Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Pierluigi Patriarca"'
Publikováno v:
Blood. 90:4126-4134
Hereditary myeloperoxidase (MPO) deficiency is a neutrophil disorder characterized by the lack of peroxidase activity. Cytochemical, biochemical, spectroscopic, immunocytochemical, and genetic studies were carried out on a 5-year-old MPO-deficient su
Publikováno v:
The Journal of Cell Biology
Chloride ion efflux is an early event occurring after exposure of neutrophilic polymorphonuclear leukocytes (PMN) in suspension to several agonists, including cytokines such as tumor necrosis factor-alpha (TNF) and granulocyte/macrophage-colony stimu
Publikováno v:
European Journal of Immunology. 25:1366-1373
Inhibition of growth or eradication of experimentally induced tumors has been shown to be accompanied by infiltration of eosinophils and macrophages into the tumor mass. Since macrophages are important mediators of host antitumor activity, the possib
Publikováno v:
Europe PubMed Central
Generation and release into the culture medium of a cytolytic toxin by Gardnerella vaginalis has been demonstrated. Addition of starch and of the nonionic detergent Tween 80 to the culture medium was essential to recover cytolytic activity. A protein
Microbicidal activity of neutrophils is usually measured by colony-counting techniques after cell lysis in distilled water. While studying the effect of the reduced nicotinamide adenine dinucleotide phosphate-oxidase inhibitor diphenyleneiodonium (DP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc64dad820190f3d090d3373fbb1e3c6
http://hdl.handle.net/11368/2743099
http://hdl.handle.net/11368/2743099
Autor:
Caterina, Marchetti, Pierluigi, Patriarca, G Pietro, Solero, Francisco E, Baralle, Maurizio, Romano
Publikováno v:
Japanese journal of infectious diseases. 57(5)
Hereditary myeloperoxidase (MPO) deficiency is the most common neutrophil biochemical defect characterized by the lack of peroxidase activity. In order to extend the epidemiological studies on hereditary MPO deficiency in Italy, approximately 40,000
Autor:
G. Pietro Solero, Caterina Marchetti, Francisco E. Baralle, Maurizio Romano, Pierluigi Patriarca
Publikováno v:
Human mutation. 23(5)
Hereditary myeloperoxidase (MPO) deficiency (MPOD) is the most common neutrophil biochemical defect, and is characterized by a lack of peroxidase activity. In order to extend the epidemiological studies on hereditary MPOD in Italy, a population scree
Publikováno v:
Cytometry. Part A : the journal of the International Society for Analytical Cytology. 58(2)
Background Distinguishing ingested particles from those attached to the cell surface is an essential requirement when performing quantitative studies of phagocytosis. In the present report, we describe a simple, sensitive and reliable flow cytofluoro
We previously showed that a metalloprotease and a serine protease mediate shedding of the TNF-R75 (75-kDa tumor necrosis factor receptor) in neutrophils. Here we show that elastase is the TNF-R75 solubilizing serine protease. Release of the TNF-R75 b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09b8274558d5c6d7b3bdac4b7552f84e
https://hdl.handle.net/11368/1693468
https://hdl.handle.net/11368/1693468
Autor:
Pierluigi Patriarca, Spiridione Garbisa, Renzo Menegazzi, Gianni Presani, Rita Cramer, Lavinia Albéri, Chiara Gasparini, Pietro Dri
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 165(4)
A down-modulation of both the 55-kDa (TNF-R55) and the 75-kDa (TNF-R75) TNF receptors is observed in neutrophils exposed to a variety of stimuli. Proteolytic cleavage of the extracellular region of both receptors (shedding) and, with TNF, internaliza