Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Piero Pingitore"'
Autor:
Daniel Lindén, Andrea Ahnmark, Piero Pingitore, Ester Ciociola, Ingela Ahlstedt, Anne-Christine Andréasson, Kavitha Sasidharan, Katja Madeyski-Bengtson, Magdalena Zurek, Rosellina M. Mancina, Anna Lindblom, Mikael Bjursell, Gerhard Böttcher, Marcus Ståhlman, Mohammad Bohlooly-Y, William G. Haynes, Björn Carlsson, Mark Graham, Richard Lee, Sue Murray, Luca Valenti, Sanjay Bhanot, Peter Åkerblad, Stefano Romeo
Publikováno v:
Molecular Metabolism, Vol 22, Iss , Pp 49-61 (2019)
Objective: Nonalcoholic fatty liver disease (NAFLD) is becoming a leading cause of advanced chronic liver disease. The progression of NAFLD, including nonalcoholic steatohepatitis (NASH), has a strong genetic component, and the most robust contributo
Externí odkaz:
https://doaj.org/article/f77b71978d104e8aa87a52faaeaa4522
Autor:
Brian E. Schwartz, Vaishnavi Rajagopal, Cynthia Smith, Evan Cohick, Gavin Whissell, Mario Gamboa, Rutuja Pai, Alla Sigova, Iris Grossman, David Bumcrot, Kavitha Sasidharan, Stefano Romeo, Alfica Sehgal, Piero Pingitore
Publikováno v:
Cells, Vol 9, Iss 10, p 2247 (2020)
Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are emerging worldwide epidemics, projected to become the leading cause of liver transplants. The strongest genetic risk factor for NAFLD/NASH susceptibility and progr
Externí odkaz:
https://doaj.org/article/b9527f2c6bfc417cb689ed58bec3220f
Autor:
Ulrika Lind, Michael Järvå, Magnus Alm Rosenblad, Piero Pingitore, Emil Karlsson, Anna-Lisa Wrange, Emelie Kamdal, Kristina Sundell, Carl André, Per R Jonsson, Jon Havenhand, Leif A Eriksson, Kristina Hedfalk, Anders Blomberg
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0181192 (2017)
Barnacles are sessile macro-invertebrates, found along rocky shores in coastal areas worldwide. The euryhaline bay barnacle Balanus improvisus (Darwin, 1854) (= Amphibalanus improvisus) can tolerate a wide range of salinities, but the molecular mecha
Externí odkaz:
https://doaj.org/article/828da2e6bbd944f6aa3ebfe8f439f78a
Publikováno v:
Annals of Hepatology, Vol 17, Iss 2, Pp 180-181 (2018)
Externí odkaz:
https://doaj.org/article/14607bf4564d4deea04934797b8e2998
Autor:
Oveis Jamialahmadi, Annika Janefeldt, Carl Whatling, Luca Valenti, Mikael Kozyra, Kajsa P. Kanebratt, Tommy B. Andersson, Arturo Pujia, Paola Dongiovanni, Andrea Caddeo, Rosellina Margherita Mancina, Sebastian Prill, Magnus Ingelman-Sundberg, Stefano Romeo, Raffaela Rametta, Daniel Lindén, Guido Baselli, Piero Pingitore
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
There is a high unmet need for developing treatments for nonalcoholic fatty liver disease (NAFLD), for which there are no approved drugs today. Here, we used a human in vitro disease model to understand mechanisms linked to genetic risk variants asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6953b6f68cdc7dba1a2498c7059111ea
http://link.springer.com/article/10.1038/s41598-019-47737-w
http://link.springer.com/article/10.1038/s41598-019-47737-w
Autor:
Piero Pingitore, Stefano Romeo
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1864:900-906
The human patatin-like phospholipase domain-containing 3 (PNPLA3) gene encodes for a protein of 481 amino-acids. The variant rs738409 is a cytosine to guanine substitution, encoding for the isoleucine to methionine substitution at position 148 (I148M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48329db9a2d1d42b2919ccd80ec1c06f
https://doi.org/10.1016/j.bbalip.2018.06.018
https://doi.org/10.1016/j.bbalip.2018.06.018
Publikováno v:
Biochimica et biophysica acta. Molecular and cell biology of lipids. 1866(5)
Human membrane bound O-acyltransferase domain-containing 7 (MBOAT7), also known as lysophosphatidylinositol acyltransferase 1 (LPIAT1), is an enzyme involved in the acyl-chain remodeling of phospholipids via the Lands' cycle. The MBOAT7 rs641738 vari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40eae56ab8eed23ba4a68b96c9d912cb
https://pubmed.ncbi.nlm.nih.gov/33513444
https://pubmed.ncbi.nlm.nih.gov/33513444
Autor:
Andrea Caddeo, Piero Pingitore, O. Jamialahmadi, Stefano Romeo, Kavitha Sasidharan, F. Malvestiti, Guido Baselli, Luca Valenti
Publikováno v:
Atherosclerosis. 331:e143
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71f1c2dcc19d4cfb1de32c8c31531c46
https://doi.org/10.1016/j.atherosclerosis.2021.06.426
https://doi.org/10.1016/j.atherosclerosis.2021.06.426
Autor:
Alice Emma Taliento, Marica Meroni, Paola Dongiovanni, Rosellina Margherita Mancina, Stefano Romeo, Daniele Prati, Marco Maggioni, Anna Ludovica Fracanzani, Giorgio Rossi, Luca Valenti, Piero Pingitore, Guido Baselli, Serena Pelusi, Sara Badiali, Tiziana Montalcini, Raffaela Rametta, Samantha Maurotti
Publikováno v:
Gut
ObjectiveEfforts to manage non-alcoholic fatty liver disease (NAFLD) are limited by the incomplete understanding of the pathogenic mechanisms and the absence of accurate non-invasive biomarkers. The aim of this study was to identify novel NAFLD thera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::242293d03dade29f6f5a650c3d9bfdbc
https://pubmed.ncbi.nlm.nih.gov/32001554
https://pubmed.ncbi.nlm.nih.gov/32001554
Autor:
Matias Ekstrand, Piero Pingitore, Stefano Romeo, Daniel Lindén, Sebastian Prill, Kavitha Sasidharan
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 20, Iss 7, p 1629 (2019)
Volume 20
Issue 7
International Journal of Molecular Sciences, Vol 20, Iss 7, p 1629 (2019)
Volume 20
Issue 7
Non-alcoholic fatty liver disease (NAFLD) is the most common liver disorder in western countries. Despite the high prevalence of NAFLD, the underlying biology of the disease progression is not clear, and there are no approved drugs to treat non-alcoh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40810d15b16173cb0ce0c2a58f3030a4
https://pubmed.ncbi.nlm.nih.gov/30986904
https://pubmed.ncbi.nlm.nih.gov/30986904