Výsledky vyhledávání - "Piero Liberti"

Schistosoma mansoni: Lack of correlation between praziquantel-induced intra-worm calcium influx and parasite death

Autor: Piero Liberti, Tiziana Orsini, Cristiana Valle, Livia Pica-Mattoccia, Annalisa Basso, Sonia Nobre-Santana, Ana-Luiza Marcatto-Maggi, Alfredo Festucci, Alessandra Guidi, Donato Cioli, Anna-Rita Troiani

Publikováno v: Experimental parasitology 119 (2008): 332–335. doi:10.1016/j.exppara.2008.03.012
info:cnr-pdr/source/autori:Pica-Mattoccia L, Orsini T, Basso A, Festucci A, Liberti P, Guidi A, Marcatto-Maggi AL, Nobre-Santana S, Troiani AR, Cioli D, Valle C./titolo:Schistosoma mansoni: lack of correlation between praziquantel-induced intra-worm calcium influx and parasite death./doi:10.1016%2Fj.exppara.2008.03.012/rivista:Experimental parasitology/anno:2008/pagina_da:332/pagina_a:335/intervallo_pagine:332–335/volume:119

The schistosomicidal activity of praziquantel (PZQ) is accompanied by a large influx of calcium into the worms, suggesting that this phenomenon could be the source of the observed muscular contraction, surface disruption and eventual death of the par

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37504f53b1b8269b35f7c9b868a385fa
https://doi.org/10.1016/j.exppara.2008.03.012

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Cytochalasin D abolishes the schistosomicidal activity of praziquantel

Autor: Anna Rita Troiani, Donato Cioli, Livia Pica-Mattoccia, Alfredo Festucci, Piero Liberti, Cristiana Valle, Annalisa Basso, Fabio Vigorosi

Publikováno v: Experimental parasitology 115 (2007): 344–351. doi:10.1016/j.exppara.2006.09.017
info:cnr-pdr/source/autori:Pica-Mattoccia L., Valle C., Basso A., Troiani A.R., Vigorosi F., Liberti P., Festucci A. and Cioli D./titolo:Cytochalasin D abolishes the schistosomicidal activity of praziquantel./doi:10.1016%2Fj.exppara.2006.09.017/rivista:Experimental parasitology/anno:2007/pagina_da:344/pagina_a:351/intervallo_pagine:344–351/volume:115

To test the hypothesis that calcium channels of schistosomes are the targets for the action of praziquantel, we subjected schistosomes in vitro to pharmacological agents capable of interfering with the functioning of calcium channels. After 1-h expos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79e2df21234c8812756d734393bc4da2
https://doi.org/10.1016/j.exppara.2006.09.017

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Sequence and level of endogenous expression of calcium channel β subunits in Schistosoma mansoni displaying different susceptibilities to praziquantel

Autor: Anna Rita Troiani, Donato Cioli, Livia Pica-Mattoccia, Adrian J. Wolstenholme, Michael J. Doenhoff, Piero Liberti, Katherine Francklow, Alfredo Festucci, Cristiana Valle

Publikováno v: Molecular and Biochemical Parasitology. 130:111-115

Kohn et al. [J. Biol. Chem. 276 (2001) 36873] demonstrated that cells expressing the structurally unusual schistosome beta subunit SmCavbeta1 in their voltage-operated calcium channels, exhibit an increased current amplitude in the presence of praziq

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc49d3b8c3b0fc958350a82dd941e886
https://doi.org/10.1016/s0166-6851(03)00171-3

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Stage-specific Expression of a Schistosoma mansoniPolypeptide Similar to the Vertebrate Regulatory Protein Stathmin

Autor: Paola Macrı̀, Anna Calogero, Piero Liberti, Donato Cioli, Alfredo Festucci, Barbara Mecozzi, Cristiana Valle

Publikováno v: Journal of Biological Chemistry. 274:33869-33874

The ubiquitous vertebrate protein stathmin is expressed and phosphorylated in response to a variety of external and internal signals. Stathmin, in turn, controls cell growth and differentiation through its capacity to regulate microtubule assembly dy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c216cb41b8ab16a5da6fc8cf079619fb
https://doi.org/10.1074/jbc.274.48.33869

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Genetic analysis of decreased praziquantel sensitivity in a laboratory strain of Schistosoma mansoni

Autor: Livia Pica-Mattoccia, Cristiana Valle, Anna-Rita Troiani, Michael J. Doenhoff, Piero Liberti, Annalisa Basso, Donato Cioli, Alessandra Guidi, Alfredo Festucci

Publikováno v: Acta tropica 111 (2009): 82–85. doi:10.1016/j.actatropica.2009.01.012
info:cnr-pdr/source/autori:Pica-Mattoccia L, Doenhoff MJ, Valle C, Basso A, Troiani AR, Liberti P, Festucci A, Guidi A, Cioli D/titolo:Genetic analysis of decreased praziquantel sensitivity in a laboratory strain of Schistosoma mansoni/doi:10.1016%2Fj.actatropica.2009.01.012/rivista:Acta tropica/anno:2009/pagina_da:82/pagina_a:85/intervallo_pagine:82–85/volume:111

A laboratory strain of Schistosoma mansoni subjected to repeated in vivo praziquantel (PZQ) treatments for several generations has been previously found to have lesser sensitivity to the drug than the original unselected strain. In this study we have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e83cc659917eef774243397b1deb7194
https://pubmed.ncbi.nlm.nih.gov/19426668

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Schistosoma mansoni fatty acid binding protein: specificity and functional control as revealed by crystallographic structure

Autor: Kenneth A. Johnson, Donato Cioli, Piero Liberti, Adriana E. Miele, Francesco Angelucci, Maurizio Brunori, Fabio Vigorosi, Paola Baiocco, Mo Quen Klinkert, Andrea Bellelli, Anna Rita Troiani, Cristiana Valle

Publikováno v: Biochemistry (Easton) 43 (2004): 13000–13011. doi:10.1021/bi048505f
info:cnr-pdr/source/autori:Angelucci F, Johnson KA, Baiocco P, Miele AE, Brunori M, Valle C, Vigorosi F, Troiani AR, Liberti P, Cioli D, Klinkert MQ, Bellelli A./titolo:Schistosoma mansoni fatty acid binding protein: specificity and functional control as revealed by crystallographic structure./doi:10.1021%2Fbi048505f/rivista:Biochemistry (Easton)/anno:2004/pagina_da:13000/pagina_a:13011/intervallo_pagine:13000–13011/volume:43

Schistosoma mansoni fatty acid binding protein (Sm14) was crystallized with bound oleic acid (OLA) and arachidonic acid (ACD), and their structures were solved at 1.85 and 2.4 A resolution, respectively. Sm14 is a vaccine target for schistosomiasis,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00b47bd4240805d6430d7c99c3981e37
https://pubmed.ncbi.nlm.nih.gov/15476393

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Schistosoma japonicum: modern tools for an ancient disease

Autor: Piero Liberti, Donato Cioli

Publikováno v: The Lancet. 363:180-181

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01ebdb002490e2d8ebf535769aa95678
https://doi.org/10.1016/s0140-6736(03)15366-4

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Kinetics of DNA and histone messenger RNA synthesis in CV-1 monkey kidney cells infected with simian virus 40

Autor: Piero Liberti, Cesare Vesco, Lia Fischer-Fantuzzi

Publikováno v: Journal of molecular biology. 105(2)

Histone messenger RNA has been identified in CV-1 monkey kidney cells and its synthesis during the simian virus 40 (SV40) productive cycle has been correlated with the synthesis of cellular DNA and viral DNA. In cultures of CV-1 cells that have reach

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8a809830362d781ec6c9315ad2a1eb5
https://pubmed.ncbi.nlm.nih.gov/184287

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