PD-L1 have transformed cancer therapy but are associated with immune-related adverse events, including myocarditis. Here, we report a robust preclinical mouse model of ICI-associated myocardi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ac086af2e9029b3bb7219798b72ea281
https://doi.org/10.1158/2159-8290.c.6547996.v1

Fractional Flow Reserve to Guide Treatment of Patients With Multivessel Coronary Artery Disease

Autor: Gilles Rioufol, François Dérimay, François Roubille, Thibault Perret, Pascal Motreff, Denis Angoulvant, Yves Cottin, Ludovic Meunier, Laura Cetran, Guillaume Cayla, Brahim Harbaoui, Jean-Yves Wiedemann, Éric Van Belle, Christophe Pouillot, Nathalie Noirclerc, Jean-François Morelle, François-Xavier Soto, Christophe Caussin, Bernard Bertrand, Thierry Lefèvre, Patrick Dupouy, Pierre-François Lesault, Franck Albert, Olivier Barthelemy, René Koning, Laurent Leborgne, Pierre Barnay, Philippe Chapon, Sébastien Armero, Antoine Lafont, Christophe Piot, Camille Amaz, Bernadette Vaz, Lakhdar Benyahya, Yvonne Varillon, Michel Ovize, Nathan Mewton, Gérard Finet, Alexandre Fournier, Geneviève Jarry, François Leleu, Dorothée Malaquin, Anfani Mirode, Loïc Belle, Lionel Mangin, Jean-Lou Hirsch, Marc Metge, Michel Pansiery, FrançoisXavier Soto, Antoine Boge, Kamel HadjHamou, Ichem Miliani, Guillaume Molins, Stéphane Mourot, Marion Pelletier, Olivier Ressencourt, Frédéric Schaad, Pierre Coste, Warren Chasseriaud, Pierre Poustis, Jean-Francois Morelle, Thibaud Demicheli, Grégroire Range, Christophe Thuaire, Nicolas Barber-Chamoux, Nicolas Combaret, Guilhem Malclès, Géraud Souteyrand, Philippe Buffet, Aurélie Gudjonvick, Isabelle L’Huillier, Luc Lorgis, Carole Richard, Gilles Baronne-Rochette, Hélène Bouvaist, Stéphanie Marlière, Olivier Ormezzano, Gérald Vanzetto, Charlotte Trouillet, Yann Valy, Eric VanBelle, Christophe Bauters, Cédric Delhaye, Gilles Lemesle, Riadh Rihani, Pierre Graux, Jean-Michel Lemahieu, Cyril Besnard, Pierre-Yves Courand, Raphaël Dauphin, Pierre Lantelme, Jean-Raymond Caignault, Olivier Dubreuil, Sylvain Ranc, Bernard Ritz, Cyrille Bergerot, Thomas Bochaton, Eric Bonnefoy-Cudraz, Didier Bresson, Julie Dementhon, François Derimay, Lisa Green, Cyril Prieur, Ingrid Sanchez, Oualid Zouaghi, Sébastien Arméro, Hakim Ben-Amer, Bernard Chevalier, Philippe Garot, Thomas Hovasse, Yves Louvard, Marie-Claude Morice, Oscar Tavolaro, Thierry Unterseeh, DinhThienTri Cung, Jean-Christophe Macia, Gilles Levy, Olivier Roth, Laurent Jacquemin, Luc Cornillet, Bertrand Ledermann, Laurent Schmutz, Nicole Karam, Saliha Rahal, Nicolas Amabile, Philippe Girard, Aurélie Veugeois, Olivier Barthélémy, Jean-Philippe Collet, Gilles Montalescot, Jacques Berland, Matthieu Godin, Quentin Landolff, Bilel Zoghlami, Karim Bougrini, Christophe Geyer, Jens Glanenapp, Patrick Mascarel, Geoffray Rambaud, Richard ViFane, Bernard Desveaux, Fabrice Ivanes, Gérard Pacouret, Laurent-Emmanuel Quilliet, Christophe SaintEtienne, Christophe Bretelle, Stanislas Champin

Publikováno v: Journal of the American College of Cardiology
Journal of the American College of Cardiology, Elsevier, 2021, 78 (19), pp.1875-1885. ⟨10.1016/j.jacc.2021.08.061⟩

Background There is limited evidence that fractional flow reserve (FFR) is effective in guiding therapeutic strategy in multivessel coronary artery disease (CAD) beyond prespecified percutaneous coronary intervention or coronary graft surgery candida

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dedce2fa1ec25cab4064bffe937a1860
https://doi.org/10.1016/j.jacc.2021.08.061

Hypertension management: Back to the future

Autor: Pierre, Lantelme, Brahim, Harbaoui, Pierre-Yves, Courand

Publikováno v: Archives of Cardiovascular Diseases. 115:249-251

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7977eb0212ed53c8e734934e70b33cb
https://doi.org/10.1016/j.acvd.2022.02.009