Zobrazeno 1 - 10
of 405
pro vyhledávání: '"Piero Anversa"'
Autor:
Ramaswamy Kannappan, Alex Matsuda, João Ferreira-Martins, Eric Zhang, Giorgia Palano, Anna Czarna, Mauricio Castro Cabral-Da-Silva, Adriana Bastos-Carvalho, Fumihiro Sanada, Noriko Ide, Marcello Rota, Maria A. Blasco, Manuel Serrano, Piero Anversa, Annarosa Leri
Publikováno v:
EBioMedicine, Vol 16, Iss C, Pp 224-237 (2017)
p53 is an important modulator of stem cell fate, but its role in cardiac progenitor cells (CPCs) is unknown. Here, we tested the effects of a single extra-copy of p53 on the function of CPCs in the presence of oxidative stress mediated by doxorubicin
Externí odkaz:
https://doaj.org/article/7447d72e79c84aae90e8708bafb7ff25
Publikováno v:
Stem Cell Research, Vol 13, Iss 3, Pp 631-646 (2014)
The critical role that stem cell niches have in cardiac homeostasis and myocardial repair following injury is the focus of this review. Cardiac niches represent specialized microdomains where the quiescent and activated state of resident stem cells i
Externí odkaz:
https://doaj.org/article/ab9a15aac2dd4fb1b177de326ba75300
Autor:
Marianna Meo, Olivier Meste, Sergio Signore, Andrea Sorrentino, Antonio Cannata, Yu Zhou, Alex Matsuda, Marco Luciani, Ramaswamy Kannappan, Polina Goichberg, Annarosa Leri, Piero Anversa, Marcello Rota
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 2 (2016)
BackgroundDiabetes is associated with prolongation of the QT interval of the electrocardiogram and enhanced dispersion of ventricular repolarization, factors that, together with atherosclerosis and myocardial ischemia, may promote the occurrence of e
Externí odkaz:
https://doaj.org/article/645bd8cfb6bb49b49d69c158b3b48c2a
Publikováno v:
Arquivos Brasileiros de Cardiologia, Vol 87, Iss 2, Pp 71-72 (2006)
Externí odkaz:
https://doaj.org/article/8013117c961e489cb23680d32e87b8da
Publikováno v:
CellR4 Repair Replace Regen Reprogram
Autor:
Keerat Kaur, Piero Anversa, Polina Goichberg, Leonard M. Eisenberg, Khaled Qanud, John G. Edwards, Giulia Borghetti, Annarosa Leri, Alejandro Andrade-Vicenty, Carol A. Eisenberg, Marcello Rota, Mriganka Nerkar, Andrea Sorrentino, Sergio Signore, Thomas H. Hintze, Dong Sun, Jason T. Jacobson
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 314:H68-H81
Notch receptor signaling is active during cardiac development and silenced in myocytes after birth. Conversely, outward K+Kv currents progressively appear in postnatal myocytes leading to shortening of the action potential (AP) and acquisition of the
Autor:
Filippo Crea, Ramaswamy Kannappan, Junghyun Kim, Annarosa Leri, Alex Matsuda, Toru Hosoda, Sergio Signore, Fumihiro Sanada, Andrea Sorrentino, Marcello Rota, Piero Anversa, Antonio Cannatà, Anna Czarna, João D. Pereira
Publikováno v:
npj Regenerative Medicine, Vol 2, Iss 1, Pp 1-15 (2017)
NPJ Regenerative Medicine
NPJ Regenerative Medicine
The plasticity of c-kit-positive bone marrow cells (c-kit-BMCs) in tissues different from their organ of origin remains unclear. We tested the hypothesis that c-kit-BMCs are functionally heterogeneous and only a subgroup of these cells possesses card
Autor:
Piero Anversa, Marcello Rota, Khaled Qanud, Giulia Borghetti, Antonio Cannatà, Jason T. Jacobson, Yu Zhou, Polina Goichberg, Marianna Meo, Annarosa Leri, Sergio Signore, Thomas H. Hintze, Andrea Sorrentino
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 312:H150-H161
Diabetes and other metabolic conditions characterized by elevated blood glucose constitute important risk factors for cardiovascular disease. Hyperglycemia targets myocardial cells rendering ineffective mechanical properties of the heart, but cellula
Autor:
David A. D'Alessandro, Jan Kajstura, Domenico D'Amario, Piero Anversa, Claudia Fiorini, Hanqiao Zheng, Toru Hosoda, Sergio Ottolenghi, F. Del Monte, Polina Goichberg, João Ferreira-Martins, Robert E. Michler, Yingnan Bai, Sergio Signore, Marcello Rota, Annarosa Leri
Publikováno v:
Circulation Research. 124
Autor:
David A. D'Alessandro, Marco Luciani, Thomas H. Hintze, Giulia Borghetti, Ewa Wybieralska, Edward G. Barrett, Khaled Qanud, Maria Cimini, Christopher Royer, Polina Goichberg, Alex Matsuda, Elizabeth Kertowidjojo, Eric Zhang, Yu Zhou, Andrea Sorrentino, Ramaswamy Kannappan, Piero Anversa, Antonio Cannatà, Andrew Webster, Annarosa Leri, Marianna Meo, Oriyanhan Wunimenghe, Marcello Rota, Sergio Signore, Robert E. Michler
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 310:H873-H890
Studies of myocardial aging are complex and the mechanisms involved in the deterioration of ventricular performance and decreased functional reserve of the old heart remain to be properly defined. We have studied a colony of beagle dogs from 3 to 14