Zobrazeno 1 - 10 of 13 pro vyhledávání: '"Pierce Mullen"'
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Akademický článek
Dorsal root ganglia control nociceptive input to the central nervous system.
Autor: Han Hao, Rosmaliza Ramli, Caixue Wang, Chao Liu, Shihab Shah, Pierce Mullen, Varinder Lall, Frederick Jones, Jicheng Shao, Hailin Zhang, David B Jaffe, Nikita Gamper, Xiaona Du
Publikováno v: PLoS Biology, Vol 21, Iss 1, p e3001958 (2023)
Accumulating observations suggest that peripheral somatosensory ganglia may regulate nociceptive transmission, yet direct evidence is sparse. Here, in experiments on rats and mice, we show that the peripheral afferent nociceptive information undergoe
Externí odkaz: https://doaj.org/article/c537901d0434420a87a4bcff108dbe55
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2
Dorsal root ganglia control nociceptive input to the central nervous system
Autor: Han Hao, Rosmaliza Ramli, Caixue Wang, Chao Liu, Shihab Shah, Pierce Mullen, Varinder Lall, Frederick Jones, Jicheng Shao, Hailin Zhang, David B. Jaffe, Nikita Gamper, Xiaona Du
Publikováno v: PLoS biology. 21(1)
Accumulating observations suggest that peripheral somatosensory ganglia may regulate nociceptive transmission, yet direct evidence is sparse. Here, in experiments on rats and mice, we show that the peripheral afferent nociceptive information undergoe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ece162d47c8dbeb4e6d7f1d3acd4acad
https://pubmed.ncbi.nlm.nih.gov/36603052
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3
Kv3 Channels Contribute to the Excitability of Subpopulations of Spinal Cord Neurons in Lamina VII
Autor: Susan A. Deuchars, Jim Deuchars, Nadia Pilati, Pierce Mullen, Charles H. Large
Publikováno v: eNeuro. 9(1)
Autonomic parasympathetic preganglionic neurons (PGN) drive contraction of the bladder during micturition but remain quiescent during bladder filling. This quiescence is postulated to be due to recurrent inhibition of PGN by fast-firing adjoining int
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c68c484358bedcab27e815a783a962d
https://pubmed.ncbi.nlm.nih.gov/35058310
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4
Dorsal root ganglia control nociceptive input to the central nervous system
Autor: Ramli R, Caiyan Wang, Shao J, Pierce Mullen, Nikita Gamper, Han H, Hailin Zhang, Shihab Shah, Liu C, Frederick Jones, Lall, Xiaona Du, David B. Jaffe
Accumulating observations suggest that peripheral somatosensory ganglia may regulate pain transmission, yet direct evidence is sparse. Here we show that the peripheral afferent nociceptive information undergoes dynamic filtering within dorsal root ga
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ee2b4fc56d3946dadb5f0b7ed0f628f5
https://doi.org/10.1101/2021.07.14.452325
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6
Local Ca2+ signals couple activation of TRPV1 and ANO1 sensory ion channels
Autor: Pierce Mullen, Viktor Lukacs, Shihab Shah, Stephen Milne, Nikita Gamper, Mark S. Shapiro, Chase M. Carver
Publikováno v: Sci Signal
ANO1 (TMEM16A) is a Ca(2+)-activated Cl(−) channel (CaCC) expressed in peripheral somatosensory neurons that are activated by painful (noxious) stimuli. These neurons also express the Ca(2+)-permeable channel and noxious heat sensor TRPV1, which ca
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a9894ab3f6938b5ccf2efcaf5d453cb
https://eprints.whiterose.ac.uk/159064/1/Shah_et_al_2020_accepted_version.pdf
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8
Vascular Kv7 channels control intracellular Ca2+ dynamics in smooth muscle
Autor: Yuan-Ming Tsai, Nikita Gamper, Karen E. Porter, Chris Peers, Frederick Jones, Pierce Mullen, Derek S. Steele
Publikováno v: Cell Calcium
Graphical abstract
Highlights • Inhibition of Kv7 channels induce Ca2+ signals through L- and T-type VGCCs in rat and human vascular smooth muscle cells. • Kv7.5 is functionally the most important subunit to mediate these effects. • Phosph
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf11c21f7e8cbff828e456b9086bd3fa
https://doi.org/10.1016/j.ceca.2020.102283
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