Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Pierre, Charneau"'
Publikováno v:
Expert Review of Vaccines, Vol 23, Iss 1, Pp 674-687 (2024)
Introduction Persistent infections with the human papilloma viruses, HPV16 and HPV18, are associated with multiple cancers. Although prophylactic vaccines that induce HPV-neutralizing antibodies are effective against primary infections, they have no
Externí odkaz:
https://doaj.org/article/4048021770554512a58b0ebca5d6e913
Autor:
Ingrid Fert, Laëtitia Douguet, Benjamin Vesin, Fanny Moncoq, Amandine Noirat, Pierre Authié, Sylvain Ciret, Fabien Le Chevalier, Catherine Blanc, Yakov Vitrenko, Pierre Charneau, Laleh Majlessi, François Anna
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-14 (2024)
Abstract We recently developed an immuno-oncotherapy against human papillomavirus (HPV)-induced tumors based on a lentiviral vector encoding the Early E6 and E7 oncoproteins of HPV16 and HPV18 genotypes, namely “Lenti-HPV-07”. The robust and long
Externí odkaz:
https://doaj.org/article/5be4580b01cc47c9a59f64f70f8a2add
Autor:
Laëtitia Douguet, Ingrid Fert, Jodie Lopez, Benjamin Vesin, Fabien Le Chevalier, Fanny Moncoq, Pierre Authié, Trang‐My Nguyen, Amandine Noirat, Fabien Névo, Catherine Blanc, Maryline Bourgine, David Hardy, François Anna, Laleh Majlessi, Pierre Charneau
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 10, Pp n/a-n/a (2023)
Abstract Human papillomavirus (HPV) infections are the cause of all cervical and numerous oropharyngeal and anogenital cancers. The currently available HPV vaccines, which induce neutralizing antibodies, have no therapeutic effect on established tumo
Externí odkaz:
https://doaj.org/article/322a19d1d52f4623ae50d523d363e035
Autor:
Kirill Nemirov, Pierre Authié, Philippe Souque, Fanny Moncoq, Amandine Noirat, Catherine Blanc, Maryline Bourgine, Laleh Majlessi, Pierre Charneau
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Dengue virus (DENV) is responsible for approximately 100 million cases of dengue fever annually, including severe forms such as hemorrhagic dengue and dengue shock syndrome. Despite intensive vaccine research and development spanning several decades,
Externí odkaz:
https://doaj.org/article/089c1dcdf90542268011165d1f989167
Autor:
Min‐Wen Ku, Pierre Authié, Maryline Bourgine, François Anna, Amandine Noirat, Fanny Moncoq, Benjamin Vesin, Fabien Nevo, Jodie Lopez, Philippe Souque, Catherine Blanc, Ingrid Fert, Sébastien Chardenoux, llta Lafosse, Delphine Cussigh, David Hardy, Kirill Nemirov, Françoise Guinet, Francina Langa Vives, Laleh Majlessi, Pierre Charneau
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 12, Pp 1-21 (2021)
Abstract COVID‐19 vaccines already in use or in clinical development may have reduced efficacy against emerging SARS‐CoV‐2 variants. In addition, although the neurotropism of SARS‐CoV‐2 is well established, the vaccine strategies currently
Externí odkaz:
https://doaj.org/article/e281ac5ccf5c4d798e95aba80cc3ff64
Autor:
Min Wen Ku, Pierre Authié, Fabien Nevo, Philippe Souque, Maryline Bourgine, Marta Romano, Pierre Charneau, Laleh Majlessi
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
Ku et al. report a lentiviral (LV) vector system in which expression of vaccine antigens is driven by β2-microglobulin (β2m) promoter. Conducting comparative studies in mice and rats, they find that LV-based vaccine outperforms the ‘gold-standard
Externí odkaz:
https://doaj.org/article/fe683d23065d4838988c80289e525fa0
Autor:
Jodie Lopez, François Anna, Pierre Authié, Alexandre Pawlik, Min-Wen Ku, Catherine Blanc, Philippe Souque, Fanny Moncoq, Amandine Noirat, David Hardy, Wladimir Sougakoff, Roland Brosch, Françoise Guinet, Pierre Charneau, Laleh Majlessi
Publikováno v:
Cell Reports, Vol 40, Iss 4, Pp 111142- (2022)
Summary: Lentiviral vectors (LVs) are highly efficient at inducing CD8+ T cell responses. However, LV-encoded antigens are processed inside the cytosol of antigen-presenting cells, which does not directly communicate with the endosomal major histocom
Externí odkaz:
https://doaj.org/article/464bede2d4844e65b8993381d9865e5e
Autor:
Stéphane Le Vu, Gabrielle Jones, François Anna, Thierry Rose, Jean-Baptiste Richard, Sibylle Bernard-Stoecklin, Sophie Goyard, Caroline Demeret, Olivier Helynck, Nicolas Escriou, Marion Gransagne, Stéphane Petres, Corinne Robin, Virgile Monnet, Louise Perrin de Facci, Marie-Noelle Ungeheuer, Lucie Léon, Yvonnick Guillois, Laurent Filleul, Pierre Charneau, Daniel Lévy-Bruhl, Sylvie van der Werf, Harold Noel
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-7 (2021)
The percentage of national populations infected during the first stages of the COVID-19 pandemic are unclear owing to limited early testing. Here the authors provide a nation-wide prevalence study of SARS-CoV-2 antibodies in France from the first wav
Externí odkaz:
https://doaj.org/article/53e4ab675fd743dc9696f2feeb701868
Publikováno v:
Pharmaceutics, Vol 15, Iss 3, p 846 (2023)
Lentiviral vectors are among the most effective viral vectors for vaccination. In clear contrast to the reference adenoviral vectors, lentiviral vectors have a high potential for transducing dendritic cells in vivo. Within these cells, which are the
Externí odkaz:
https://doaj.org/article/3ee2c09b5cde4f6db1bc22825581a6d8
Autor:
Makoto Miyara, Melissa Saichi, Delphine Sterlin, François Anna, Stéphane Marot, Alexis Mathian, Mo Atif, Paul Quentric, Audrey Mohr, Laetitia Claër, Christophe Parizot, Karim Dorgham, Hans Yssel, Jehane Fadlallah, Thibaut Chazal, Julien Haroche, Charles-Edouard Luyt, Julien Mayaux, Alexandra Beurton, Neila Benameur, David Boutolleau, Sonia Burrel, Sophia de Alba, Sasi Mudumba, Rick Hockett, Cary Gunn, Pierre Charneau, Vincent Calvez, Anne-Geneviève Marcelin, Alain Combes, Alexandre Demoule, Zahir Amoura, Guy Gorochov
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The capacity of pre-existing immunity to human common coronaviruses (HCoV) to cross-protect against de novo COVID-19is yet unknown. In this work, we studied the sera of 175 COVID-19 patients, 76 healthy donors and 3 intravenous immunoglobulins (IVIG)
Externí odkaz:
https://doaj.org/article/406cda8e8a9d4a24affbdc37b4446aec