Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Pierpaolo Ceci"'
Autor:
Francesco Marrocco, Elisabetta Falvo, Luciana Mosca, Giada Tisci, Alessandro Arcovito, Alice Reccagni, Cristina Limatola, Roberta Bernardini, Pierpaolo Ceci, Giuseppina D’Alessandro, Gianni Colotti
Publikováno v:
Cell Death and Disease, Vol 15, Iss 4, Pp 1-10 (2024)
Abstract Gliomas are among the most fatal tumors, and the available therapeutic options are very limited. Additionally, the blood-brain barrier (BBB) prevents most drugs from entering the brain. We designed and produced a ferritin-based stimuli-sensi
Externí odkaz:
https://doaj.org/article/6e3bf7316b2d4140a4a9dc60640a5167
Autor:
Giulio Fracasso, Elisabetta Falvo, Giada Tisci, Gianluca Sala, Gianni Colotti, Sara Cingarlini, Claudia Tito, Sandra Bibbo, Cristina Frusteri, Elisa Tremante, Elena Giordani, Patrizio Giacomini, Pierpaolo Ceci
Publikováno v:
Heliyon, Vol 9, Iss 10, Pp e20770- (2023)
Background: Cancer is still among the leading causes of death all over the world. Improving chemotherapy and minimizing associated toxicities are major unmet medical needs. Recently, we provided a preliminary preclinical evaluation of a human ferriti
Externí odkaz:
https://doaj.org/article/25b7226ed4974a9dbaadcf2acec008ae
Autor:
Elisabetta Falvo, Verena Damiani, Giamaica Conti, Federico Boschi, Katia Messana, Patrizio Giacomini, Michele Milella, Vincenzo De Laurenzi, Veronica Morea, Gianluca Sala, Giulio Fracasso, Pierpaolo Ceci
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-14 (2021)
Abstract Background Ferritin receptor (CD71) is an example of a very attractive cancer target, since it is highly expressed in virtually all tumor types, including metastatic loci. However, this target can be considered to be inaccessible to conventi
Externí odkaz:
https://doaj.org/article/9e69bc049eb0484e9987bd48a32027e6
Autor:
Linda Celeste Montemiglio, Claudia Testi, Pierpaolo Ceci, Elisabetta Falvo, Martina Pitea, Carmelinda Savino, Alessandro Arcovito, Giovanna Peruzzi, Paola Baiocco, Filippo Mancia, Alberto Boffi, Amédée des Georges, Beatrice Vallone
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
The human transferrin receptor 1 (CD71) is a transmembrane protein responsible for iron uptake. Here the authors present the 3.9 Å resolution cryo-EM structure of the CD71 ectodomain-human ferritin (H-Ft) complex and find that H-Ft binds a CD71 regi
Externí odkaz:
https://doaj.org/article/61472d52cca641faa05071392f71cf5c
Autor:
Rossella Loria, Claudia Giliberti, Angelico Bedini, Raffaele Palomba, Giulio Caracciolo, Pierpaolo Ceci, Elisabetta Falvo, Raffaella Marconi, Rita Falcioni, Gianluca Bossi, Lidia Strigari
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-11 (2019)
Abstract Background The possibility to combine Low Intensity UltraSound (LIUS) and Nanoparticles (NP) could represent a promising strategy for drugs delivery in tumors difficult to treat overcoming resistance to therapies. On one side the NP can carr
Externí odkaz:
https://doaj.org/article/cfebdae6934646d2bc7d0ec2ba8f95dd
Autor:
Giamaica Conti, Martina Pitea, Riccardo Ossanna, Roberta Opri, Giada Tisci, Elisabetta Falvo, Giulio Innamorati, Esther Ghanem, Andrea Sbarbati, Pierpaolo Ceci, Giulio Fracasso
Publikováno v:
Biomedicines, Vol 9, Iss 11, p 1622 (2021)
Pancreatic cancer (PC) represents an intriguing topic for researchers. To date, the prognosis of metastasized PC is poor with just 7% of patients exceeding a five-year survival period. Thus, molecular modifications of existing drugs should be develop
Externí odkaz:
https://doaj.org/article/39a8cae188c14ca3b763e71c4222e23c
Autor:
Elisabetta Falvo, Alessandro Arcovito, Giamaica Conti, Giuseppe Cipolla, Martina Pitea, Veronica Morea, Verena Damiani, Gianluca Sala, Giulio Fracasso, Pierpaolo Ceci
Publikováno v:
Pharmaceutics, Vol 12, Iss 10, p 992 (2020)
Gastrointestinal tumors, including pancreatic and colorectal cancers, represent one of the greatest public health issues worldwide, leading to a million global deaths. Recent research demonstrated that the human heavy chain ferritin (HFt) can encapsu
Externí odkaz:
https://doaj.org/article/28907bf696084f669accf6d1c2db09e2
Autor:
Luciana Mosca, Elisabetta Falvo, Pierpaolo Ceci, Elena Poser, Ilaria Genovese, Giulia Guarguaglini, Gianni Colotti
Publikováno v:
Applied Sciences, Vol 7, Iss 1, p 101 (2017)
The ability of ferritin to bind and deliver metals and metal-based drugs to human neuroblastoma SH-SY5Y cells was studied. We used heavy chain (H) ferritin-based metal-containing nanocarriers to test whether these constructs, which are able to cross
Externí odkaz:
https://doaj.org/article/c73df262e3564987a80a026e246636c5
Autor:
Pierpaolo Ceci, Francesco Pineider, Elvira Fantechi, Claudia Innocenti, Claudio Sangregorio, Elisabetta Falvo, Anna M. Ferretti
Publikováno v:
Journal of nanoscience and nanotechnology
19 (2019): 4964–4973. doi:10.1166/jnn.2019.16801
info:cnr-pdr/source/autori:Fantechi, Elvira; Innocenti, Claudia; Ferretti, Anna Maria; Falvo, Elisabetta; Ceci, Pierpaolo; Pineider, Francesco; Sangregorio, Claudio/titolo:Increasing the Magnetic Anisotropy of a Natural System: Co-Doped Magnetite Mineralized in Ferritin Shells/doi:10.1166%2Fjnn.2019.16801/rivista:Journal of nanoscience and nanotechnology (Print)/anno:2019/pagina_da:4964/pagina_a:4973/intervallo_pagine:4964–4973/volume:19
19 (2019): 4964–4973. doi:10.1166/jnn.2019.16801
info:cnr-pdr/source/autori:Fantechi, Elvira; Innocenti, Claudia; Ferretti, Anna Maria; Falvo, Elisabetta; Ceci, Pierpaolo; Pineider, Francesco; Sangregorio, Claudio/titolo:Increasing the Magnetic Anisotropy of a Natural System: Co-Doped Magnetite Mineralized in Ferritin Shells/doi:10.1166%2Fjnn.2019.16801/rivista:Journal of nanoscience and nanotechnology (Print)/anno:2019/pagina_da:4964/pagina_a:4973/intervallo_pagine:4964–4973/volume:19
Iron oxide nanoparticles mineralized within the internal cavity of Ferritin protein cage are extremely appealing for the realization of multifunctional therapeutic and diagnostic agents for cancer treatment by drug delivery, magnetic fluid hypertherm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47afc3484c84506fa305f40d6314e73d
https://doi.org/10.1166/jnn.2019.16801
https://doi.org/10.1166/jnn.2019.16801
Autor:
Elisabetta Falvo, Giulio Caracciolo, Pierpaolo Ceci, Raffaella Marconi, Lidia Strigari, Rita Falcioni, Rossella Loria, Raffaele Palomba, Angelico Bedini, Claudia Giliberti, Gianluca Bossi
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-11 (2019)
Journal of experimental & clinical cancer research (Online) 38 (2019). doi:10.1186/s13046-018-1018-6
info:cnr-pdr/source/autori:Loria, Rossella; Giliberti, Claudia; Bedini, Angelico; Palomba, Raffaele; Caracciolo, Giulio; Ceci, Pierpaolo; Falvo, Elisabetta; Marconi, Raffaella; Falcioni, Rita; Bossi, Gianluca; Strigari, Lidia/titolo:Very low intensity ultrasounds as a new strategy to improve selective delivery of nanoparticles-complexes in cancer cells/doi:10.1186%2Fs13046-018-1018-6/rivista:Journal of experimental & clinical cancer research (Online)/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume:38
Journal of Experimental & Clinical Cancer Research : CR
Journal of experimental & clinical cancer research (Online) 38 (2019). doi:10.1186/s13046-018-1018-6
info:cnr-pdr/source/autori:Loria, Rossella; Giliberti, Claudia; Bedini, Angelico; Palomba, Raffaele; Caracciolo, Giulio; Ceci, Pierpaolo; Falvo, Elisabetta; Marconi, Raffaella; Falcioni, Rita; Bossi, Gianluca; Strigari, Lidia/titolo:Very low intensity ultrasounds as a new strategy to improve selective delivery of nanoparticles-complexes in cancer cells/doi:10.1186%2Fs13046-018-1018-6/rivista:Journal of experimental & clinical cancer research (Online)/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume:38
Journal of Experimental & Clinical Cancer Research : CR
Background The possibility to combine Low Intensity UltraSound (LIUS) and Nanoparticles (NP) could represent a promising strategy for drugs delivery in tumors difficult to treat overcoming resistance to therapies. On one side the NP can carry drugs t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c40473e9a1ef2c3b59261b57703d55d3
http://link.springer.com/article/10.1186/s13046-018-1018-6
http://link.springer.com/article/10.1186/s13046-018-1018-6