Zobrazeno 1 - 10
of 398
pro vyhledávání: '"Pierre, Validire"'
Autor:
Priyanka Devi-Marulkar, Solène Fastenackels, Pierre Karapentiantz, Jérémy Goc, Claire Germain, Hélène Kaplon, Samantha Knockaert, Daniel Olive, Marylou Panouillot, Pierre Validire, Diane Damotte, Marco Alifano, Juliette Murris, Sandrine Katsahian, Myriam Lawand, Marie-Caroline Dieu-Nosjean
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-16 (2022)
Regulatory T cells (Tregs) have similar immune profiles in tertiary lymphoid structures of lung cancer and non-TLS areas, with tumor-infiltrating Tregs found to inhibit the proliferation and cytokine secretion of CD4 + conventional T cells.
Externí odkaz:
https://doaj.org/article/6843b8158e4442199fa24d4eee02cf0d
Autor:
Marine Leclerc, Elodie Voilin, Gwendoline Gros, Stéphanie Corgnac, Vincent de Montpréville, Pierre Validire, Georges Bismuth, Fathia Mami-Chouaib
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Neuropilin-1 (Nrp-1) is a marker for CD4 + regulatory T cells. Here the authors show that Nrp-1 is co-expressed with PD-1 on a subset of CD8 tumour-infiltrating T lymphocytes and inhibits T-cell migration and cytotoxicity when bound by its ligand sem
Externí odkaz:
https://doaj.org/article/2c3cddaf2f6c490e988bea7275b3ada4
Autor:
Aurélie Durgeau, Yasemin Virk, Gwendoline Gros, Elodie Voilin, Stéphanie Corgnac, Fayçal Djenidi, Jérôme Salmon, Julien Adam, Vincent de Montpréville, Pierre Validire, Soldano Ferrone, Salem Chouaib, Alexander Eggermont, Jean-Charles Soria, François Lemonnier, Eric Tartour, Nathalie Chaput, Benjamin Besse, Fathia Mami-Chouaib
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Tumours can escape CD8 T-cell immunity by down-regulating antigen presentation machinery components, such as TAP. Here the authors describe tumour antigenic peptides processed by TAP-independent and -dependent pathways and show in mouse models that t
Externí odkaz:
https://doaj.org/article/7f6d68fe1b834788afc4ae75e5477438
Autor:
Claire Germain, Priyanka Devi-Marulkar, Samantha Knockaert, Jérôme Biton, Hélène Kaplon, Laïla Letaïef, Jérémy Goc, Agathe Seguin-Givelet, Dominique Gossot, Nicolas Girard, Pierre Validire, Marine Lefèvre, Diane Damotte, Marco Alifano, François M. Lemoine, Keith E. Steele, Jean-Luc Teillaud, Scott A. Hammond, Marie-Caroline Dieu-Nosjean
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The presence of tertiary lymphoid structures (TLS) in the tumor microenvironment is associated with better clinical outcome in many cancers. In non-small cell lung cancer (NSCLC), we have previously showed that a high density of B cells within TLS (T
Externí odkaz:
https://doaj.org/article/757b1a291fa64d989f66f304930a5ace
Autor:
Stéphanie Corgnac, Ines Malenica, Laura Mezquita, Edouard Auclin, Elodie Voilin, Jamila Kacher, Heloise Halse, Laetitia Grynszpan, Nicolas Signolle, Thibault Dayris, Marine Leclerc, Nathalie Droin, Vincent de Montpréville, Olaf Mercier, Pierre Validire, Jean-Yves Scoazec, Christophe Massard, Salem Chouaib, David Planchard, Julien Adam, Benjamin Besse, Fathia Mami-Chouaib
Publikováno v:
Cell Reports Medicine, Vol 1, Iss 7, Pp 100127- (2020)
Summary: Accumulation of CD103+CD8+ resident memory T (TRM) cells in human lung tumors has been associated with a favorable prognosis. However, the contribution of TRM to anti-tumor immunity and to the response to immune checkpoint blockade has not b
Externí odkaz:
https://doaj.org/article/915c3d3910d847f0928d99be365b54ff
Autor:
Jules Russick, Pierre-Emmanuel Joubert, Mélanie Gillard-Bocquet, Carine Torset, Maxime Meylan, Florent Petitprez, Marie-Agnes Dragon-Durey, Solenne Marmier, Aditi Varthaman, Nathalie Josseaume, Claire Germain, Pierre Validire, Ludovic Fournel, Audrey Lupo
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Natural killer (NK) cells play a crucial role in tumor immunosurveillance through their cytotoxic effector functions and their capacity to interact with other immune cells to build a coordinated antitumor immune response. Emerging data rev
Externí odkaz:
https://doaj.org/article/66cfd0aa9b7a4ab3ad675fae3785d405
Autor:
Alexandre Ivagnès, Meriem Messaoudene, Gautier Stoll, Bertrand Routy, Aurélie Fluckiger, Takahiro Yamazaki, Kristina Iribarren, Connie P. M. Duong, Laetitia Fend, Anne Caignard, Isabelle Cremer, Axel LeCesne, Julien Adam, Charles Honoré, Olivier Mir, Loïc Chaigneau, Anne Berger, Pierre Validire, Christos Christidis, Valérie Le Brun-Ly, Mark J. Smyth, Xavier Mariette, Benoît L. Salomon, Guido Kroemer, Sylvie Rusakiewicz, Laurence Zitvogel
Publikováno v:
OncoImmunology, Vol 7, Iss 12 (2018)
Natural Killer (NK) cells control metastatic dissemination of murine tumors and are an important prognostic factor in several human malignancies. However, tumor cells hijack many of the NK cell functional features compromising their tumoricidal activ
Externí odkaz:
https://doaj.org/article/827dd603e2a54f17ad4e4777d94b2028
Autor:
Lubka T. Roumenina, Wolf H. Fridman, Catherine Sautès-Fridman, Isabelle Cremer, Veronique Fremeaux-Bacchi, Diane Damotte, Rafael Sanchez-Salas, Xavier Cathelineau, Pierre Validire, Geraldine Perkins, Yann A. Vano, Arnaud Mejean, Stephane M. Oudard, Virginie Verkarre, Maxime Meylan, Antoine Bougouin, Guillaume Lacroix, Anne Grunenwald, Victoria Poillerat, Tania Robe-Rybkine, Christine Gaboriaud, Marie-Agnès Dragon-Durey, Jules Russick, Margot Revel, Marie V. Daugan
Supplementary Figures 1-15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fb295f5109a7bea61aaebb35b149081
https://doi.org/10.1158/2326-6066.22544075
https://doi.org/10.1158/2326-6066.22544075
Autor:
Lubka T. Roumenina, Wolf H. Fridman, Catherine Sautès-Fridman, Isabelle Cremer, Veronique Fremeaux-Bacchi, Diane Damotte, Rafael Sanchez-Salas, Xavier Cathelineau, Pierre Validire, Geraldine Perkins, Yann A. Vano, Arnaud Mejean, Stephane M. Oudard, Virginie Verkarre, Maxime Meylan, Antoine Bougouin, Guillaume Lacroix, Anne Grunenwald, Victoria Poillerat, Tania Robe-Rybkine, Christine Gaboriaud, Marie-Agnès Dragon-Durey, Jules Russick, Margot Revel, Marie V. Daugan
The complement system plays a complex role in cancer. In clear cell renal cell carcinoma (ccRCC), local production of complement proteins drives tumor progression, but the mechanisms by which they do this are poorly understood. We found that compleme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a015140b9f14187f155016759ed8b80
https://doi.org/10.1158/2326-6066.c.6550523.v1
https://doi.org/10.1158/2326-6066.c.6550523.v1
Autor:
Lubka T. Roumenina, Wolf H. Fridman, Diane Damotte, Catherine Sautès-Fridman, Marco Alifano, Audrey Mansuet-Lupo, Isabelle Cremer, Mathew C. Pickering, Rafael Sanchez-Salas, Xavier Cathelineau, Pierre Validire, Arnaud Mejean, Stephane Marie Oudard, Virginie Verkarre, Rémi Noé, Nicolas S. Merle, Carine Torset, Tania Robe-Rybkine, Marie-Agnès Dragon-Durey, Romane Thouenon, Margot Revel, Marie V. Daugan
Supplementary figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f0554d14d5298e59232de0abc1787fd
https://doi.org/10.1158/2326-6066.22544516.v1
https://doi.org/10.1158/2326-6066.22544516.v1