Multiscale analyses reveal native-like lamellar bone repair and near perfect bone-contact with porous strontium-loaded bioactive glass

Autor: Autefage, H, Allen, F, Tang, HM, Kallepitis, C, Gentleman, E, Reznikov, N, Nitiputri, K, Nommeots-Nomm, A, Young, G, Lee, PD, Pierce, BF, Wagermaier, W, Fratzl, P, Goodship, A, Jones, JR, Blunn, G, Stevens, M

The efficient healing of critical-sized bone defects using synthetic biomaterial-based strategies is promising but remains challenging as it requires the development of biomaterials that combine a 3D porous architecture and a robust biological activi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1032::ce69abeca01a8fbaa8c817a8fddcffcb
http://hdl.handle.net/10044/1/69687

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Autor: Drysdale M; GSK, Brentford, UK myriam.g.drysdale@gsk.com., Galimov ER; Imperial College Health Partners, London, UK., Yarwood MJ; Imperial College Health Partners, London, UK., Patel V; GSK, Brentford, UK., Levick B; Evidence & Access, OPEN Health Communications LLP, London, UK., Gibbons DC; GSK, Brentford, UK., Watkins JD; Imperial College Health Partners, London, UK., Young S; Imperial College Health Partners, London, UK., Pierce BF; Imperial College Health Partners, London, UK., Lloyd EJ; GSK, Brentford, UK., Kerr W; Global Medical Affairs, GSK, Brentford, Middlesex, UK., Birch HJ; GSK, Brentford, UK., Kamalati T; Imperial College Health Partners, London, UK., Brett SJ; Department of Surgery and Cancer, Imperial College London, London, UK.

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Multiscale analyses reveal native-like lamellar bone repair and near perfect bone-contact with porous strontium-loaded bioactive glass.

Autor: Autefage H; Department of Materials, Imperial College London, London, SW7 2AZ, United Kingdom; Department of Bioengineering, Imperial College London, London, SW7 2AZ, United Kingdom; Institute of Biomedical Engineering, Imperial College London, London, SW7 2AZ, United Kingdom., Allen F; Institute of Orthopaedics and Musculoskeletal Science, University College London, London, WC1E 6BT, United Kingdom., Tang HM; Department of Materials, Imperial College London, London, SW7 2AZ, United Kingdom., Kallepitis C; Department of Materials, Imperial College London, London, SW7 2AZ, United Kingdom; Department of Bioengineering, Imperial College London, London, SW7 2AZ, United Kingdom; Institute of Biomedical Engineering, Imperial College London, London, SW7 2AZ, United Kingdom., Gentleman E; Centre for Craniofacial and Regenerative Biology, King's College London, London, SE1 9RT, United Kingdom., Reznikov N; Department of Materials, Imperial College London, London, SW7 2AZ, United Kingdom; Department of Bioengineering, Imperial College London, London, SW7 2AZ, United Kingdom; Institute of Biomedical Engineering, Imperial College London, London, SW7 2AZ, United Kingdom., Nitiputri K; Department of Materials, Imperial College London, London, SW7 2AZ, United Kingdom; Department of Bioengineering, Imperial College London, London, SW7 2AZ, United Kingdom; Institute of Biomedical Engineering, Imperial College London, London, SW7 2AZ, United Kingdom., Nommeots-Nomm A; Department of Materials, Imperial College London, London, SW7 2AZ, United Kingdom., O'Donnell MD; Department of Materials, Imperial College London, London, SW7 2AZ, United Kingdom., Lange C; Max Planck Institute of Colloids and Interfaces, Department of Biomaterials, Research Campus Golm, Potsdam, Germany., Seidt BM; Max Planck Institute of Colloids and Interfaces, Department of Biomaterials, Research Campus Golm, Potsdam, Germany., Kim TB; Department of Materials, Imperial College London, London, SW7 2AZ, United Kingdom., Solanki AK; Department of Materials, Imperial College London, London, SW7 2AZ, United Kingdom; Department of Bioengineering, Imperial College London, London, SW7 2AZ, United Kingdom; Institute of Biomedical Engineering, Imperial College London, London, SW7 2AZ, United Kingdom., Tallia F; Department of Materials, Imperial College London, London, SW7 2AZ, United Kingdom., Young G; Department of Materials, Imperial College London, London, SW7 2AZ, United Kingdom., Lee PD; Department of Materials, Imperial College London, London, SW7 2AZ, United Kingdom; Mechanical Engineering, University College London, Torrington Place, London, WC1E 7JE, United Kingdom., Pierce BF; Department of Materials, Imperial College London, London, SW7 2AZ, United Kingdom; Department of Bioengineering, Imperial College London, London, SW7 2AZ, United Kingdom; Institute of Biomedical Engineering, Imperial College London, London, SW7 2AZ, United Kingdom., Wagermaier W; Max Planck Institute of Colloids and Interfaces, Department of Biomaterials, Research Campus Golm, Potsdam, Germany., Fratzl P; Max Planck Institute of Colloids and Interfaces, Department of Biomaterials, Research Campus Golm, Potsdam, Germany., Goodship A; Institute of Orthopaedics and Musculoskeletal Science, University College London, London, WC1E 6BT, United Kingdom., Jones JR; Department of Materials, Imperial College London, London, SW7 2AZ, United Kingdom., Blunn G; Institute of Orthopaedics and Musculoskeletal Science, University College London, London, WC1E 6BT, United Kingdom; School of Pharmacy and Biomedical Sciences, University of Portsmouth, PO1 2DT Portsmouth, United Kingdom. Electronic address: gordon.blunn@port.ac.uk., Stevens MM; Department of Materials, Imperial College London, London, SW7 2AZ, United Kingdom; Department of Bioengineering, Imperial College London, London, SW7 2AZ, United Kingdom; Institute of Biomedical Engineering, Imperial College London, London, SW7 2AZ, United Kingdom. Electronic address: m.stevens@imperial.ac.uk.

Publikováno v: Biomaterials [Biomaterials] 2019 Jul; Vol. 209, pp. 152-162. Date of Electronic Publication: 2019 Mar 25.