Zobrazeno 1 - 10
of 609
pro vyhledávání: '"Pierluigi Porcu"'
Autor:
Daniel Joffe, BS, Thomas Z. Rohan, BS, Jenna Mandel, BS, Jayson Suriano, BA, Lauren Banner, BS, Alexander Valiga, MD, Pierluigi Porcu, MD, Jerald Z. Gong, MD, Jason B. Lee, MD, Onder Alpdogan, MD, Neda Nikbakht, MD, PhD
Publikováno v:
JAAD Case Reports, Vol 49, Iss , Pp 51-54 (2024)
Externí odkaz:
https://doaj.org/article/67d7f782c7e74d26866eaa0c598deea1
Autor:
Nitin Chakravarti, Amy Boles, Rachel Burzinski, Paola Sindaco, Colleen Isabelle, Kathleen McConnell, Anjali Mishra, Pierluigi Porcu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Dysregulated nuclear-cytoplasmic trafficking has been shown to play a role in oncogenesis in several types of solid tumors and hematological malignancies. Exportin 1 (XPO1) is responsible for the nuclear export of several proteins and RNA sp
Externí odkaz:
https://doaj.org/article/248bba16e59443cc88b7d30a66cba310
Autor:
Clare M. Adams, Amanda McBride, Peter Michener, Irina Shkundina, Ramkrishna Mitra, Hyun Hwan An, Pierluigi Porcu, Christine M. Eischen
Publikováno v:
Cancers, Vol 16, Iss 11, p 2130 (2024)
Clinical trials with single-agent venetoclax/ABT-199 (anti-apoptotic BCL2 inhibitor) revealed that diffuse large B-cell lymphoma (DLBCL) is not solely dependent on BCL2 for survival. Gaining insight into pathways/proteins that increase venetoclax sen
Externí odkaz:
https://doaj.org/article/56d267c96f724961b0758b4f03316021
Autor:
Safiyyah Bhatti, Daniel Joffe, Lauren Banner, Sahithi Talasila, Jenna Mandel, Jason Lee, Pierluigi Porcu, Neda Nikbakht
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Cutaneous adverse events of both topical and systemic drugs in patients with mycosis fungoides (MF) present a diagnostic challenge as it is often difficult to distinguish drug associated rash from disease progression in the skin. Mogamulizumab and me
Externí odkaz:
https://doaj.org/article/21b65495e0024c6891d8f2b0112e3f47
Autor:
Laura Gleason, Volkan Tekmen, Alexa Cohen, Safiyyah Bhatti, Burcu Beksac, Jisun Cha, Pierluigi Porcu, Neda Nikbakht
Publikováno v:
International Journal of Dermatology and Venerology, Vol 6, Iss 2, Pp 107-109 (2023)
Introduction:. Mastocytosis, a clonal proliferation of mast cells commonly involving the skin and bone marrow, has a varied clinical presentation ranging from cutaneous lesions to systemic disease. Cutaneous mastocytosis is managed symptomatically, b
Externí odkaz:
https://doaj.org/article/cb57703ca0454530942a40e345907ff0
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Nearly a billion people worldwide are infected with the hepatitis B Virus (HBV) and about a third of them have chronic infection. HBV is an important cause of morbidity and mortality, including acute and chronic hepatitis and hepatocellular carcinoma
Externí odkaz:
https://doaj.org/article/2c3aed3440c3451186f07bc1a171ca7c
Autor:
Laura Gleason, Daniel Joffe, Safiyyah Bhatti, Alexa Cohen, Lauren Banner, Emily Correia, Onder Alpdogan, Pierluigi Porcu, Neda Nikbakht
Publikováno v:
Case Reports in Oncology, Vol 15, Iss 3, Pp 1088-1094 (2022)
Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a rare subtype of cutaneous T-cell lymphoma that usually presents with tender subcutaneous nodules on the trunk and extremities. Immunosuppressive therapy is considered first-line treatment fo
Externí odkaz:
https://doaj.org/article/64fee2230e8644f1afdd9432c91a0d71
Autor:
Paola Sindaco, Hritisha Pandey, Colleen Isabelle, Nitin Chakravarti, Jonathan Edward Brammer, Pierluigi Porcu, Anjali Mishra
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Cytokines are a vital component of the immune system that controls the activation and growth of blood cells. However, chronic overexpression of cytokines can trigger cellular events leading to malignant transformation. The cytokine interleukin-15 (IL
Externí odkaz:
https://doaj.org/article/be22487a35cf4f4babc0ec73a6e1bf00
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
IntroductionThe increased incidence of cutaneous melanoma (CM) and Merkel cell carcinoma (MCC) in patients with hematologic malignancies (HM) is well established. While the risk of CM has been assessed in some subtypes of HM including cutaneous T-cel
Externí odkaz:
https://doaj.org/article/4f9f2b6ecfe444b0993eda58780a4848
Publikováno v:
Frontiers in Oncology, Vol 12 (2023)
Externí odkaz:
https://doaj.org/article/dbc1253fb28448a29cb0e4c0f4883294