Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Pierangela Sabbattini"'
Autor:
Irene Roberts, Tian Li Wang, Pierangela Sabbattini, Luca Magnani, Xiaolin Xiao, Keren Keren, Kikkeri N. Naresh, Richard Szydlo, Anastasios Karadimitris, Valentina S. Caputo, Bien Bergonia, Kanagaraju Ponnusamy, Nikolaos Trasanidis, Ioannis Kostopoulos, Aristeidis Chaidos, Paudel Reema, Holger W. Auner, Yao-An Shen, Alexia Katsarou
Understanding the biological and clinical impact of copy number aberrations (CNA) in cancer remains an unmet challenge. Genetic amplification of chromosome 1q (chr1q-amp) is a major CNA conferring adverse prognosis in several cancers, including the b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::920ab9717d9ee96672e16bd5a4ccaad7
https://doi.org/10.1101/2021.11.17.469031
https://doi.org/10.1101/2021.11.17.469031
Autor:
Pierangela Sabbattini, Niall Dillon, Matteo Martufi, Moumita Sarkar, Yi-Fang Wang, Dirk Dormann, Chad Whilding, Monica Roman-Trufero
Publikováno v:
Molecular biology of the cell. 32(22)
Mesendoderm cells are key intermediate progenitors that form at the early primitive streak (PrS) and give rise to mesoderm and endoderm in the gastrulating embryo. We have identified an interaction between CNOT3 and the cell cycle kinase Aurora B tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::438a24ee2ca0fc4f9ac14df77a0c082a
https://pubmed.ncbi.nlm.nih.gov/34613789
https://pubmed.ncbi.nlm.nih.gov/34613789
Autor:
Greg Crawford, Pierangela Sabbattini, Mohammad M. Karimi, Sanjay Khadayate, Natalia Kunowska, Roshni de Souza, Anne-Marie Moody, Yi-Fang Wang, Jessica Strid, Alexis R. Barr, Inesa Thomsen, Niall Dillon
RUNX1 is a transcription factor that plays key roles in haematopoietic development and in adult haematopoiesis and lymphopoiesis. Here we report that RUNX1 is also involved in controlling the dynamics of cell cycle entry of naïve resting B cells in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50357456b500cef83f8b309c69bb9c7f
https://doi.org/10.1101/2020.12.01.406744
https://doi.org/10.1101/2020.12.01.406744
Autor:
Yi-Fang Wang, Matteo Martufi, Dirk Dormann, Chad Whilding, Pierangela Sabbattini, Niall Dillon, Moumita Sarkar, Monica Roman-Trufero
Mesendoderm cells are key intermediate progenitors that form at the early primitive streak (PrS) and give rise to mesoderm and endoderm in the gastrulating embryo. We have identified an interaction between CNOT3 and the cell cycle kinase Aurora B, wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dafe24435511427979a42616567f82e4
https://doi.org/10.1101/756932
https://doi.org/10.1101/756932
Autor:
Thomas L. Carroll, Pierangela Sabbattini, Emily Brookes, Per-Henrik Holmqvist, Niall Dillon, Simon Arthur, Alberto Frangini, Natalia Kunowska, Svetlana Nikic, Ana Pombo, Marcela Sjoberg
Publikováno v:
Molecular Biology of the Cell
Polycomb-repressed genes are marked by H3K9me3 and H3K27me3 in pluripotent ES cells, but the effects of this combination are altered by H3S10 phosphorylation in differentiated cells. Acquisition of H3K9me3/S10ph at Polycomb-target genes during differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9654e47fb0a4abae262930ffc0acbcd1
http://europepmc.org/articles/PMC3952858
http://europepmc.org/articles/PMC3952858
Autor:
Jonathan, Bond, Renae, Domaschenz, Mónica, Roman-Trufero, Pierangela, Sabbattini, Isabel, Ferreiros-Vidal, Gareth, Gerrard, Vahid, Asnafi, Elizabeth, Macintyre, Matthias, Merkenschlager, Niall, Dillon
Publikováno v:
Oncotarget
Ikaros and Foxp1 are transcription factors that play key roles in normal lymphopoiesis and lymphoid malignancies. We describe a novel physical and functional interaction between the proteins, which requires the central zinc finger domain of Ikaros. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::82a34bb28bdd71db55a47ddf590892de
https://pubmed.ncbi.nlm.nih.gov/27588474
https://pubmed.ncbi.nlm.nih.gov/27588474
Autor:
Niall Dillon, Svetlana Nikic, Marcela Sjoberg, Geoffrey Kemball-Cook, Andrew Georgiou, Claudia Canzonetta, Holger W. Auner, Pierangela Sabbattini
Publikováno v:
The EMBO Journal
Combinatorial modifications of the core histones have the potential to fine-tune the epigenetic regulation of chromatin states. The Aurora B kinase is responsible for generating the double histone H3 modification tri-methylated K9/phosphorylated S10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::130987b4fa69b5a084144c5e7bead6f6
http://europepmc.org/articles/PMC2048755
http://europepmc.org/articles/PMC2048755
Autor:
Pierangela Sabbattini, Niall Dillon
Publikováno v:
Seminars in Immunology. 17:121-127
The lambda5 and VpreB genes encode the components of the surrogate light-chain, which forms part of the pre-B cell receptor. In mouse, the lambda5 and VpreB1 genes of mouse are closely linked and coordinately regulated by a locus control region (LCR)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af76c772abb218d6b6333b9d2bbc29d3
https://doi.org/10.1016/j.smim.2005.01.004
https://doi.org/10.1016/j.smim.2005.01.004
Autor:
Niall Dillon, Andrew Georgiou, Gary Warnes, Pierangela Sabbattini, Cheok-man Chow, Mats Lundgren
Publikováno v:
The EMBO Journal. 20:2812-2822
The Ikaros family of proteins are DNA binding factors required for correct development of B and T lymphocytes. Cytogenetic studies have shown that these proteins form complexes with pericentromeric heterochromatin in B cells, and the colocalization o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee7e3528b21eed6f2e06db8f983f4b16
https://doi.org/10.1093/emboj/20.11.2812
https://doi.org/10.1093/emboj/20.11.2812
Autor:
Pierangela Sabbattini, Niall Dillon, Sophie Minaee, Andrew Georgiou, Mats Lundgren, Cheok-man Chow
Publikováno v:
Cell. 103(5):733-743
The mechanisms of transcriptional activation in heterochromatin were investigated by using FISH to directly visualize changes in chromatin organization during activation of a heterochromatic λ5 transgene. A DNase I hypersensitive site was shown to r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::382cc24bc8a7e803ce70116bde469cbb