Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Pierpaolo Risiglione"'
Autor:
Xena Giada Pappalardo, Pierpaolo Risiglione, Federica Zinghirino, Angela Ostuni, Daniela Luciano, Faustino Bisaccia, Vito De Pinto, Francesca Guarino, Angela Messina
Publikováno v:
Biological Research, Vol 56, Iss 1, Pp 1-22 (2023)
Abstract Background Voltage-dependent anion selective channels (VDACs) are the most abundant mitochondrial outer membrane proteins, encoded in mammals by three genes, VDAC1, 2 and 3, mostly ubiquitously expressed. As 'mitochondrial gatekeepers', VDAC
Externí odkaz:
https://doaj.org/article/ce2f217ef2684bd2aafd02b78600f514
Autor:
Andrea Magrì, Cristiana Lucia Rita Lipari, Pierpaolo Risiglione, Stefania Zimbone, Francesca Guarino, Antonella Caccamo, Angela Messina
Publikováno v:
Cell Death and Disease, Vol 14, Iss 2, Pp 1-10 (2023)
Abstract Mitochondrial dysfunction and the loss of mitophagy, aimed at recycling irreversibly damaged organelles, contribute to the onset of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease affecting spinal cord motor neurons. I
Externí odkaz:
https://doaj.org/article/e7e702e2f40c438eb047d99399d3e8d6
Autor:
Pierpaolo Risiglione, Salvatore Antonio Maria Cubisino, Cristiana Lucia Rita Lipari, Vito De Pinto, Angela Messina, Andrea Magrì
Publikováno v:
Life, Vol 12, Iss 6, p 894 (2022)
α-synuclein (αSyn) is a small neuronal protein whose accumulation correlates with Parkinson’s disease. αSyn A53T mutant impairs mitochondrial functions by affecting substrate import within the organelle, activity of complex I and the maximal res
Externí odkaz:
https://doaj.org/article/58f40eaff6d54f82aee03de92913c823
Autor:
Andrea Magrì, Pierpaolo Risiglione, Antonella Caccamo, Beatrice Formicola, Marianna Flora Tomasello, Cristina Arrigoni, Stefania Zimbone, Francesca Guarino, Francesca Re, Angela Messina
Publikováno v:
Biomedicines, Vol 9, Iss 8, p 948 (2021)
Mutations in Cu/Zn Superoxide Dismutase (SOD1) gene represent one of the most common causes of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disorder that specifically affects motor neurons (MNs). The dismutase-active SOD1 G93A mutan
Externí odkaz:
https://doaj.org/article/cfcc818ebf574fc0873743fe267cd71b
Autor:
Pierpaolo Risiglione, Federica Zinghirino, Maria Carmela Di Rosa, Andrea Magrì, Angela Messina
Publikováno v:
Biomolecules, Vol 11, Iss 5, p 718 (2021)
Alpha-Synuclein (αSyn) is a protein whose function is still debated, as well as its role in modulation of mitochondrial function in both physiological and pathological conditions. Mitochondrial porins or Voltage-Dependent Anion Channel (VDAC) protei
Externí odkaz:
https://doaj.org/article/7d1dc67c8a564383b2b47ec476a385b7
Autor:
Xena Giada Pappalardo, Pierpaolo Risiglione, Federica Zinghirino, Angela Ostuni, Daniela Luciano, Faustino Bisaccia, Vito De Pinto, Francesca Guarino, Angela Messina
BackgroundVoltage-dependent anion selective channels (VDACs) are the most abundant mitochondrial outer membrane proteins, encoded in mammals by three genes,VDAC1,2and3, mostly ubiquitously expressed. As ‘mitochondrial gatekeepers’,VDACscontrol or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9891f3a916b09e73c560f85555ede57e
https://doi.org/10.1101/2023.01.20.524880
https://doi.org/10.1101/2023.01.20.524880
Autor:
Loredana Leggio, Francesca L'Episcopo, Andrea Magrì, María José Ulloa‐Navas, Greta Paternò, Silvia Vivarelli, Carlos A. P. Bastos, Cataldo Tirolo, Nunzio Testa, Salvatore Caniglia, Pierpaolo Risiglione, Fabrizio Pappalardo, Alessandro Serra, Patricia García‐Tárraga, Nuno Faria, Jonathan J. Powell, Luca Peruzzotti‐Jametti, Stefano Pluchino, José Manuel García‐Verdugo, Angela Messina, Bianca Marchetti, Nunzio Iraci
Publikováno v:
Advanced Healthcare Materials. 11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d225f2992e051a89c6d85c31430f5169
https://doi.org/10.1002/adhm.202270124
https://doi.org/10.1002/adhm.202270124
Autor:
Francesco Pappalardo, Ulloa-Navas Mj, Pierpaolo Risiglione, Stefano Pluchino, Francesca L'Episcopo, Greta Paternò, Nunzio Testa, Silvia Vivarelli, José Manuel García-Verdugo, Nunzio Iraci, Salvatore Caniglia, Loredana Leggio, Bianca Marchetti, Bastos Cap, Andrea Magrì, Luca Peruzzotti-Jametti, Angela Messina, Nuno Faria, Cataldo Tirolo
Extracellular vesicles (EVs) are emerging as powerful players in cell-to-cell communication both in health and diseased brain. In Parkinson’s disease (PD) – characterized by selective dopaminergic (DAergic) neuron death in ventral midbrain (VMB)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::511035c54585f66adfb1333cad585ef2
https://doi.org/10.1101/2021.04.23.441135
https://doi.org/10.1101/2021.04.23.441135
Autor:
Simona Reina, Angela Messina, Greta Paternò, Salvatore Antonio Maria Cubisino, Andrea Magrì, Nunzio Iraci, Bianca Marchetti, Pierpaolo Risiglione, Loredana Leggio
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 21
International Journal of Molecular Sciences, Vol 21, Iss 7809, p 7809 (2020)
Volume 21
Issue 21
International Journal of Molecular Sciences, Vol 21, Iss 7809, p 7809 (2020)
MPP+ is the active metabolite of MPTP, a molecule structurally similar to the herbicide Paraquat, known to injure the dopaminergic neurons of the nigrostriatal system in Parkinson&rsquo
s disease models. Within the cells, MPP+ accumulates in mit
s disease models. Within the cells, MPP+ accumulates in mit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2f7af170d227c4477ab3ddee94a27d3
http://europepmc.org/articles/PMC7659480
http://europepmc.org/articles/PMC7659480