Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Pierre‐Alexandre Driguez"'
Autor:
Christophe Boudesco, Annelies Nonneman, Alessandro Cinti, Paola Picardi, Loredana Redaelli, Sofie Swijsen, Julian Roewe, Peter Reinhardt, Melanie Ibach, Jochen Walter, Jennifer M. Pocock, Yi Ren, Pierre‐Alexandre Driguez, Gihad Dargazanli, Stephanie Eyquem, Jonathan Proto, Amilcar Flores‐Morales, Laurent Pradier
Publikováno v:
Glia. 70:2290-2308
The receptor Triggering Receptor Expressed on Myeloid cells 2 (TREM2) is associated with several neurodegenerative diseases including Alzheimer's Disease and TREM2 stimulation represents a novel therapeutic opportunity. TREM2 can be activated by anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d311b1fce49c62c905f88f9de83f3859
https://doi.org/10.1002/glia.24252
https://doi.org/10.1002/glia.24252
Publikováno v:
The Journal of organic chemistry. 85(24)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c83049b0530a78fe543933515543f535
https://pubmed.ncbi.nlm.nih.gov/33334105
https://pubmed.ncbi.nlm.nih.gov/33334105
Publikováno v:
Protecting Groups
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68a2dec43a6410a2e1404721b9d29226
https://doi.org/10.1002/9783527697014.ch17
https://doi.org/10.1002/9783527697014.ch17
Autor:
Olivier Berteau, Pierre-Alexandre Driguez, Jonathan E. Ulmer, Annie Malleron, Corine Sandström, Eric Morssing Vilén, Ramesh Babu Namburi, Alhosna Benjdia, Julie Beneteau, Karine Descroix, Christine Le Narvor, Lassalle Gilbert, Dorothe Spillmann, David Bonnaffé
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2014, 289 (35), pp.24289-24303. ⟨10.1074/jbc.M114.573303⟩
Journal of Biological Chemistry 35 (289), 24289-24303. (2014)
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2014, 289 (35), pp.24289-24303. ⟨10.1074/jbc.M114.573303⟩
Journal of Biological Chemistry 35 (289), 24289-24303. (2014)
Background: Sulfatases are emerging as key adaptive tools of commensal bacteria to their host. Results: The first bacterial endo-O-sulfatase and three exo-O-sulfatases from the human commensal Bacteroides thetaiotaomicron, specific for glycosaminogly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04780036118e2b0a8f892598b14a6a55
https://doi.org/10.1074/jbc.m114.573303
https://doi.org/10.1074/jbc.m114.573303
Autor:
Mouna, Mothéré, Dominique, Singabraya, Pierre-Alexandre, Driguez, Fernando, Siñeriz, Dulce, Papy-Garcia
Publikováno v:
Journal of molecular recognition : JMR. 30(3)
Heparan sulfates are complex polysaccharides belonging to the family of glycosaminoglycans that participate to the regulation of cell behavior and tissue homeostasis. The biological activities conferred to heparan sulfates are largely dependent on th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d2412caf966827ff078ff9cd6282ac79
https://pubmed.ncbi.nlm.nih.gov/27790778
https://pubmed.ncbi.nlm.nih.gov/27790778
Autor:
Jean-Marc Herbert, José Kovensky, Jean-Maurice Mallet, Maurice Petitou, Jean-Pascal Herault, Jacques Esnault, Pierre Sinaÿ, Pierre-Alexandre Driguez, Philippe Sizun
Publikováno v:
Scopus-Elsevier
L-iduronic acid, a conformationally flexible monosaccharide, imparts a remarkable protein adaptability to the glycosaminoglycans heparin, heparan sulfate, and dermatan sulfate. The pentasaccharide representing the antithrombin binding site of heparin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d439caa17203c9f8840fc887bfaf47f1
https://doi.org/10.1002/1099-0690(200211)2002:21<3595::aid-ejoc3595>3.0.co
https://doi.org/10.1002/1099-0690(200211)2002:21<3595::aid-ejoc3595>3.0.co
Autor:
C. Gaich, Françoise Bono, J. M. Herbert, Petitou Maurice, Pierre-Alexandre Driguez, J. P. Hérault, P. Duchaussoy
Publikováno v:
Thrombosis and Haemostasis. 88:432-435
SummaryWe investigated the effect of various oligosaccharides (OS) on the inhibition of factor IXa by antithrombin (AT) in a purified system. The OS comprised the AT-binding pentasaccharide sequence prolonged by saccharide chains with various lengths
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9d81d8b66b29f57646d64039e724bf4
https://doi.org/10.1055/s-0037-1613234
https://doi.org/10.1055/s-0037-1613234
Publikováno v:
The journal of physical chemistry. B. 118(41)
NMR and density functional theory (DFT) have afforded detailed information on the molecular geometry and spin-spin coupling constants of a trisaccharide from the heparin repeating-sequence. The fully optimized molecular structures of two trisaccharid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6fe996bee36a016e260d7b2b78f0d87
https://pubmed.ncbi.nlm.nih.gov/25254635
https://pubmed.ncbi.nlm.nih.gov/25254635
Publikováno v:
ChemInform. 45
Covering: up to November 2013. Heparin and heparan sulfate are natural polysaccharides with strong structural variations, which are responsible for their numerous specific biological properties. One key target of heparin, among others, is antithrombi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23c8d24cfa3e43eb5668b20ea10d67e6
https://doi.org/10.1002/chin.201439273
https://doi.org/10.1002/chin.201439273
Publikováno v:
Natural product reports. 31(8)
Covering: up to November 2013. Heparin and heparan sulfate are natural polysaccharides with strong structural variations, which are responsible for their numerous specific biological properties. One key target of heparin, among others, is antithrombi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5d491d07d705cd6d53e3fc8bb4edcae
https://pubmed.ncbi.nlm.nih.gov/24705477
https://pubmed.ncbi.nlm.nih.gov/24705477