Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Pierre, Osteil"'
Autor:
Peter L. H. Newman, Queenie Yip, Pierre Osteil, Tim A. Anderson, Jane Q. J. Sun, Daryan Kempe, Maté Biro, Jae‐Won Shin, Patrick P. L. Tam, Hala Zreiqat
Publikováno v:
Advanced Science, Vol 10, Iss 15, Pp n/a-n/a (2023)
Abstract Multicellular patterning of stem‐cell‐derived tissue models is commonly achieved via self‐organizing activities triggered by exogenous morphogenetic stimuli. However, such tissue models are prone to stochastic behavior, limiting the re
Externí odkaz:
https://doaj.org/article/cbc5e417ee174b0e857397de61f20b58
Autor:
Xiaochen Fan, V Pragathi Masamsetti, Jane QJ Sun, Kasper Engholm-Keller, Pierre Osteil, Joshua Studdert, Mark E Graham, Nicolas Fossat, Patrick PL Tam
Publikováno v:
eLife, Vol 10 (2021)
Protein interaction is critical molecular regulatory activity underlining cellular functions and precise cell fate choices. Using TWIST1 BioID-proximity-labeling and network propagation analyses, we discovered and characterized a TWIST-chromatin regu
Externí odkaz:
https://doaj.org/article/d61b41e7e6734705924eb606b7803440
Autor:
Chang Liu, Ran Wang, Zhisong He, Pierre Osteil, Emilie Wilkie, Xianfa Yang, Jun Chen, Guizhong Cui, Wenke Guo, Yingying Chen, Guangdun Peng, Patrick P.L. Tam, Naihe Jing
Publikováno v:
Stem Cell Reports, Vol 11, Iss 1, Pp 43-57 (2018)
Summary: The molecular mechanism underpinning the specification of the ectoderm, a transient germ-layer tissue, during mouse gastrulation was examined here in a stem cell-based model. We captured a self-renewing cell population with enhanced ectoderm
Externí odkaz:
https://doaj.org/article/1e0ecb938c0c49e383516bae07d49f5a
Publikováno v:
Stem Cell Research, Vol 19, Iss , Pp 104-112 (2017)
The diverse cell states and in vitro conditions for the derivation and maintenance of the mammalian embryo-derived pluripotent stem cells raise the questions of whether there are multiple states of pluripotency of the stem cells of each species, and
Externí odkaz:
https://doaj.org/article/9c6e7e6c097c46d4abd9d4c19f801728
Autor:
Lucie Gavin-Plagne, Florence Perold, Pierre Osteil, Sophie Voisin, Synara Cristina Moreira, Quitterie Combourieu, Véronique Saïdou, Magali Mure, Gérard Louis, Anne Baudot, Samuel Buff, Thierry Joly, Marielle Afanassieff
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 19, p 7285 (2020)
Induced pluripotent stem cells (iPSCs) are obtained by genetically reprogramming adult somatic cells via the overexpression of specific pluripotent genes. The resulting cells possess the same differentiation properties as blastocyst-stage embryonic s
Externí odkaz:
https://doaj.org/article/5cd420e418854966abf739bcbf5eb31d
Autor:
Pierre Osteil, Anaïs Moulin, Claire Santamaria, Thierry Joly, Luc Jouneau, Maxime Aubry, Yann Tapponnier, Catherine Archilla, Barbara Schmaltz-Panneau, Jérôme Lecardonnel, Harmonie Barasc, Nathalie Mouney-Bonnet, Clémence Genthon, Alain Roulet, Cécile Donnadieu, Hervé Acloque, Elen Gocza, Véronique Duranthon, Marielle Afanassieff, Pierre Savatier
Publikováno v:
Stem Cell Reports, Vol 7, Iss 3, Pp 383-398 (2016)
Conventional rabbit embryonic stem cell (ESC) lines are derived from the inner cell mass (ICM) of pre-implantation embryos using methods and culture conditions that are established for primate ESCs. In this study, we explored the capacity of the rabb
Externí odkaz:
https://doaj.org/article/2a1e05f94972454181153ac941f0ce00
Autor:
Georgia R. Kafer, Aisling O’Connor, Samuel Rogers, Pierre Osteil, Christopher B. Nelson, Hilda A. Pickett, Patrick P.L. Tam, Anthony J. Cesare
SummaryReplication stress is an endemic threat to genome stability. For reasons unknown, replication stress response factors become essential during peri-implantation development. This coincides with a stem cell potency switch from the naïve to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f901bfd1143db1bc5986c9ecd408c986
https://doi.org/10.1101/2022.05.12.491744
https://doi.org/10.1101/2022.05.12.491744
Autor:
Pierre, Osteil
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2490
Epiblast stem cells are made from the epiblast of mouse post-implantation embryo. They have been critical in the understanding of mammalian pluripotent stem cells as they share similar properties, such as their incapability to contribute to the forma
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2490
Here we describe a method to engraft epiblast stem cells (EpiSC) into the epiblast of gastrulation-stage mouse embryo to test the lineage propensity acquired by the EpiSCs during in vitro culture under different signaling conditions. After dissection
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2490
The assay for transposase-accessible chromatin using sequencing (ATAC-seq) is used to identify open chromatin regions in cells. This can be used to identify putative regulatory regions, determine dynamics and mechanisms of transcription factors when