Výsledky vyhledávání - "Pierre, Brissot"

Akademický článek

What’s Important and New in Hemochromatosis?

Publikováno v: Clinical Hematology International, Vol 2, Iss 4 (2020)

Major advances in the understanding of genetic iron overload have led to a clarification of the nosology and terminology of the related diseases. The term hemochromatosis should be reserved to the entities where iron overload is related to hepcidin d

Externí odkaz: https://doaj.org/article/8e24c150d1454d568fc8d4b7602f5118

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Akademický článek

Autor: Wei Zhang, Xiaoming Wang, Weijia Duan, Anjian Xu, Xinyan Zhao, Jian Huang, Hong You, Pierre Brissot, Xiaojuan Ou, Jidong Jia

Publikováno v: Frontiers in Genetics, Vol 11 (2020)

HFE-related Hemochromatosis is the most common genetic iron overload disease in European populations, particularly of Nordic or Celtic ancestry. It is reported that the HFE p.C282Y mutation is present in 1/10 people of northern European descent, resu

Externí odkaz: https://doaj.org/article/c194f4d027a148b98e5e2f4bdd5ae695

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Akademický článek

Quality of life scores differs between genotypic groups of patients with suspected hereditary hemochromatosis

Autor: Paula Fernanda Silva Fonseca, Rodolfo Delfini Cançado, Flavio Augusto Naoum, Carla Luana Dinardo, Guilherme Henrique Hencklain Fonseca, Sandra Fatima Menosi Gualandro, José Eduardo Krieger, Alexandre Costa Pereira, Pierre Brissot, Paulo Caleb Junior Lima Santos

Publikováno v: BMC Medical Genetics, Vol 19, Iss 1, Pp 1-5 (2018)

Abstract Background Hereditary hemochromatosis (HH) encompasses a group of autosomal recessive disorders mainly characterized by enhanced intestinal absorption of iron and its accumulation in parenchymal organs. HH diagnosis is based on iron biochemi

Externí odkaz: https://doaj.org/article/43e123d81f7c4a6bb4f7d80d50b831ff

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Iron and platelets: A subtle, under‐recognized relationship

Autor: Eolia Brissot, Pierre Brissot, Marie-Bérengère Troadec, Olivier Loréal

Publikováno v: American Journal of Hematology
American Journal of Hematology, 2021, 96 (8), pp.1008-1016. ⟨10.1002/ajh.26189⟩
American Journal of Hematology, Wiley, 2021, 96 (8), pp.1008-1016. ⟨10.1002/ajh.26189⟩

No data; International audience; The role of iron in the formation and functioning of erythrocytes, and to a lesser degree of white blood cells, is well established, but the relationship between iron and platelets is less documented. Physiologically,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e46bbad0cf5a2b569a8867e7068c56bb
https://doi.org/10.1002/ajh.26189

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Hemochromatosis classification: update and recommendations by the BIOIRON Society

Autor: Pierre Brissot, Ioav Cabantchik, Fabiana Busti, Domenico Girelli, Martina U. Muckenthaler, Graça Porto

Publikováno v: Blood
Blood, 2022, 139 (20), pp.3018-3029. ⟨10.1182/blood.2021011338⟩
Blood, American Society of Hematology, 2021, ⟨10.1182/blood.2021011338⟩

Hemochromatosis (HC) is a genetically heterogeneous disorder in which uncontrolled intestinal iron absorption may lead to progressive iron overload (IO) responsible for disabling and life-threatening complications such as arthritis, diabetes, heart f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::416d5dcdc653ae0cf8a7c0ae40fc56d9
https://hal.science/hal-03418911/document

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Haemochromatosis revisited

Autor: Aline Morgan Alvarenga, Pierre Brissot, Paulo Caleb Junior Lima Santos

Publikováno v: World journal of hepatology
World journal of hepatology, 2022, 14 (11), pp.1931-1939. ⟨10.4254/wjh.v14.i11.1931⟩

International audience; Haemochromatosis is a genetic disease caused by hepcidin deficiency, responsible for an increase in intestinal iron absorption. Haemochromatosis is associated with homozygosity for the HFE p.Cys282Tyr mutation. However, rare c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9edb9b11b78be390aa3b09f7b850832f
https://pubmed.ncbi.nlm.nih.gov/36483608

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Quality of Life Scores Remained Different among the Genotypic Groups of Patients with Suspected Hemochromatosis, Even after Treatment Period

Autor: Luis Alfredo Utria Acevedo, Aline Morgan Alvarenga, Paula Fernanda Silva Fonseca, Nathália Kozikas da Silva, Rodolfo Delfini Cançado, Flavio Augusto Naoum, Carla Luana Dinardo, Alexandre Costa Pereira, Pierre Brissot, Paulo Caleb Junior Lima Santos

Publikováno v: Genes
Genes, 2022, 13 (1), pp.118. ⟨10.3390/genes13010118⟩
Genes, Vol 13, Iss 118, p 118 (2022)
Genes; Volume 13; Issue 1; Pages: 118

Background: Hemochromatosis is a genetic condition of iron overload caused by deficiency of hepcidin. In a previous stage of this study, patients with suspected hemochromatosis had their quality of life (QL) measured. We observed that QL scores diffe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02abae0cd656846cfdc08d0a42e03e17
https://hal.science/hal-03555426/document

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Akademický článek

Iron as a Therapeutic Target in HFE-Related Hemochromatosis: Usual and Novel Aspects

Autor: Olivier Loréal, Thibault Cavey, François Robin, Moussa Kenawi, Pascal Guggenbuhl, Pierre Brissot

Publikováno v: Pharmaceuticals, Vol 11, Iss 4, p 131 (2018)

Genetic hemochromatosis is an iron overload disease that is mainly related to the C282Y mutation in the HFE gene. This gene controls the expression of hepcidin, a peptide secreted in plasma by the liver and regulates systemic iron distribution. Homoz

Externí odkaz: https://doaj.org/article/3d022d849a074cc19f272546e8aeb2e7

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Akademický článek

Management of liver complications in haemoglobinopathies

Autor: Pierre Brissot, Olivier Loreal

Publikováno v: Thalassemia Reports, Vol 4, Iss 3 (2014)

Liver complications in haemoglobinopathies (thalassaemia and sickle cell disease) are due to several factors, dominated (beside chronic viral infections, not considered here) by chronic iron overload, biliary obstruction and venous thrombosis. Wherea

Externí odkaz: https://doaj.org/article/679c76b64af34245a12a989872f3408d

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Too much iron: A masked foe for leukemias

Autor: Pierre Brissot, Delphine G. Bernard, Eolia Brissot, Marie-Bérengère Troadec, Olivier Loréal

Publikováno v: Blood Reviews
Blood Reviews, Elsevier, 2020, 39, pp.100617. ⟨10.1016/j.blre.2019.100617⟩
Blood Reviews, 2020, 39, pp.100617. ⟨10.1016/j.blre.2019.100617⟩

International audience; The role of iron in non-erythroid hematopoietic lineages and its implication in hemato-oncogenesis are still debated. Iron exerts an important role on hematopoietic stem cell transformation and on mature white blood cell diffe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c4effc8823f031404c908ba6b5f91ad
https://hal-univ-rennes1.archives-ouvertes.fr/hal-02472239

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