Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Pierre, Mattar"'
Autor:
Yacine Touahri, Joseph Hanna, Nobuhiko Tachibana, Satoshi Okawa, Hedy Liu, Luke Ajay David, Thomas Olender, Lakshmy Vasan, Alissa Pak, Dhruv Nimesh Mehta, Vorapin Chinchalongporn, Anjali Balakrishnan, Robert Cantrup, Rajiv Dixit, Pierre Mattar, Fermisk Saleh, Yaroslav Ilnytskyy, Monzur Murshed, Paul E. Mains, Igor Kovalchuk, Julie L. Lefebvre, Hon S. Leong, Michel Cayouette, Chao Wang, Antonio del Sol, Marjorie Brand, Benjamin E. Reese, Carol Schuurmans
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114005- (2024)
Summary: The retina is exquisitely patterned, with neuronal somata positioned at regular intervals to completely sample the visual field. Here, we show that phosphatase and tensin homolog (Pten) controls starburst amacrine cell spacing by modulating
Externí odkaz:
https://doaj.org/article/1882f62fe92d4324a8d569020841d0d4
Autor:
Ivana Herrera, José Alex Lourenço Fernandes, Khatereh Shir-Mohammadi, Jasmine Levesque, Pierre Mattar
Publikováno v:
Cell Death and Disease, Vol 14, Iss 10, Pp 1-12 (2023)
Abstract Neurodegenerative diseases are accompanied by dynamic changes in gene expression, including the upregulation of hallmark stress-responsive genes. While the transcriptional pathways that impart adaptive and maladaptive gene expression signatu
Externí odkaz:
https://doaj.org/article/11bbfd40a3514951b990c111fd4e72b0
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Neural progenitor cells undergo identity transitions during development to ensure the generation different types of neurons and glia in the correct sequence and proportions. A number of temporal identity factors that control these transition
Externí odkaz:
https://doaj.org/article/77cfb57cb22b40868d46df39a2318f29
Autor:
Adele R. Tufford, Jessica R. Onyak, Katelyn B. Sondereker, Jasmine A. Lucas, Aaron M. Earley, Pierre Mattar, Samer Hattar, Tiffany M. Schmidt, Jordan M. Renna, Michel Cayouette
Publikováno v:
Cell Reports, Vol 23, Iss 8, Pp 2416-2428 (2018)
Summary: Newborn neurons follow molecular cues to reach their final destination, but whether early life experience influences lamination remains largely unexplored. As light is among the first stimuli to reach the developing nervous system via intrin
Externí odkaz:
https://doaj.org/article/4f2dfa3ec4924e2ab2837074c56e88d8
Autor:
Camille Boudreau-Pinsonneault, Luke Ajay David, José Alex Lourenço Fernandes, Awais Javed, Michel Fries, Pierre Mattar, Michel Cayouette
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Temporal identity factors are sufficient to reprogram developmental competence of neural progenitors and shift cell fate output, but whether they can also reprogram the identity of terminally differentiated cells is unknown. To address this question,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48a4b30653c68e79c918cee4f0cc3f43
https://doi.org/10.1073/pnas.2122168120
https://doi.org/10.1073/pnas.2122168120
Chromatin remodellers are among the most important risk genes associated with neurodevelopmental disorders (NDDs), however, their functions during brain development are not fully understood. Here, we focused on Sifrim-Hitz-Weiss Syndrome (SIHIWES)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bd938a40937667f2859215f0d4093f5
https://doi.org/10.1101/2023.02.15.528754
https://doi.org/10.1101/2023.02.15.528754
Neurodegenerative diseases are accompanied by dynamic changes in gene expression, including the upregulation of hallmark stress-responsive genes. While the transcriptional pathways that impart adaptive and maladaptive gene expression signatures have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6f876da96bed5cfaa730cbd39b63a52
https://doi.org/10.21203/rs.3.rs-2518916/v1
https://doi.org/10.21203/rs.3.rs-2518916/v1
Autor:
Awais Javed, Pedro L. Santos-França, Pierre Mattar, Allie Cui, Fatima Kassem, Michel Cayouette
Publikováno v:
Development. 150
Temporal identity factors regulate competence of neural progenitors to generate specific cell types in a time-dependent manner, but how they operate remains poorly defined. In the developing mouse retina, the Ikaros zinc-finger transcription factor I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::826c2cf881ac94e9c879053205e5f869
https://doi.org/10.1242/dev.200436
https://doi.org/10.1242/dev.200436
Autor:
Maéva Langouët, Christine Jolicoeur, Awais Javed, Pierre Mattar, Micah D. Gearhart, Stephen P. Daiger, Mette Bertelsen, Lisbeth Tranebjærg, Nanna D. Rendtorff, Karen Grønskov, Catherine Jespersgaard, Rui Chen, Zixi Sun, Hui Li, Najmeh Alirezaie, Jacek Majewski, Vivian J. Bardwell, Ruifang Sui, Robert K. Koenekoop, Michel Cayouette
Publikováno v:
Science Advances. 8
Many transcription factors regulating the production, survival, and function of photoreceptor cells have been identified, but little is known about transcriptional co-regulators in retinal health and disease. Here, we show that BCL6 co-repressor (BCO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76424388799c8d3c69b887e5c430c544
https://doi.org/10.1126/sciadv.abh2868
https://doi.org/10.1126/sciadv.abh2868
Autor:
Maéva, Langouët, Christine, Jolicoeur, Awais, Javed, Pierre, Mattar, Micah D, Gearhart, Stephen P, Daiger, Mette, Bertelsen, Lisbeth, Tranebjærg, Nanna D, Rendtorff, Karen, Grønskov, Catherine, Jespersgaard, Rui, Chen, Zixi, Sun, Hui, Li, Najmeh, Alirezaie, Jacek, Majewski, Vivian J, Bardwell, Ruifang, Sui, Robert K, Koenekoop, Michel, Cayouette
Publikováno v:
Science advances. 8(36)
Many transcription factors regulating the production, survival, and function of photoreceptor cells have been identified, but little is known about transcriptional co-regulators in retinal health and disease. Here, we show that BCL6 co-repressor (BCO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f1f63ad03990eb0680b90dc00d2333e6
https://pubmed.ncbi.nlm.nih.gov/36070393
https://pubmed.ncbi.nlm.nih.gov/36070393